Navigation Links
Clinical trial to test stem cell approach for children with brain injury

A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow starting early next year at The University of Texas Medical School at Houston and Memorial Hermann Children's Hospital.

The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic stem cells.

"There is no reparative treatment for traumatic brain injury," said principal investigator Charles Cox, M.D., The Children's Fund, Inc. Distinguished Professor in Pediatric Surgery and Trauma at the medical school. "All we can do now is try to prevent secondary damage by relieving pressure on the brain caused by the initial injury."

Unlike bone, muscle and other organs, the brain does not repair itself effectively. Traumatic brain injury victims can regain some function through rehabilitation. Studies show between 15 and 25 percent of children suffering severe traumatic brain injury die, and survivors of even moderate injury often are devastated for life.

Approved by the U.S. Food and Drug Administration and the university's Committee for the Protection of Human Subjects (CPHS), the clinical trial builds on laboratory and animal research indicating that bone-marrow derived stem cells can migrate to an injured area of the brain, differentiate into new neurons and support cells, and induce brain repair.

"This would be an absolutely novel treatment, the first ever with potential to repair a traumatically damaged brain," said James Baumgartner, M.D., associate professor of pediatric neurosurgery and co-principal investigator on the project.

As a Phase I clinical trial, the project's first emphasis is to establish the safety of the procedure, with a secondary goal of observing possible therapeutic effects.

Cox and Baumgartner have permission to recruit 10 head injury patients to the study between th
'"/>

Source:University of Texas Health Science Center at Houston


Page: 1 2 3

Related biology news :

1. International trial of two microbicides begins
2. Use of PET can reduce, may eliminate more strenuous drug development trials with animals
3. HIV vaccine trial breaks ground for future research
4. Roche clinical trial registry and results database launched
5. NIAID begins clinical trial of West Nile virus vaccine
6. Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT
7. Compound might defeat African sleeping sickness, clinical trial beginning this month
8. Why were the HIV prevention trials in commercial sex workers abandoned?
9. Neurologix announces positive results of gene therapy clinical trial in Parkinsons disease
10. Industrial contaminants spread by seabirds in High Arctic, new Canadian study shows
11. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clinical trial test stem cell approach for children with brain injury

(Date:8/31/2014)... for sniffing the highly infectious bacteria C. diff ... been developed by a team at the University of ... has demonstrated that it is possible to identify the ... lead to rapid diagnosis of the condition., What is ... to identify different strains of the disease simply from ...
(Date:8/31/2014)... are not busy attacking us, germs go after each ... spell disaster for the infected microbes: Sometimes viruses actually ... say, expand its diet or better attack its own ... an immune system would robotically destroy anything it recognized ... University have now revealed that one variety of the ...
(Date:8/31/2014)... Nature Climate Change , suggests that if current trends ... the global targets for total greenhouse gas (GHG) emissions in ... think carefully about the food we choose and its environmental ... just one of a number of actions that need to ... is enough food for all. , As populations rise ...
Breaking Biology News(10 mins):Scientists develop 'electronic nose' for rapid detection of C. diff infection 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 3Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4
... of Defence (MINDEF) and the Nanyang Technological University (NTU) ... strengthen Singapore,s defence science and technology research and development ... by inking a Memorandum of Understanding (MOU) at the ... the setting up of the Temasek Research Fellowship and ...
... Pharmaceutical Scientists (AAPS) is a professional, scientific society ... government and other research institutes worldwide. Founded in ... the exchange of knowledge among scientists to enhance ... scientific programs, on-going education, information resources, opportunities for ...
... tropical butterfly that potentially makes it able to distinguish between ... from the University of Bristol, UK. The team ... detection of predators, in particular birds. The Blue Morpho ... America, are more famous for their amazing wing colouration and ...
Cached Biology News:MINDEF, NTU join hands to boost Singapore's defense R&D capabilities 2
(Date:8/30/2014)... The Global and China Electrical ... study on the current state of the Electrical ... The report provides a basic overview of the ... Global market analysis and Chinese domestic market analysis ... trends and competitive landscape of the market. A ...
(Date:8/29/2014)... According to a new market report published ... market was valued at USD 3,754.6 million in 2012 and ... 2019at a CAGR of 5.9% from 2013 to 2019. , ... is afflicted by bone and joint disorders, and this number ... has and will continue to increase the demand for orthobiologics. ...
(Date:8/29/2014)... Three Lawrence Livermore researchers have ... Production R&D Award for their research in ... sunlight. , Shared with collaborators from the National ... Nevada, Las Vegas (UNLV), the award recognizes the ... solar-hydrogen production and corrosion processes. , These models ...
(Date:8/28/2014)... SPIE Fellow Glenn Boreman, Professor and ... and Director of the Center for Optoelectronics and Optical ... and co-founder and Chairman of the Board of Plasmonics, ... Vice President of SPIE, the international society for optics ... recent election results at the Annual General Meeting of ...
Breaking Biology Technology:Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3Livermore Team Awarded for Hydrogen Production Research 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... A new, one-year, double-blind controlled clinical study shows that ... risk in postmenopausal women with type 2 diabetes [1] ... Peter J. Curtis, Ph.D., et al , funded by ... Ltd., Israel, and Barry Callebaut, the world,s leading manufacturer of ...
... polymers will offer unprecedented control over the final polymer structure ... study published last week in the prestigious journal Nature ... in Sydney and the University of Warwick in the UK ... a combination of segregation and templating a pair of ...
... integrated circuits are found in many applications, from large ... integration is due in part to the semiconductor industry,s ... for decades. However, while silicon-based circuits continue to ... Law the prediction that the number of transistors ...
Cached Biology Technology:New Findings of Daily Consumption of Soy Isoflavones and Cacao-Flavonoids in Diabetes Type 2 Patients 2New Findings of Daily Consumption of Soy Isoflavones and Cacao-Flavonoids in Diabetes Type 2 Patients 3Bio-inspired polymer synthesis enhances structure control 2Next-generation nanoelectronics: A decade of progress, coming advances 2Next-generation nanoelectronics: A decade of progress, coming advances 3
Request Info...
SHEEP ANTI BOVINE BETA-LACTOGLOBULIN A...
Rabbit polyclonal to Somatostatin 28 ( Abpromise for all tested applications). entrezGeneID: 6750 SwissProtID: P61278...
... an essential component of the COP9 signalosome ... cellular and developmental processes. The CSN complex ... (Ubl) conjugation pathway by mediating the deneddylation ... ligase complexes. The complex is also involved ...
Biology Products: