Navigation Links
Clinical trial to test stem cell approach for children with brain injury

A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow starting early next year at The University of Texas Medical School at Houston and Memorial Hermann Children's Hospital.

The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic stem cells.

"There is no reparative treatment for traumatic brain injury," said principal investigator Charles Cox, M.D., The Children's Fund, Inc. Distinguished Professor in Pediatric Surgery and Trauma at the medical school. "All we can do now is try to prevent secondary damage by relieving pressure on the brain caused by the initial injury."

Unlike bone, muscle and other organs, the brain does not repair itself effectively. Traumatic brain injury victims can regain some function through rehabilitation. Studies show between 15 and 25 percent of children suffering severe traumatic brain injury die, and survivors of even moderate injury often are devastated for life.

Approved by the U.S. Food and Drug Administration and the university's Committee for the Protection of Human Subjects (CPHS), the clinical trial builds on laboratory and animal research indicating that bone-marrow derived stem cells can migrate to an injured area of the brain, differentiate into new neurons and support cells, and induce brain repair.

"This would be an absolutely novel treatment, the first ever with potential to repair a traumatically damaged brain," said James Baumgartner, M.D., associate professor of pediatric neurosurgery and co-principal investigator on the project.

As a Phase I clinical trial, the project's first emphasis is to establish the safety of the procedure, with a secondary goal of observing possible therapeutic effects.

Cox and Baumgartner have permission to recruit 10 head injury patients to the study between th
'"/>

Source:University of Texas Health Science Center at Houston


Page: 1 2 3

Related biology news :

1. International trial of two microbicides begins
2. Use of PET can reduce, may eliminate more strenuous drug development trials with animals
3. HIV vaccine trial breaks ground for future research
4. Roche clinical trial registry and results database launched
5. NIAID begins clinical trial of West Nile virus vaccine
6. Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT
7. Compound might defeat African sleeping sickness, clinical trial beginning this month
8. Why were the HIV prevention trials in commercial sex workers abandoned?
9. Neurologix announces positive results of gene therapy clinical trial in Parkinsons disease
10. Industrial contaminants spread by seabirds in High Arctic, new Canadian study shows
11. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clinical trial test stem cell approach for children with brain injury

(Date:11/21/2014)... 2014 C-Labs LLC, a leading provider of ... (IoT), today announced the appointment of John Traynor ... a strategic advisor to the firm, Mr. Traynor will ... is based out of the C-Labs office in ... Chris Muench , Chief Executive Officer. Photo ...
(Date:11/18/2014)... , Nov. 18, 2014  The Secure Identity ... Association today jointly announce the formation of The ... of its Identity and Biometric Entry and ... Framework received official support from BORDERPOL, the international ... improve and provide expertise regarding border security, traveler ...
(Date:11/18/2014)... BETHESDA, Md. , Nov. 17, 2014 The ... European and U.S. regulatory agencies will speak and at least ... Quality Metrics Conference at the Omni Shoreham Hotel in ... is pleased once again to have significant support from the ... and Europe in our effort to ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... become more educated, studies have demonstrated that they tend to ... nutrients. They also pay more. In a study published in ... American Dietetic Association , researchers from the University of Washington ... of 164 adults in the Seattle, Washington area. The ...
... plants are constantly confronted with adverse environmental conditions, lowering ... use specialized signals, called stress hormones, to sense difficult ... Of the various stress hormones, abscisic acid ... last 30 years as the key hormone that helps ...
... readily available to health officials and businesses, a Purdue ... amounts of melamine in infant formula. Using infrared ... professor of food science, was able to detect melamine ... about five minutes or less. Melamine, a synthetic chemical ...
Cached Biology News:People of higher socioeconomic status choose better diets -- but pay more per calorie 2Synthetic chemical offers solution for crops facing drought 2Synthetic chemical offers solution for crops facing drought 3Researcher: Lasers used to detect melamine in baby formula 2
(Date:12/24/2014)... , December 23, 2014 ... Algeria , out today and available for free download ... actors driving change and growth in the sector today. ... scored notable successes has been in developing a homegrown pharmaceutical ... percent local production still remains some way off. A cursory ...
(Date:12/22/2014)... ROCKVILLE, Md. , Dec. 22, 2014 ... MKT: SYN), a developer of pathogen-specific therapies ... focus on protecting the microbiome, today announced ... a Phase 1a clinical trial of SYN-004, ... the prevention of Clostridium difficile (C. ...
(Date:12/22/2014)... 2014 The American Journal ... original research, reviews and editorials addressing developments and ... today published a provocative article exploring the role ... and potential treatment of prostate cancer. , ... proposes the possibility that there could be a ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one ... of Nick Maroulis, Pharm.D. to the newly created position ... In this position, Dr. Maroulis will continue to manage ... of our multi-site pharmacies as the company expands. Dr. ... that time he has served in many different capacities ...
Breaking Biology Technology:PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2
... - Ondine Biopharma Corporation,(TSX: OBP; AIM: OBP), ... announced that its Chief Technology,Officer, Dr. Nicolas ... 28th Annual,Canaccord Adams Global Growth Conference at ... 12th, 2008 at 1:00 p.m. Eastern Time., ...
... has launched a commercial biorepository service, bioVAULT, which stores, manages ... scientific and pharmaceutical companies investigating new drug and diagnostic development. ... ... 5, 2008 -- XTELL announced today the launch of its ...
... seeking financing/strategic ... alternatives, ... announced today that the Company is focusing its,day-to-day operations exclusively on ... Company,s remaining cash,resources, the Company,s employees were released from employment, except,for ...
Cached Biology Technology:Ondine to Present at Canaccord Adams 28th Annual Global Growth Conference 2XTELL Launches its Commercial Biorepository Services for Research and Pharmaceutical Companies 2Arbios Announces It Has Suspended Operations 2Arbios Announces It Has Suspended Operations 3Arbios Announces It Has Suspended Operations 4Arbios Announces It Has Suspended Operations 5
... Competitor Assay Kits are ideal for ... binding compounds using fluorescence polarization (FP) ... of glutathione transferase to the ligand ... [PR-LBD(GST)] and a proprietary, fluorescently-tagged progesterone ...
... vectors combine the proven features of the ... and provides all of the benefits and ... vector backbone. The pTriEx vectors have been ... genes in all three expression systems. In ...
Rabbit polyclonal to Shigella Immunogen: Mixture of S. boydii, S. flexneri & S. dysenteriae....
... Cell Identification Kit. ALDEFLUORs ... substrate for the enzyme ... is highly expressed in ... making ALDH an extremely ...
Biology Products: