Navigation Links
Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever

body-dependent enhancement creates oscillations, or "booms and busts" in the incidence of dengue virus infections. Enhancement results in larger booms, but also deeper troughs in incidence, which lead to extinction. Although the computer models were specifically developed for dengue, the researchers believe the results could apply to any disease in which partial immunity increases pathogen replication rates.

"Experimental dengue vaccines will soon be entering into large-scale clinical trials. We must understand the processes that affect transmission--such as antibody-dependent enhancement--to design optimal dengue vaccination strategies," said Donald S. Burke, MD, senior author of the study and professor in the Department of International Health at the Bloomberg School.

"Dynamic effects of antibody-dependent enhancement on the fitness of viruses" was written by Derek A. T. Cummings, Ira B. Schwartz, Lora Billings, Leah B. Shaw and Donald S. Burke. Cummings and Burke are with the Johns Hopkins Bloomberg School of Public Health. Schwartz and Shaw are with the Naval Research Laboratory, Washington, D.C., and Billings is with Montclair State University.


'"/>

Source:Johns Hopkins University Bloomberg School of Public Health


Page: 1 2

Related biology news :

1. Computers to be used to find blueprint for new influenza drug
2. Large-scale Computer Simulations Reveal New Insights Into Antibiotic Resistance
3. Computers close in on protein structure prediction
4. Computer modeling reveals hidden conversations within cells
5. Computer-chemistry yields new insight into a puzzle of cell division
6. Computers to save unique type of American red squirrel
7. Computer simulation hints at new HIV drug target
8. Computer scientist sorts out confusable drug names
9. Computer-based games enhance mental function in patients with Alzheimers
10. Computer scientists unravel language of surgery
11. Computer with brain connections changing quality of life of paralyzed
Post Your Comments:
(Date:7/30/2015)... VIEW, Calif. , July 30, 2015 /PRNewswire/ ... and services for gene function analysis and biomarker ... Guide RNA (sgRNA) Knockout Library targeting all human ... specifically and permanently "knock out" a gene,s function. ... provides a high throughput screening tool so that ...
(Date:7/21/2015)... , July 21, 2015 Today, ZTE ... Already received as well as expected revenues in 2015 that relate ... FPC,s communicated revenue guidance of approximately 2,200 MSEK for 2015. ... is a leading smartphone manufacturer in China ... FPC1 02 5 for Axon , ...
(Date:7/13/2015)... , Jul. 13, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/188684 for BEHAVIORAL-DIRECTED AUTHENTIATION ... new convenient and secure method to make payments.  ... payment methods, introduced with its groundbreaking voice-direct payment ...
Breaking Biology News(10 mins):CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2FPC's Touch Fingerprint Sensor FPC1025 in ZTE's Smartphone Axon 2NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4
... a climate as prone to extremes as Canada,s, buildings ... innovative solutions are being explored through the NSERC Smart ... initiative headquartered at Concordia, which has just received $1 ... "Through the ecoENERGY Innovation Initiative, our Government ...
... MNMay 2, 2013UnitedHealth Group and the Minneapolis Heart Institute ... of New Ulm, Minn., recently announced two grants from ... will fund weight management and nutrition initiatives for Hearts ... a research and demonstration project with a goal of ...
... to announce the launch of Environmental Science & ... accelerate the pace of research across the environmental field ... leading publishing outlet to highlight urgent critical findings in ... release its first issue January 2014 and open for ...
Cached Biology News:$1 million for smart energy solutions 2UnitedHealth Group grants more than $1 million for the heart of New Ulm project 2New ACS journal Environmental Science and Technology Letters to rapidly publish urgent research 2New ACS journal Environmental Science and Technology Letters to rapidly publish urgent research 3
(Date:8/3/2015)... 2015 E-QURE Corp. (OTCQB: EQUR), ... Bio-electrical Signal Therapy device ("BST Device"), a new and ... heal chronic wounds, today announced that the Company has ... distributor specializing in medical devices, for the marketing and ... a 70 years old, sales, marketing and distribution company ...
(Date:8/3/2015)... NEW YORK , August 3, 2015 ... "Global Market Study on 3D Cell Culture: ... published by Persistence Market Research, the global 3D cell culture ... is expected to expand at a CAGR of 29.1% ... View Full Report with TOC:  http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp ...
(Date:8/3/2015)... ... 2015 , ... Sterlitech Corporation introduces the compact, quiet, and ... laboratory equipment. With optimized features, such as PTFE-coated contact surfaces, an oil-free design, ... solution for a broad range of vacuum filtration applications. , Featuring a 1/7 ...
(Date:7/31/2015)... ... July 31, 2015 , ... Global ... and premium industry insights on the global resorcinol industry. The report highlights the ... of vivid market scenarios and analysis of primary and secondary inputs from the ...
Breaking Biology Technology:E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4Sterlitech Launches New Line of Vacuum Pumps 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4
... Area Economic Development Corporation 's annual business-plan contest is starting ... the best business ideas from Eau Claire County. , ,For ... on March 29. Then entrants in the Creating Your ... prepare their applications. , ,Businesses judged to have the best ...
... Metavante Corporation has completed its acquisition of ... says it is expanding its Healthcare Payments Solutions ... Reynolds, who previously served as senior vice president ... Wells Fargo Institutional Trust Service, will become president ...
... , a local software and consulting firm, has teamed ... a new geographic information systems application, the companies said ... to create and distribute land records data through a ... challenges faced by organizations trying to maintain and distribute ...
Cached Biology Technology:
... ULS cDNA Synthesis and Labeling Kit generates ... experiments. First unmodified cDNA is made via ... using an Oligo(dT) primer. Unlike other methods, ... in the reverse transcription reaction. This unmodified ...
... enables fully automated hybridization of microarrays on ... been designed to offer researchers improved reproducibility, ... perform a wide range of applications. ... 485C; denaturations of up to 99C. The ...
... The user-friendly Eppendorf Thermomixer R offers ... that require shaking, heating, and cooling. ... expanded its application and temperature control ... each accommodate 24 micro test tubes, ...
... a high quality microarray scanner based on patented ... and spatial resolution. The DNAscope LM is ... microarray scanner that is upgradeable to a total ... Includes control module (computer), monitor, ...
Biology Products: