Navigation Links
Comparing chimp, human DNA

Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. Instead, they may contain DNA sequences that control how gene-coding regions are activated and read.

"The differences between chimps and humans are not in our proteins, but in how we use them," said Katherine Pollard, assistant professor at the UC Davis Genome Center and the Department of Statistics.

Pollard and colleagues at UC Santa Cruz led by David Haussler looked for stretches of DNA that were highly conserved between chimpanzees, mice and rats. Then they compared those sequences to the human genome sequence, to find pieces of DNA that had undergone the most rapid change since the ancestors of chimps and humans diverged about five million years ago.

They found 202 "highly accelerated regions" or HARs, which showed a high rate of evolution between humans and chimps. Only three of those regions contain genes that are likely to encode proteins. The most dramatically accelerated region, HAR1, appears to make a piece of RNA that may have a function in brain development.

DNA, deoxyribonucleic acid, carries the genetic instructions for making a chimp, a human, a tulip or an amoeba. RNA (ribonucleic acid) is an intermediate molecule that transcribes those instructions to make proteins.

The other highly accelerated regions do not appear to code for genes at all, but many are located close to genes involved in controlling when other genes get made, or in growth and development.

"They're not in genes, but they're near genes that do some very important stuff," Pollard said.

Typically, noncoding regions of DNA evolve more rapidly than regions carrying genes, as there is no selective pressure to stop mutations from accumulating. But the human-accelerated regions are highly conserved across the other groups of animals the researchers looked at, suggesting that they do have important
'"/>

Source:University of California - Davis


Page: 1 2

Related biology news :

1. Novel technology detects human DNA mutations
2. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
3. UWs Rosetta software to unlock secrets of many human proteins
4. Genome-wide mouse study yields link to human leukemia
5. Found: Missing sequence of the human Y chromosome
6. Study finds more than one-third of human genome regulated by RNA
7. Molecular machine may lead to new drugs to combat human diseases
8. Sea skate experiment sheds light on human cell transport
9. Mouse brain tumors mimic those in human genetic disorder
10. Zebrafish may hold key to understanding human nerve cell development
11. Yale researchers identify molecule for detecting parasitic infection in humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Comparing chimp human DNA

(Date:5/18/2013)... increasing number of U.S. children are experiencing gastrointestinal ... research presented at Digestive Disease Week (DDW). ... the Cleveland Clinic Children,s Hospital found that obese ... compared to their lean counterparts. The pattern showed ... be correlated to potential complications associated with obesity, ...
(Date:5/17/2013)... the interaction of a group of proteins in the ... identified a new target that could increase cell survival. ... School of Biochemistry and published in the EMBO ... eventually lead to new therapies for stroke and other ... by the team which identified a protein, known as ...
(Date:5/17/2013)... An international team of scientists using ... cell movement inside a living frog embryo in greater ... method to advance biological research and the search for ... and the Karlsruher Institut fr Technologie in Germany, in ... Department of Energy,s Argonne National Laboratory, released the most ...
Breaking Biology News(10 mins):New research identifies risks, interventions for children's GI health 2New research identifies risks, interventions for children's GI health 3SUMO wrestling cells reveal new protective mechanism target for stroke 2New X-ray method shows how frog embryos could help thwart disease 2
... Prospect, IL, USA, 05. October, 2011 Eurofins ... co-operation agreement to combine their expertise in sequencing ... organisms. Integrated Genomics, based in Mount Prospect, Illinois, ... tools and services based on the ERGO(tm) genome ...
... study, scientists explain how they used DNA to identify microbes ... oil spill -- and the particular microbes responsible for consuming ... played a key role in the way bacteria reacted to ... National Academy of Sciences (PNAS) published the results in ...
... To arrange for an interview with a researcher, please contact ... end of each tip. For more information on ORNL and ... our Media Contacts. If you have a general media-related question ... RACING -- Green checkered flag . . . ...
Cached Biology News:Scientists identify microbes responsible for consuming natural gas in Deepwater Horizon spill 2Scientists identify microbes responsible for consuming natural gas in Deepwater Horizon spill 3Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2011 2Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2011 3Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2011 4
(Date:5/20/2013)... 2013 Recognizing exciting and innovative ... to its 2013 Class of Young Professors. ... provide this outstanding international group with more than ... science to meet global challenges.     , The DuPont ... young and untenured research faculty working in areas ...
(Date:5/20/2013)... In Early 2013, Dr. Ritchie ... related illnesses , announced his vision for creating a ... his protocol for treating Chronic Inflammatory Response Syndrome (CIRS). ... to achieve certification in the Shoemaker Protocol. , ... the Shoemaker Protocol in other parts of the country, ...
(Date:5/19/2013)... The JM Internet Group (web: jm-seo.org), a leader ... that the company's YouTube channel on SEO tips ... YouTube. The company uses YouTube as a way to ... for small businesses with much success. , "I love ... for their SEO strategies", explained Jason McDonald, director of ...
(Date:5/17/2013)... Mechanicsburg, PA (PRWEB) May 17, 2013 ... with ramp/soak capabilities. The 5R6-900 temperature controller has many ... can be plugged into the wall as a self-contained ... power supply. This distinctive detail makes the device unique, ... , The controller can also be used universally, which ...
Breaking Biology Technology:DuPont Celebrates Scientific Innovation by Recognizing Young Professors 2DuPont Celebrates Scientific Innovation by Recognizing Young Professors 3Dr. Ritchie Shoemaker Certifies Third Physician in His Treatment Protocol for Chronic Inflammatory Response Syndrome (CIRS) 2YouTube Channel on SEO Tips Surpasses 175,000 Views, Announces JM Internet Group 2New Temperature Control Products Announced by Oven Industries Inc. 2
... 14 For 88 percent of,companies, front-line and ... cover a variety of development skills but focus,strongly ... Yet only half of executive-level sales leaders ... leadership development and,training, according to a member-driven research ...
... April 14 eResearchTechnology,Inc. (eRT), (Nasdaq: ... today their,alliance to provide integrated Cardiac Safety ... worldwide., eResearchTechnology is a leading provider ... other services,to the pharmaceutical, biotechnology, medical device, ...
... Corporation,(Pink Sheets: PHCP) (the "Company") clarified today that ... connection with,market transactions and are a valid representation ... This clarification was issued in response to,information from ... firms,will not negotiate Phlo common stock certificates issued ...
Cached Biology Technology:Developing Sales Leaders: Benchmarks Reveal Tactics that Will Propel Your Business 2eResearchTechnology, Inc. and nSpire Health, Inc. Form Alliance to Deliver Integrated Cardiac Safety and Pulmonary Clinical Trial Services 2eResearchTechnology, Inc. and nSpire Health, Inc. Form Alliance to Deliver Integrated Cardiac Safety and Pulmonary Clinical Trial Services 3Phlo Clarifies That Pre-Reverse Split Certificates Are Negotiable in Market Transactions 2
Recalibration of HL-2000-CAL products...
Human HVEM/TNFRSF14 Allophycocyanin MAb (Clone 94801)...
Enodgenous alkaline phosphotase inhibitor. Levamisole solution is supplied in concentrated form (20x). The final concentration of levamisole in the substrate solution will be 1 mM....
X-gal,1g...
Biology Products: