Navigation Links
Comparing chimp, human DNA

Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. Instead, they may contain DNA sequences that control how gene-coding regions are activated and read.

"The differences between chimps and humans are not in our proteins, but in how we use them," said Katherine Pollard, assistant professor at the UC Davis Genome Center and the Department of Statistics.

Pollard and colleagues at UC Santa Cruz led by David Haussler looked for stretches of DNA that were highly conserved between chimpanzees, mice and rats. Then they compared those sequences to the human genome sequence, to find pieces of DNA that had undergone the most rapid change since the ancestors of chimps and humans diverged about five million years ago.

They found 202 "highly accelerated regions" or HARs, which showed a high rate of evolution between humans and chimps. Only three of those regions contain genes that are likely to encode proteins. The most dramatically accelerated region, HAR1, appears to make a piece of RNA that may have a function in brain development.

DNA, deoxyribonucleic acid, carries the genetic instructions for making a chimp, a human, a tulip or an amoeba. RNA (ribonucleic acid) is an intermediate molecule that transcribes those instructions to make proteins.

The other highly accelerated regions do not appear to code for genes at all, but many are located close to genes involved in controlling when other genes get made, or in growth and development.

"They're not in genes, but they're near genes that do some very important stuff," Pollard said.

Typically, noncoding regions of DNA evolve more rapidly than regions carrying genes, as there is no selective pressure to stop mutations from accumulating. But the human-accelerated regions are highly conserved across the other groups of animals the researchers looked at, suggesting that they do have important
'"/>

Source:University of California - Davis


Page: 1 2

Related biology news :

1. Novel technology detects human DNA mutations
2. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
3. UWs Rosetta software to unlock secrets of many human proteins
4. Genome-wide mouse study yields link to human leukemia
5. Found: Missing sequence of the human Y chromosome
6. Study finds more than one-third of human genome regulated by RNA
7. Molecular machine may lead to new drugs to combat human diseases
8. Sea skate experiment sheds light on human cell transport
9. Mouse brain tumors mimic those in human genetic disorder
10. Zebrafish may hold key to understanding human nerve cell development
11. Yale researchers identify molecule for detecting parasitic infection in humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Comparing chimp human DNA

(Date:3/30/2015)... , Mar. 26, 2015 Research and Markets ... the "Global Gesture Recognition Market in Automotive Sector ... analysts forecast the Global Gesture Recognition market in Automotive ... the period 2013-2018. Gesture recognition is the ... different gestures of an individual. Gesture recognition technology can ...
(Date:3/24/2015)... PALM BEACH GARDENS, Fla. , March 24, ... of biometric identity management solutions, today announced that ... enabling premium clothing accessory retailer Goorin Bros ... login. The Crossmatch biometrics-based solution secures access to ... customers from the increased risk of data breaches. ...
(Date:3/20/2015)... , Mar. 20, 2015 Research and Markets ... addition of the "India Sensors Market Forecast ... The sensor market is projected to ... Consumer electronics, automotive, industrial and healthcare ... in the country. In addition, adoption of MEMS ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
... chimpanzees likely occurred some 8 million years ago rather ... scientists, a new statistical model suggests. The revised estimate ... closest primate relatives should enable scientists to better interpret ... curator of biological anthropology at the Field Museum, and ...
... Approximately 60,000 pregnant women are hospitalized each year due ... vomiting that endangers their lives and often forces them to ... women with sisters, mothers and grandmothers on either side of ... the risk of HG may be heightened, according to a ...
... led by Teh-hui Kao, professor of biochemistry and molecular biology ... by Professor Seiji Takayama at the Nara Institute of Science ... genes in the petunia plant that acts to prevent it ... to promote breeding with unrelated individuals. In much the same ...
Cached Biology News:New statistical model moves human evolution back 3 million years 2Study shows extreme form of pregnancy-related morning sickness could be genetic 2To prevent inbreeding, flowering plants have evolved multiple genes, research reveals 2To prevent inbreeding, flowering plants have evolved multiple genes, research reveals 3To prevent inbreeding, flowering plants have evolved multiple genes, research reveals 4
(Date:4/24/2015)... 2015 /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ) ... supplier of bio-succinic acid used to produce a ... applications that Bayer MaterialScience has begun commercializing.    ... eco, a series of bio-based waterborne polyurethane ... as 65%.  IMPRANIL ® eco has been ...
(Date:4/24/2015)... -- Navitas Life Sciences is delighted to announce the appointment of ... Services. Shalabh is a proven leader in Life Science consulting ... as well as a Strategy consultant at Accenture. ... ... to welcome Shalabh into this critical role and also as ...
(Date:4/23/2015)... Marshall, MN (PRWEB) April 24, 2015 ... agreement with Advanced Birthright Nutrition® (ABN) for the exclusive ... Milk Cup. The new technology is a new in-line ... swine producers by allowing them to move supplementation milk ... running. , “This technology lets producers get ...
(Date:4/23/2015)... MISSISSAUGA, ON , April 23, 2015 /CNW/ ... major sustainable packaging award from North ... Packaging,s Brandcheck Competitor Comparison won Silver in the ... Awards. The Brandcheck "Competitor Comparison" is ... set of North American and Global peers. This ...
Breaking Biology Technology:Bayer MaterialScience Names BioAmber As Its Supplier For New Product Line - Bio-succinic acid forms backbone of innovative new bio-based polyurethanes for textiles 2Bayer MaterialScience Names BioAmber As Its Supplier For New Product Line - Bio-succinic acid forms backbone of innovative new bio-based polyurethanes for textiles 3Bayer MaterialScience Names BioAmber As Its Supplier For New Product Line - Bio-succinic acid forms backbone of innovative new bio-based polyurethanes for textiles 4Shalabh Kumar Joins Navitas Life Sciences to Lead their Clinical and Regulatory Services Teams 2Ralco Acquires License to Birthright™ Moveable Milk Cup 2
... 2011  According to results from the most recent ... particularly those in the durable goods sector, suffered from ... rising energy and raw materials costs, and falling business ... fall Monitor participants say their businesses are thriving and ...
... Nov. 21, 2011   OrthoAccel® Technologies, Inc. announced ... Micerium S.p.A. based in Avegno for exclusive distribution ... The AcceleDent™ System is ... the United Kingdom in October 2009.  The lightweight appliance, used to ...
... 2011 New Report Added in ResearchMoz Reports ... and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic Surgery to ... GBI Research . GBI ... - Glaucoma and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic ...
Cached Biology Technology:McGladrey Manufacturing and Distribution Monitor® Shows Business Accelerating Despite Concerns About Government Gridlock 2McGladrey Manufacturing and Distribution Monitor® Shows Business Accelerating Despite Concerns About Government Gridlock 3McGladrey Manufacturing and Distribution Monitor® Shows Business Accelerating Despite Concerns About Government Gridlock 4OrthoAccel® Technologies, Inc. Announces Definitive Distribution Agreement in Italy 2OrthoAccel® Technologies, Inc. Announces Definitive Distribution Agreement in Italy 3ResearchMoz: Ophthalmic Devices Market to 2017 - Glaucoma and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic Surgery to Drive the Ophthalmic Surgery Market 2ResearchMoz: Ophthalmic Devices Market to 2017 - Glaucoma and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic Surgery to Drive the Ophthalmic Surgery Market 3ResearchMoz: Ophthalmic Devices Market to 2017 - Glaucoma and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic Surgery to Drive the Ophthalmic Surgery Market 4
RABBIT ANTI HUMAN CYTOCHROME P450 1A1/2 Immunogen: Purified human CYP1A2 expressed in E.Coli ...
... cloning of BAC (100+kb), fosmid (40kb), and ... stability than any othe BAC vector. On ... yields and easy recombinant DNA purification. Available ... (pSMART VC) vectors for the highest insert ...
... Error-free cloning of BAC (100+kb), fosmid ... Greater insert stability than any othe BAC ... for high yields and easy recombinant DNA ... or transcription-free (pSMART VC) vectors for the ...
RABBIT ANTI GLYCINE...
Biology Products: