Navigation Links
Commonly used antidepressants may also affect human immune system

, between immune cells that is normally only found between neurons," Ahern said.

In addition to Ahern, Peta Connell, Ph.D., from the Robarts Research Institute in Canada, was also a co-lead researcher on the study. Scientists from the Robarts Research Institute also contributed to the work.

In the brain, serotonin transmission between neurons is associated with feelings of pleasure, mood, and appetite, and the class of antidepressants known as SSRIs keeps serotonin active within the synaptic spaces between neurons, enhancing the chemical's positive effects. Unlike in the brain, which uses chemical messengers to communicate between nerve cells, the immune system is believed to "converse" through physical contact -- one type of immune cell touches another, setting off a response.

Specifically, "antigen presenting cells" display their antigens (bits of a foreign invader) to T-cells, and a resulting physical coupling between the antigens and the T-cells will prompt the T-cells to divide and expand in population, triggering an immune response designed to destroy the invader. This process may take hours.

What the Georgetown researchers found, however, is that dendritic cells -- the most powerful of the antigen-presenting cells and the ones that can find invaders that have never infected the body and "educate" the immune system to fight them -- also use serotonin to quickly excite a T-cell response. They discovered that these dendritic cells can rapidly secrete serotonin, which activates serotonin receptors on certain types of T-cells.

"In addition to the physical contact, it surprised us to find that these immune cells also have machinery to take up serotonin and to secrete it in an excitatory manner," Ahern said. "The point behind this transmission is not entirely clear, but it appears to be an additional way of stimulating a T cell response."

Drugs that block serotonin reuptake "likely change some of the parameters of T-ce
'"/>

Source:Georgetown University Medical Center


Page: 1 2 3

Related biology news :

1. Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
2. In SAD patients, autumn antidepressants can prevent winter depression
3. Suicide risk does not increase when adults start using antidepressants, study finds
4. Cytoplasm affects the number of vertebrae in carp-goldfish clones
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. A new study examines how shared pathogens affect host populations
7. Researchers discover chemical compounds that affect plant growth
8. WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
9. Road salt affects mitigation wetlands
10. Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans
11. Exercise training in ordinary people affects the activity of 500 genes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Commonly used antidepressants may also affect human immune system

(Date:12/24/2014)... NEW YORK , Dec. 23, 2014  Since its launch in ... of people to eliminate the pain of trying to remember ... their own biometrics fused to their smartphones. To assist people ... Labs , the company that created 1U and focuses on ...
(Date:12/22/2014)... 22, 2014  The 2014 Holiday Season may be the ... Intelligence reports that the long anticipated floodgates for consumer ... demand for smart phones, tablets, and wearable mobile devices ... 2.5 billion users with nearly 4.8 billion biometric devices ...
(Date:12/19/2014)... , Dec. 18, 2014  23andMe, Inc., the leading personal genetics ... fine-scale differences in genetic ancestry of individuals from across ... first arrived more than four hundred years ago, ... place for peoples from different continents. This study illuminates how ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4
... State University researcher is exploring a new method of ... is more effective and reliable than using eye drops. ... clinical sciences at Iowa State,s College of Veterinary Medicine, ... method of implanting biodegradable medicine into the tissue surrounding ...
... mechanism has been discovered in a microorganism that thrives in ... key processes in human cells, and in a better understanding ... study is published today in the online version the American ... group at the Department of Molecular Evolution at Uppsala University ...
... chemicals, such as methylmercury can cause harm at levels ... evidence in the International Journal of Environment and ... approach to this and similar compounds to protect unborn ... the Department of Environmental Health at Harvard School of ...
Cached Biology News:Iowa State researcher develops new treatment method for canine eye diseases 2Iowa State researcher develops new treatment method for canine eye diseases 3New cell division mechanism discovered 2Methylmercury warning 2
(Date:1/23/2015)... 2015 Portal Solutions , a technology ... Microsoft Office 365 and SharePoint platforms , today announces ... for being one of the region’s fastest-growing mid-sized companies based ... , “To be recognized a second year in a ...
(Date:1/22/2015)... 22, 2015 GEA Niro Soavi the ... laboratory homogenizer, the PandaPLUS 2000, which is ideal for ... and cell disruption . This compact laboratory homogenizer ... juices, liquid food, food additives and ingredients as well ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Protocol Networks ... The growing team of brand-neutral, independent consultants, Protocol Networks ... Rogers explained that over the years, his company has ... Moroso, Town of Plainfield, as well as others. With ...
(Date:1/22/2015)... 2015 Dr. Greg Leyer of UAS Labs ... Natural Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... continuing education conference for health care professionals. This year’s pre-conference ... of probiotics in health. Dr. Leyer spoke about the emerging ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... , , , Multiporator / Electroporator 2510 , , , , , ... Transformation Protocol , Protocol No. 4308 915.501 04/2002 , ... , , , Microorganism , ... Cell type , Bacteria, gram negative, ...
... , , , , , , Multiporator / Electroporator 2510 , , ... , Transformation Protocol , Protocol No. ... , , , , , , ... , , Cell type , ...
... Eppendorf's Perfectprep Plasmid , Mini Kit , ... , James Griffith and Kim Vollmer , ... Vollmer, Brinkmann Instruments, Biosytems Application Lab, Westbury, , NY , , ... , Cosmids are commonly used vectors in the lab, ...
Cached Biology Technology:Actinomyces viscosus 2Actinobacillus pleuropneumoniae 2Isolation of Cosmids using Eppendorf's Perfectprep Plasmid , Mini Kit 2Isolation of Cosmids using Eppendorf's Perfectprep Plasmid , Mini Kit 3Isolation of Cosmids using Eppendorf's Perfectprep Plasmid , Mini Kit 4Isolation of Cosmids using Eppendorf's Perfectprep Plasmid , Mini Kit 5
... in your samples with eArray and Agilents custom ... your own microarray designs that meet your specific ... receive delivery of your arrays in weeks, anywhere ... array creation application tool that enables you to ...
... the demands of the routine trace metal ... reliable, robust and simple to use instrumentation. ... the most challenging sample matrices found in ... to the toughest analytical challenges found in ...
Polio component type I...
Choriongonadotropin (human, hCG)...
Biology Products: