Navigation Links
Completed genome set to transform the cow

The ability of scientists to improve health and disease management of cattle and enhance the nutritional value of beef and dairy products has received a major boost with the release this week of the most complete sequence of the cow genome ever assembled.

Developed by an international consortium of research organisations, including CSIRO and AgResearch New Zealand, the new bovine sequence contains 2.9 billion DNA base pairs and incorporates one-third more data than earlier versions.

Differences in just one of these base pairs (known as single nucleotide polymorphisms or SNPs) can affect the functioning of a gene and mean the difference between a highly productive and a poorly performing animal. Over two million of these SNPs, which are genetic signposts or markers, were identified as part of the project.

Australia's representative on the US $53 million Bovine Genome Sequencing Project, CSIRO's Dr Ross Tellam, says the new map marks the end of the sequencing phase of the project, with the focus now on analysing the available data.

"This is very valuable information," Dr Tellam says. "We could potentially achieve as much improvement in cattle breeding and production in 50 years as we have over the last 8000 years of traditional farming."

Cattle geneticists will use the bovine genome as a template to highlight genetic variation within and between cattle breeds, and between cattle and other mammal species.

The head of bioinformatics research at CSIRO Livestock Industries, Dr Brian Dalrymple, says the new data is very valuable because it provides researchers with a more complete picture of the genes in a cow and how variations in the DNA code influence desirable production traits.

"We can use this data to identify those genes that are involved in important functions like lactation, reproduction, muscling, growth rate and disease resistance," Dr Dalrymple says.

The Hereford breed was selected for the bulk of the sequencing project, which began in December 2003. Holstein, Angus, Jersey, Limousin, Norwegian Red and Brahman animals were also sequenced to detect specific genetic differences between breeds.

"This is just the beginning of a revolution in the way we produce our animals and food," Dr Dalrymple says. "Once we have a complete set of genes that influence tenderness, for example, we will be able to predict that animals of a certain type, fed a particular type of pasture or grain, will consistently produce meat of a particular standard of tenderness and marbling."

He says, despite the centuries of inbreeding involved in developing different cattle breeds, most maintain a "surprisingly large" degree of genetic diversity. Contributors to the US$53 million international effort to sequence the genome of the cow (Bos taurus) include: the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH); the U.S. Department of Agriculture's Agricultural Research Service and Cooperative State Research, Education, and Extension Service; the state of Texas; Genome Canada via Genome British Columbia, The Commonwealth Scientific and Industrial Research Organization of Australia; Agritech Investments Ltd., Dairy InSight, Inc, AgResearch Ltd; the Kleberg Foundation; and the National, Texas and South Dakota Beef Check-off Funds.


Source:CSIRO Australia

Related biology news :

1. Genome Sequence for Haemophilus Influenzae Completed
2. Man and mouse share genome structures
3. Whole genome fine map of rice completed
4. Study finds more than one-third of human genome regulated by RNA
5. A bacterial genome reveals new targets to combat infectious disease
6. Scientists decipher genome of fungus that can cause life-threatening infections
7. Highly adaptable genome in gut bacterium key to intestinal health
8. Fleshing out the genome
9. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
10. wFleaBase: the Daphnia genome database
11. NHGRI targets 12 more organisms for genome sequencing
Post Your Comments:

(Date:10/29/2015)... BOSTON , Oct. 29, 2015  Connected health ... phenomena driving the explosion of technology-enabled health and wellness, ... his new book, The Internet of Healthy ... apps, sensors or smartphones even existed, Dr. Kvedar, vice ... model of health care delivery, moving care from the ...
(Date:10/27/2015)... , October 27, 2015 ... Semantic Gaze Mapping technology (ASGM) automatically maps data from ... Tracking Glasses , so that they can be ... --> Munich, Germany , October 28-29, ... maps data from mobile eye tracking videos created with ...
(Date:10/26/2015)... 2015  Delta ID Inc., a company focused on ... PC devices, announced its ActiveIRIS® technology powers the iris ... launched by NTT DOCOMO, INC in Japan ... smartphone to include iris recognition technology, after a very ... in May 2015, world,s first smartphone to have this ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... ... , ... The Academy of Model Aeronautics (AMA), led by its Executive Council, ... Grand Prix, to represent the First–Person View (FPV) racing community. , FPV racing has ... type of racing and several new model aviation pilots have joined the community because ...
(Date:11/24/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS) ... remaining 11,000 post-share consolidation (or 1,100,000 pre-share consolidation) ... B Warrants") subject to the previously disclosed November ... 2015, which will result in the issuance of ... the issuance of such shares, there will be ...
(Date:11/24/2015)... ... 2015 , ... Creation Technologies would like to extend our ... Technology Fast 500 list of the fastest growing companies in North America. , ... device that speeds up orthodontic tooth movement by as much as 50 percent. ...
(Date:11/24/2015)... -- PDL BioPharma, Inc. (PDL) (NASDAQ: PDLI ) today announced ... chief executive officer, will present at the 27 th ... New York City . The presentation will be webcast ... 9:30 a.m. EST. and go to ... 15 minutes prior to the presentation to allow for any ...
Breaking Biology Technology: