Navigation Links
Computer simulation hints at new HIV drug target

uter program to block the flaps from opening by expanding the gap between "ear" and "cheek." A new type of drug that binds there and controls flap motion could enhance the ability of the current protease inhibitors to bind to the active site, or it could offer a new way of inhibiting protease activity from afar by itself, Perryman suggested.

Now that he can prevent the simulated flaps from opening by using an artificial force, Perryman and co-author Jung-Hsin Lin of National Taiwan University hope to discover and develop real compounds that can regulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein engineering with Mayo, so that he can apply it to the design of therapeutic proteins as well as biomolecular electronics devices.


'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3 4 5

Related biology news :

1. Computers to be used to find blueprint for new influenza drug
2. Large-scale Computer Simulations Reveal New Insights Into Antibiotic Resistance
3. Computers close in on protein structure prediction
4. Computer modeling reveals hidden conversations within cells
5. Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever
6. Computer-chemistry yields new insight into a puzzle of cell division
7. Computers to save unique type of American red squirrel
8. Computer scientist sorts out confusable drug names
9. Computer-based games enhance mental function in patients with Alzheimers
10. Computer scientists unravel language of surgery
11. Computer with brain connections changing quality of life of paralyzed
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Computer simulation hints new HIV drug target

(Date:1/22/2015)... Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), ... crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz ... production capacity to meet customer demand. ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by ...
(Date:1/22/2015)...  A man-made form of insulin delivered by nasal spray ... adults with mild cognitive impairment and Alzheimer,s disease dementia, ... Wake Forest Baptist Medical Center. The study,s ... impairment (MCI) or mild to moderate Alzheimer,s dementia (AD). ...
(Date:1/22/2015)... NEW YORK , Jan. 21, 2015  Analyst Report Issued ... Credit Card Brands report showed that planet-wide, transactions at merchants ... 2011, while the total number of credit, debit, and prepaid ... the U.S. were victims of fraudulent card usage in 2012, ...
Breaking Biology News(10 mins):FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... disabilities who are struggling to regain the use of ... engineers and students from Rochester Institute of Technology. ... the human body, to improve the performance of external ... disabilities, such as strokes or major spinal cord injuries, ...
... know all there is to know about Escherichia coli, ... has more than four thousand genes, and the functions ... Siegele, a biology professor at Texas A&M University whose ... , Harmless E. coli strains are normally found in ...
... Understanding, through its Institute for Arctic Studies, has ... Science Foundation through its Integrative Graduate Education and ... grant supports the development of an interdisciplinary doctoral ... a focus on rapid environmental change. "This grant ...
Cached Biology News:Robotics research: Enhancing the lives of people with disabilities 2GIANT-Coli: A novel method to quicken discovery of gene function 2Dartmouth awarded NSF grant for new polar sciences, engineering grad program 2Dartmouth awarded NSF grant for new polar sciences, engineering grad program 3
(Date:1/22/2015)... (PRWEB) January 22, 2015 Selexis SA, ... mammalian Research Cell Banks (RCBs) used for drug discovery ... Cell Banks will include Next-Generation Sequencing (NGS) ... architecture de-risks biologic manufacturing by ensuring the integrity of ...
(Date:1/22/2015)... CAMBRIDGE, Mass. , Jan. 22, 2015   GenoSpace , ... suite of tools to enable the broad use of genomic, ... today announced the appointment of Michelle Munson , CEO ... independent director. Logo - http://photos.prnewswire.com/prnh/20150122/170713 ...
(Date:12/24/2014)... 24, 2014  Vermillion, Inc. (Nasdaq:   VRML), a ... today that the Company closed its previously announced ... Jack W. Schuler , Birchview Fund LLC ... million, before offering expenses.  The proceeds will be ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 ... designed to introduce cutting edge communication technology, provide ... platform upgrades. This webinar series demonstrates online communication ... to leverage web conferencing’s most innovative and powerful ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
... MATK ) announced today that life,sDHA(TM), its ... and heart health, is now available to,consumers in ... Challenge,Dairy Products, Inc. Challenge 15 oz. Spreadable Butter ... Founded in 1911, Challenge Dairy Products, Inc., is ...
... Calif., Feb. 4 CV,Therapeutics, Inc. (Nasdaq: ... the companies have entered into an agreement under,which ... technology to develop a drug eluting stent (DES). ... development milestone payments,royalties and other potential payments on ...
... Outside of North ... America, ... facility in Cartago, Costa Rica has been,recognized with the 2008 Shingo Prize ... Prize outside North America,-- is being honored for its achievements in driving ...
Cached Biology Technology:Challenge Spreadable Butter Now Features Martek's life'sDHA(TM) 2Challenge Spreadable Butter Now Features Martek's life'sDHA(TM) 3CV Therapeutics and Medlogics Device Corporation Sign Licensing Agreement for CVT's Innovative Stent Coating Technology 2CV Therapeutics and Medlogics Device Corporation Sign Licensing Agreement for CVT's Innovative Stent Coating Technology 3Baxter's Costa Rica Facility Recognized With Shingo Prize for Excellence in Manufacturing 2
... Zyagen tissue microarrays are derived from Paraffin ... rigorous quality control procedures to ensure the ... manually assembled in one block, sectioned at ... on coated slides. Sections are large (3-5 ...
... derived from frozen embedded tissue blocks, which ... to ensure the highest quality. Tissues of ... block, sectioned at a thickness of 7microns ... large (3-5mm in diameter) in comparison to ...
... Optimal Microdissection , CapSure HS and CapSure ... rapid extraction of populations of pure cells ... Laser Capture Microdissection., Ensure the Integrity ... , All CapSure LCM Caps have a ...
... , CapSure HS and CapSure Macro LCM ... of populations of pure cells from tissue ... Microdissection., Ensure the Integrity of Microdissected ... CapSure LCM Caps have a patented transfer ...
Biology Products: