Navigation Links
Cord blood cells may widen treatment window for stroke

An experimental treatment that spares disability from acute stroke may be delivered much later than the current three-hour treatment standard ?a potential advance needed to benefit more stroke victims.

Researchers at the University of South Florida found that human umbilical cord blood cells administered to rats two days following a stroke greatly curbed the brain's inflammatory response, reducing the size of the stroke and resulting in greatly improved recovery. The rats' inflammatory response to injury from stroke peaked 48 hours after the brain attack, which was when intravenous delivery of the cells appeared most beneficial.

"We were very surprised," said principal investigator Alison Willing, PhD, a neuroscientist at the USF Center of Excellence for Aging and Brain Repair. "In some animals, the stroke initially damaged half the brain, but after treatment with the cord blood cells they were functioning normally.

"These findings show we are able to rescue neurons at a time when most research suggests they are already dead."

Dr. Willing presented the preliminary findings Nov. 12 at the Society for Neuroscience annual meeting in Washington, DC.

The only drug currently approved for ischemic stroke treatment is tPA (tissue plasminogen activator), which breaks up blood clots ?the cause of most strokes. However, tPA must be given within three hours following a stroke to be effective and few patients arrive at the hospital quickly enough to receive it. Even when a patient meets the recommended three-hour treatment criteria, smaller hospitals often lack ready access to a CT scan, a test needed to rule out a hemorrhagic stroke caused by a burst blood vessel. The drug can worsen this less common type of stroke.

"New and more flexible treatments are needed to help more patients," Dr. Willing said. "Cord blood treatment in rats is successful in alleviating, even eliminating, the disabling effects of both ischemic and hemorrhagic
'"/>

Source:University of South Florida Health


Page: 1 2

Related biology news :

1. White blood cell waste disposal system plays critical regulatory role
2. Epstein-Barr virus protein crucial to its role in blood cancers
3. New insight into regulation of blood stem cells
4. Nano-bumps could help repair clogged blood vessels
5. First technology to remove prions that cause vCJD from blood launched
6. Breakthrough isolating embryo-quality stem cells from blood
7. Thai spice helps cut blood sugar swings
8. Study shows humans have ability to track odors, much like bloodhounds
9. Mad cow proteins successfully detected in blood
10. Unexpected lock and key mechanism found for the assembly of tumor blood vessels
11. Redesigned protein accelerates blood clotting
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cord blood cells may widen treatment window for stroke

(Date:7/10/2014)... 1, 2014 Smart technology emphasis grows ... and improved security: NXT-ID, Inc. (OTCBB: NXTD), eBay Inc. (NASDAQ: ... ), Apple Inc. (NASDAQ: AAPL ), Visa Inc. ... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused ... the second series of 30 second spots on CNBC for ...
(Date:7/10/2014)... SHELTON, Conn. , July 2, 2014 NXT-ID, Inc., ... market, reports that CEO Mr. Gino Pereira was ... radio show in Tampa Florida . Mr. ... radio host Cedric Harris and how the Wocket™ ... secure alternative.  Cedric Harris tells ...
(Date:7/10/2014)... GOTHENBURG, Sweden , July 7, 2014 ... won its first major design win (DW). A Chinese Top ... with the planned start of mass production in October 2014. ... with a Chinese Top 5 smartphone OEM, which has a ... 2014 and a target sales volume for this phone of ...
Breaking Biology News(10 mins):Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 4FPC Wins DW for 1021 Touch Sensor for Flagship Smartphone from Chinese Top 5 Smartphone OEM 2
... Va.Coinciding with the observance of Nuclear Medicine Week (October ... (October), SNM released today a new fact sheet highlighting ... improving the ways in which breast cancer is diagnosed ... effective, safe and painless imaging tool for diagnosing and ...
... a study in mice has found that inactivating a ... increase energy expenditure and help lower diet-induced obesity. These ... might lead to some new roads in weight-loss ... to continually "burn fat" in order to maintain body ...
... of spring: a swarm of bees on the move. But how ... of the community know the way remains a mystery. Curious to ... homes, Tom Seeley, a neurobiologist from Cornell University, and engineers Kevin ... to find out how swarms are guided to their new home ...
Cached Biology News:SNM releases new fact sheet on breast cancer and molecular imaging 2Making metabolism more inefficient can reduce obesity 2Bee swarms follow high-speed 'streaker' bees to find a new nest 2
(Date:7/11/2014)... -- Research and Markets  has announced the addition ... Industry Analysis, Size, Share, Growth, Trends and Forecast to ... http://photos.prnewswire.com/prnh/20130307/600769 Transfection is a ... RNA) into cells. This technology helps the cells to ... metabolism by affecting the nuclear genes. The transfection technology ...
(Date:7/11/2014)... , July 11, 2014 EPFL ... announce the appointment of John P. Donoghue . ...   in  Geneva . The new ... Biotech in Geneva , has named ... neuroscientists. John P. Donoghue , founder of Brown ...
(Date:7/11/2014)... , July 11, 2014  Researchers have ... three-dimensional images. The new technology, called Virtual Finger, ... small structures like neurons and synapses using the ... unique technology makes 3D imaging studies orders of ... at an unprecedented level across many areas of ...
(Date:7/10/2014)... Burkina Faso (PRWEB) July 10, 2014 ... Faso, today have access to an additional family ... increase access to contraception at all levels of ... a lower-dose formulation of a widely used contraceptive—Pfizer’s ... system. , Burkina Faso is the first of ...
Breaking Biology Technology:International Transfection Technology Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2019 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6
... JOLLA, Calif., Sept. 11 TorreyPines Therapeutics,Inc. (Nasdaq: ... Kurtz, President and,Chief Executive Officer of TorreyPines, will ... Tuesday, September 18th at 2:30 p.m., local,time (5:30 ... presentation will be available live. You can,access the ...
... of Novel Strategies to Induce and Monitor Humoral and ... Infection by Respiratory Viruses, LEIDEN, The Netherlands, September ... Institute Pharma is being conducted by a,multi-member Dutch consortium ... development. The aim of the project is to develop,novel ...
... Sept. 11 Jazz,Pharmaceuticals, Inc. (Nasdaq: JAZZ ... Chief Executive Officer, will provide a corporate,presentation at ... NY on,September 24, 2007 at 4:00 p.m. Eastern ... may be accessed by visiting the,Investors section of ...
Cached Biology Technology:A Large-Scale Research Project by a Dutch Consortium Addressing a Global Problem 2A Large-Scale Research Project by a Dutch Consortium Addressing a Global Problem 3A Large-Scale Research Project by a Dutch Consortium Addressing a Global Problem 4A Large-Scale Research Project by a Dutch Consortium Addressing a Global Problem 5
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
... This product is expected to ... mammalian species but has not been ... single precipitin line against partially purified ... to react with all forms of ...
Recorder, 6", 7 Day, 1 Pen, 0 to 100°C, 220V, 50/60 Hz, for 4520, Customer Installed...
... Pro upgrade for Shimadzu Phoretix 2D, Expression ... statistical tools for comparative gel analysis studies ... Data base add on component ... version 9i release 2 client software). ...
Biology Products: