Navigation Links
Cracking the egg

Sexual reproduction is not necessarily sexy (especially when scientists start analyzing it), but it is fascinating. As we all know, the basics entail bringing together an egg and a sperm, a whole lot of cell division and growth, and sooner or later a young organism that carries a mix of genes from both parents. There are many startling events along the way, but one of the most fundamental and important is the transition from unfertilized egg to fertilized embryo.

Think about it: The former is and will remain an egg if left alone, while the latter has within it the means to unleash the dazzling cascade of events needed to create a viable organism. What's already in the egg that enables it to make the transition? How is it the same and how is it different across species? And what changes occur when the egg is fertilized? Scientists led by Drs Barbara Knowles and Alexei Evsikov at The Jackson Laboratory have certainly been thinking about this topic for years. A new paper in the journal Genes & Development presents significant new information about what is happening within a fully grown (pre-ovulatory) egg and some of the changes that occur during transition to the two-cell stage embryo.

The researchers performed a large-scale survey of thousands of fragments of mouse egg cDNA. The cDNA fragments are reverse coded from messenger RNA and therefore indicate which genes are being expressed. They identified 5,400 active genes in the fully grown egg, about a tenth of which are unique to egg cells. Interestingly, the process of getting ready for fertilization requires more genetic activity than early embryo development. There's a far greater diversity of RNAs in the egg cell than in the two-cell embryo, perhaps because the embryo is independent and the pre-ovulatory egg must still coordinate signals with surrounding tissues.

Another discovery was that 80% of the expressed genes identified in mouse eggs are also expressed in the eggs of two other
'"/>

Source:Jackson Laboratory


Page: 1 2

Related biology news :

1. Cracking the olfactory code in bees
2. Cracking the perception code
3. Cracking the genetic code for control of gene expression
4. Cracking open the black box of autoimmune disease
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cracking the egg

(Date:5/19/2015)... May 18, 2015 Fingerprint Cards (FPC) ... FPC1025, FPC1145, FPC1155 and FPC1035 from one if its module ... and including Q3 2015 and the sensors will be used ... order values for 2015 hereby amount to 740 MSEK to ... of 140 MSEK and a number of smaller orders not ...
(Date:5/14/2015)... , May 14, 2015  Verificient Technologies, ... verification and online remote proctoring, announced a ... (SaaS) company and creator of the Canvas ... the two companies will benefit from the ... As a fully integrated multifactor ...
(Date:5/8/2015)... Synaptics Inc. (NASDAQ: SYNA ), the leading ... the executive management team will present at the following investor ... Telecom Conference Date: May 18, 2015 Time: 10:40am ... Cowen and Company Technology, Media & ... The New York Palace Hotel, New York, NY ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Synaptics to Present at Upcoming Investor Conferences 2
... MIT are developing a tiny sensor that could be ... toxic industrial chemicals and chemical warfare agents, much more ... the common techniques of gas chromatography and mass spectrometry ... size of a computer mouse. Eventually, the team, led ...
... findings that begin to characterize the poorly understood interaction ... a niche. The findings appear in todays ... demonstrated that differentiation-defective Drosophila ovarian germline stem cells (GSCs), ... stem cells for a position in the niche. They ...
... Harbor Laboratorys (CSHL) researcher Raffaella Sordella, Ph.D. was awarded ... Conquer Lung Cancer. The two-year grant will fund CSHLs ... genetic mutations that appear to be a trigger in ... deaths in the United States. The mutations, called ...
Cached Biology News:MIT gas sensor is tiny, quick 2Cold Spring Harbor Laboratory's lung cancer research program awarded $100,000 grant 2
(Date:5/26/2015)... MA (PRWEB) May 26, 2015 Just ... addresses a long-standing unmet biomedical need does not guarantee ... a problem that has seen many prior failures is ... gaining acceptance and use is an irony that is ... a small, new start-up company, Asymmetrex has ...
(Date:5/25/2015)... Phenome Networks, a software-as-a-service plant breeding ... beginning May 31st, of its next-generation Phenome One software. ... Phenome Networks’ lead in the plant breeding market, through ... breeding workflow based on years of experience with plant ... and more. The new version of Phenome One, Phenome ...
(Date:5/22/2015)... NJ (PRWEB) May 22, 2015 ... new white paper that explores the potential of big ... The white paper was developed to help life sciences ... can leverage data to gain critical business insights. , ... large amounts of data driven by patient profiling, compliance ...
(Date:5/21/2015)... May 21, 2015 Specialty Pharmacy ... and been admitted to BPA Worldwide as a ... will track audience data for Specialty Pharmacy Times ... , “By becoming a member of BPA Worldwide, ... providing our clients with the most reliable, unequaled ...
Breaking Biology Technology:In August Asymmetrex Will Present Details of Its Crowdsourcing Campaign to Determine the Extent of Application of New Technologies for Counting Adult Tissue Stem Cells 2In August Asymmetrex Will Present Details of Its Crowdsourcing Campaign to Determine the Extent of Application of New Technologies for Counting Adult Tissue Stem Cells 3Phenome Networks Announces its Next Generation Plant Breeding Management and Analytics Software 2Phenome Networks Announces its Next Generation Plant Breeding Management and Analytics Software 3New White Paper Explores the Potential of Big Data Analytics in Life Sciences and Healthcare 2Specialty Pharmacy Times Joins BPA Worldwide 2
... March 29, 2011 AMDeC, LLC ... Program to include products offered by Sigma® Life ... of Sigma-Aldrich® (Nasdaq: SIAL).  AMDeC is a consortium ... New York region that is focused on increasing ...
... 2011 Tibotec Pharmaceuticals announced today that four abstracts ... C protease inhibitor, have been accepted for presentation at ... the Study of the Liver (EASL) in Berlin, Germany, ... The four abstracts for TMC435 support Tibotec,s continued efforts ...
... 29, 2011 Soligenix, Inc. (OTC Bulletin Board: ... biopharmaceutical company, announced today its financial results for the ... revenues for the year ended December 31, 2010 were ... representing a decrease of $868,409, or 31%.  During 2009, ...
Cached Biology Technology:Sigma® Life Science Joins AMDeC's Vendor Partnership Program, Further Enhancing Value to Academic Medical Research Centers 2Sigma® Life Science Joins AMDeC's Vendor Partnership Program, Further Enhancing Value to Academic Medical Research Centers 3Sigma® Life Science Joins AMDeC's Vendor Partnership Program, Further Enhancing Value to Academic Medical Research Centers 4Tibotec Advances Global Clinical Research Program for TMC435 in HCV; Will Present Four Abstracts Evaluating Safety and Efficacy at EASL 2Tibotec Advances Global Clinical Research Program for TMC435 in HCV; Will Present Four Abstracts Evaluating Safety and Efficacy at EASL 3Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 2Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 3Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 4Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 5
... for microRNA expression profiling ,miRCURY ... Locked Nucleic Acid (LNA) technology to provide ... short microRNA (miRNA) targets. miRCURY LNA Arrays ... RNA (no need for microRNA enrichment) labeled ...
... slightly cloudy liquid. Yellow, oily, bacterial ... each containing 10 ml of Freund's ... proportions by weight: 85% Drakeol 5NF, ... and 0.1% Mycobacterium butyricum ...
With sodium bicarbonate. Sterile, Cell culture tested...
For removal of the zona pellucida. Sterile, Mouse Embryo tested...
Biology Products: