Navigation Links
Common parasitic infection leads to increased risk for HIV infection

A new study shows a significantly increased risk of HIV infection among women with a common sexually transmitted disease, trichomoniasis. Although studies have been undertaken in the past to show the link between sexually transmitted infections and susceptibility to HIV, the study published in the March 1 issue of The Journal of Infectious Diseases, now available online, is one of the first to demonstrate a statistically significant association between trichomoniasis and HIV infection.

Trichomoniasis, caused by the parasite, Trichomonas vaginalis infects more than 170 million people worldwide each year. On its own, it usually does not cause serious complications. Some men may experience a mild burning sensation or discharge. Some women may have a frothy, strong-smelling yellow green discharge, and may feel discomfort during intercourse and urination, as well as itching of the genital area. Lower abdominal pain occurs in rare cases.

The study, conducted by R. Scott McClelland, MD, MPH, and colleagues at the University of Washington in Seattle, the University of Nairobi, and the Coast Provincial General Hospital in Kenya, followed 1,335 HIV-seronegative women over the span of 11 years. Because infection with T. vaginalis is common, even a modest increase in vulnerability to HIV acquisition as a result could mean a substantial attributable risk for HIV infection overall. According to McClelland, "the modest increase in risk makes it important that studies are either very large or of long duration in order to demonstrate such an effect."

Their results showed a 1.5-fold increased risk of HIV infection among women with trichomoniasis. "What this means is that a woman with trichomoniasis is at about fifty percent greater risk for acquiring HIV than a woman without trichomoniasis, after adjusting for other differences between the women such as differences in the rates of condom use, number of sex partners, etc." said McClelland.

The study pointed to several reasons why vaginal trichomoniasis could possibly lead to an increased risk of HIV acquisition. Trichomoniasis can cause tiny areas of bleeding within mucous membranes that could provide a physical pathway for HIV infection. Also, the study noted, the T. vaginalis parasite has been shown to break down an enzyme that blocks HIV attachment to cells.

The findings from this study provide support for prevention and treatment of sexually transmitted diseases such as trichomoniasis as important strategies for preventing HIV infection. As a next step, McClelland suggested that "comprehensive strategies for reducing vaginal infections and addressing potentially harmful intravaginal practices such as douching, washing, or placing traditional substances in the vagina should be developed and evaluated in clinical trials as possible female-controlled HIV prevention interventions."
'"/>

Source:Infectious Diseases Society of America


Related biology news :

1. Its not all genetic: Common epigenetic problem doubles cancer risk in mice
2. Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
3. Men Estimate Mens Risks Of Common Disorders Higher Than Women Do, And Vice Versa
4. Use of Antibiotics for Acne May Increase Risk of Common Illness
5. Common viruses may cause cancer
6. Common alternative treatment for liver disease is found to be ineffective
7. Common molecular signature identified in solid tumors
8. Common bacteria pirate natural mechanism to get inside cells
9. Commonly used antidepressants may also affect human immune system
10. Common practices at petting zoos put visitors at risk
11. Common enzyme is a key player in DNA repair

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... BETHESDA, Md. , June 22, 2016  The American ... by Trade Show Executive Magazine as one of ... Summit on May 25-27 at the Bellagio in ... based on the highest percentage of growth in each of ... number of exhibiting companies and number of attendees. The 2015 ...
(Date:6/16/2016)... June 16, 2016 The ... expected to reach USD 1.83 billion by 2024, ... Research, Inc. Technological proliferation and increasing demand in ... expected to drive the market growth. ... The development of advanced multimodal techniques for ...
(Date:6/3/2016)... 3, 2016 Das ... Nepal hat ein 44 ... geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, ... Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte ... Januar teilgenommen, aber Decatur wurde als konformste ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... June 24, 2016 Epic Sciences unveiled ... cancers susceptible to PARP inhibitors by targeting homologous ... (CTCs). The new test has already been incorporated ... multiple cancer types. Over 230 clinical ... response pathways, including PARP, ATM, ATR, DNA-PK and ...
(Date:6/23/2016)... ... June 23, 2016 , ... UAS LifeSciences, one ... of their brand, UP4™ Probiotics, into Target stores nationwide. The company, which has ... add Target to its list of well-respected retailers. This list includes such fine ...
(Date:6/23/2016)... , June 23, 2016 Houston Methodist ... the Cy-Fair Sports Association to serve as their ... agreement, Houston Methodist Willowbrook will provide sponsorship support, ... connectivity with association coaches, volunteers, athletes and families. ... the Cy-Fair Sports Association and to bring Houston ...
(Date:6/23/2016)... June 23, 2016   EpiBiome , a precision ... million in debt financing from Silicon Valley Bank (SVB). ... and to advance its drug development efforts, as well ... "SVB has been an incredible strategic partner ... a traditional bank would provide," said Dr. Aeron ...
Breaking Biology Technology: