Navigation Links
Cornell researcher helping develop quick, cheap HIV/AIDS test

A Cornell researcher is working to develop a quick, simple and cheap immune-system test for people in the developing world. It could help HIV/AIDS sufferers in the poorest countries get appropriate treatment to extend their lives, possibly by as much as 10 to 15 years.

The work is part of an $8.6 million international consortium, called the CD4 Initiative, led by Imperial College in London and funded by the Bill and Melinda Gates Foundation. Antje J. Baeumner, Cornell associate professor of biological and environmental engineering, has been awarded an initial $386,000 (subject to annual renewal for four years) from the consortium to determine a way to simply assess the critical HIV/AIDS immune system factors -- CD4 T-cell count, or CD4+ T-lymphocytes count -- in the blood.

"When patients are infected with HIV/AIDS, the number of circulating CD4 T-cells drops significantly," explains Baeumner. "If they get the appropriate retroviral treatment, their life span can be increased by many years. CD4 counts assist in the decisions on when to initiate and when to stop the treatment, which makes this test so important.

"While such testing is routine in Western countries -- and used repeatedly over the course of treatment to see if interventions are effective -- it's unavailable to many people in the developing world, especially in rural areas."

For the first two years, Baeumner will work on developing a test for CD4+ T-lymphocytes in the blood that can be likened to a pregnancy test using biosensor nanovesicles (microscopic, fluid-filled pouches made of phospholipids that can deliver drugs -- also known as liposomes) to enhance the signal. Several other consortium organizations also are working on the similar product development so that the best possible test can be developed in the shortest time possible.

"Currently, most people in the world, such as those in Third World countries, infected with HIV have no access to detection tech nology," explains Baeumner, noting that 40 million people live with HIV/AIDS worldwide, many of them in areas where electricity is unreliable or nonexistent, water quality is poor and there are few, if any, highly skilled health-care technicians. "This test, however, is being developed to endure harsh temperature conditions and be truly simple -- no batteries will be needed, for example."


Source:Cornell University News Service

Related biology news :

1. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
2. Cornell finds natural selection in humans
3. Cornell researchers find serious fish virus in Northeast for first time
4. Cornell lab confirms deadly fish virus spreading to new species
5. U of M researcher examines newly emerging deadly disease
6. NYU researchers simulate molecular biological clock
7. Vital step in cellular migration described by UCSD medical researchers
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. UCSD researchers maintain stem cells without contaminated animal feeder layers
10. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
11. New protein discovered by Hebrew University researchers
Post Your Comments:

(Date:5/9/2016)... , UAE, May 9, 2016 ... when it comes to expanding freedom for high net ... Even in today,s globally connected world, there is ... conferencing system could ever duplicate sealing your deal with ... obtaining second passports by taking advantage of citizenship via ...
(Date:4/26/2016)... and LONDON , April 26, ... of EdgeVerve Systems, a product subsidiary of Infosys ... announced a partnership to integrate the Onegini mobile ...      (Logo: ) ... customers enhanced security to access and transact across ...
(Date:4/15/2016)... Research and Markets has announced ... 2016-2020,"  report to their offering.  , ... global gait biometrics market is expected to grow ... 2016-2020. Gait analysis generates multiple variables ... to compute factors that are not or cannot ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... Amgen, will join the faculty of the University of North Carolina Kenan-Flagler ... of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s ...
(Date:6/24/2016)... ... , ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension ... are higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... bottom of the cuvette holder. , FireflySci has developed several Agilent flow cell ...
(Date:6/23/2016)... - FACIT has announced the creation of a ... Propellon Therapeutics Inc. ("Propellon" or "the Company"), to ... of first-in-class WDR5 inhibitors for the treatment of ... an exciting class of therapies, possessing the potential ... patients. Substantial advances have been achieved with the ...
(Date:6/23/2016)... 23, 2016  The Biodesign Challenge (BDC), a university ... to harness living systems and biotechnology, announced its winning ... New York City . ... showcased projects at MoMA,s Celeste Bartos Theater during the ... MoMA,s senior curator of architecture and design, and ...
Breaking Biology Technology: