Navigation Links
Completed genome set to transform the cow

The ability of scientists to improve health and disease management of cattle and enhance the nutritional value of beef and dairy products has received a major boost with the release this week of the most complete sequence of the cow genome ever assembled.

Developed by an international consortium of research organisations, including CSIRO and AgResearch New Zealand, the new bovine sequence contains 2.9 billion DNA base pairs and incorporates one-third more data than earlier versions.

Differences in just one of these base pairs (known as single nucleotide polymorphisms or SNPs) can affect the functioning of a gene and mean the difference between a highly productive and a poorly performing animal. Over two million of these SNPs, which are genetic signposts or markers, were identified as part of the project.

Australia's representative on the US $53 million Bovine Genome Sequencing Project, CSIRO's Dr Ross Tellam, says the new map marks the end of the sequencing phase of the project, with the focus now on analysing the available data.

"This is very valuable information," Dr Tellam says. "We could potentially achieve as much improvement in cattle breeding and production in 50 years as we have over the last 8000 years of traditional farming."

Cattle geneticists will use the bovine genome as a template to highlight genetic variation within and between cattle breeds, and between cattle and other mammal species.

The head of bioinformatics research at CSIRO Livestock Industries, Dr Brian Dalrymple, says the new data is very valuable because it provides researchers with a more complete picture of the genes in a cow and how variations in the DNA code influence desirable production traits.

"We can use this data to identify those genes that are involved in important functions like lactation, reproduction, muscling, growth rate and disease resistance," Dr Dalrymple says.

The Hereford breed was selected for the bulk of the sequencing project, which began in December 2003. Holstein, Angus, Jersey, Limousin, Norwegian Red and Brahman animals were also sequenced to detect specific genetic differences between breeds.

"This is just the beginning of a revolution in the way we produce our animals and food," Dr Dalrymple says. "Once we have a complete set of genes that influence tenderness, for example, we will be able to predict that animals of a certain type, fed a particular type of pasture or grain, will consistently produce meat of a particular standard of tenderness and marbling."

He says, despite the centuries of inbreeding involved in developing different cattle breeds, most maintain a "surprisingly large" degree of genetic diversity. Contributors to the US$53 million international effort to sequence the genome of the cow (Bos taurus) include: the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH); the U.S. Department of Agriculture's Agricultural Research Service and Cooperative State Research, Education, and Extension Service; the state of Texas; Genome Canada via Genome British Columbia, The Commonwealth Scientific and Industrial Research Organization of Australia; Agritech Investments Ltd., Dairy InSight, Inc, AgResearch Ltd; the Kleberg Foundation; and the National, Texas and South Dakota Beef Check-off Funds.


'"/>

Source:CSIRO Australia


Related biology news :

1. Genome Sequence for Haemophilus Influenzae Completed
2. Man and mouse share genome structures
3. Whole genome fine map of rice completed
4. Study finds more than one-third of human genome regulated by RNA
5. A bacterial genome reveals new targets to combat infectious disease
6. Scientists decipher genome of fungus that can cause life-threatening infections
7. Highly adaptable genome in gut bacterium key to intestinal health
8. Fleshing out the genome
9. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
10. wFleaBase: the Daphnia genome database
11. NHGRI targets 12 more organisms for genome sequencing
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/20/2016)... 20, 2016  VoiceIt is excited to announce ... By working together, VoiceIt and VoicePass ... and VoicePass take slightly different approaches to voice ... security and usability. ... new partnership. "This marketing and technology ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... of Infosys (NYSE: INFY ), and Samsung SDS, ... partnership that will provide end customers with a more ... payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) ... financial services, but it also plays a fundamental part in ...
(Date:4/15/2016)... CHICAGO , April 15, 2016  A ... companies make more accurate underwriting decisions in a ... offering timely, competitively priced and high-value life insurance ... health screenings. With Force Diagnostics, rapid ... and lifestyle data readings (blood pressure, weight, pulse, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... ... STACS DNA Inc., the sample tracking software company, today announced that Dr. Hays ... DNA as a Field Application Specialist. , “I am thrilled that Dr. Young ... DNA. “In further expanding our capacity as a scientific integrator, Hays brings a wealth ...
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... at the Pennsylvania Convention Center and will showcase its product’s latest features from ... also be presenting a scientific poster on Disrupting Clinical Trials in The Cloud ...
(Date:6/23/2016)... June 22, 2016  Amgen (NASDAQ: AMGN ... QB3@953 life sciences incubator to accelerate the ... shared laboratory space at QB3@953 was created to help ... obstacle for many early stage organizations - access to ... sponsorship, Amgen launched two "Amgen Golden Ticket" awards, providing ...
Breaking Biology Technology: