Navigation Links
Circulating stem cells play small role in lung repair

Circulating stem cells play a minor role in repairing lung damage, according to a team of scientists who used male and female chromosomal differences to analyze the repair process in lung transplant patients.

Reporting in today's edition of the journal Transplantation, lead author Dani Zander, M.D., of The University of Texas Medical School at Houston, and colleagues at the University of Florida College of Medicine found that less than 1 percent of a certain type of reparative lung stem cell originated in the bone marrow of the transplant recipient.

"It's possible in the future that circulating stem cells could be augmented to play a greater role in lung repair ?and people are looking at ways to do that. We found that the bulk of stem cell contribution to the repair process belongs to those stem cells normally found in the lungs rather than to circulating stem cells," said Zander, who is professor and vice chair of pathology and laboratory medicine.

Stem cells are produced during adulthood in the bone marrow, where some remain while others circulate in the blood stream. Their main function is to produce all of the elements of blood. Some studies show that circulating stem cells are capable of diffentiating into other types of tissue, including lung tissue, Zander said, and this study provides evidence of differentiation.

Researchers examined lung biopsy specimens from seven male transplant recipients who had received lungs from female donors. They analyzed the origins of type II pneumocytes, a stem cell involved in the complex processes of lung repair, found in the lung tissue. Donor lungs come with their own type II pneumocytes, which in this case have two X chromosomes. Cells produced by the recipient's bone marrow have an X and a Y (male) chromosome.

Lung transplant recipients are vulnerable to pulmonary injury from infections, rejection of the transplanted lung, ischemia, and other factors that damage the alveoli ?tiny holl
'"/>

Source:University of Texas Health Science Center at Houston


Page: 1 2 3

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Spleen may be source of versatile stem cells
3. Researchers discover way to make cells in the eye sensitive to light
4. Priming embryonic stem cells to fulfill their promise
5. Lack of enzyme turns fat cells into fat burners
6. Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
7. Elusive HIV shape change revealed; Key clue to how virus infects cells
8. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
9. Enzyme allows B cells to resist death, leading to leukemia
10. Scientists rid stem cell culture of key animal cells
11. Genetically modified natural killer immune cells attack, kill leukemia cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Circulating stem cells play small role lung repair

(Date:8/27/2014)... 27, 2014  WaferGen Bio-systems, Inc. (NASDAQ: WGBS) today ... public offering of units of common stock and warrants ... proceeds of $20 million, prior to deducting underwriting discounts ... The shares and warrants are immediately separable and will ... in the offering consists of 2,000 shares of common ...
(Date:8/27/2014)... researchers have identified a gene that could help scientists ... protein in the cell membrane of plants that senses ... conservation machinery accordingly. , "It,s similar to a ... at Duke. , The findings, which appear Aug. ... it easier to feed the world,s growing population in ...
(Date:8/27/2014)... neural circuits in the brain of mice, scientists ... The research, led by Howard Hughes Medical Institute ... Technology (MIT), reveals that the connections between the ... about an experience and the part of the ... experience are malleable. , Altering those connections ...
Breaking Biology News(10 mins):WaferGen Bio-Systems Announces Successful Completion of Public Offering Raising $20 Million 2WaferGen Bio-Systems Announces Successful Completion of Public Offering Raising $20 Million 3Water 'thermostat' could help engineer drought-resistant crops 2Researchers change the emotional association of memories 2Researchers change the emotional association of memories 3Researchers change the emotional association of memories 4
... long speculated that high diabetes rates among Native Americans may ... ancient hunter-gatherers store fat for survival during famine may contribute ... a new analysis of fossil feces from an Arizona cave ... do with famine and much more to do with the ...
... FRANCISCO, July 24, 2012 -- The San Francisco State ... a deadly fly parasite want people across the United ... their own backyards. Today SF State Professor of ... Department of Biology and the Center for Computing for ...
... diabetes study at the University of Leicester has discovered that ... origin) have higher levels of blood sugar than white Europeans ... The study of 4,688 white Europeans and 1,352 South Asians ... of Leicester, Department of Cardiovascular Sciences, and was published in ...
Cached Biology News:Feces fossils yield new insights into ancient diets and 'thrifty genes' 2Feces fossils yield new insights into ancient diets and 'thrifty genes' 3Citizen scientists needed for SF State's 'ZomBee Watch' 2
(Date:8/27/2014)... MSC , a healthcare performance improvement company advancing clinical ... Mary Beth Loesch to President and CEO. ... companies for rapid growth and market expansion, Loesch joined ... Development and Healthcare. In that role, she oversaw MSC,s ... corporate strategy and marketing. Previously, Loesch served as Senior ...
(Date:8/27/2014)... DUBLIN , Aug. 27, 2014 ... of the "Global Lactic Acid  (Biodegradable Polymer, ... - Trends & Forecasts to 2019" report ... the simplest hydroxyl-carboxylic acid with an asymmetrical carbon ... in the biodegradable polymer, food and beverage, personal ...
(Date:8/27/2014)... , Aug. 27, 2014 Guggenheim Securities, the ... today announced the hiring of veteran equity analyst Charles ... analyst. Mr. Butler will focus on the biotech/biopharma sector. ... a wealth of experience and a broad network of ... Senior Managing Director and Head of Equities at Guggenheim ...
(Date:8/27/2014)... Aug. 27, 2014 Research and Markets ... Isotope Ratio Mass Spectrometer Industry Report 2014" report ... Isotope Ratio Mass Spectrometer Industry Report 2014 is a ... the global isotope ratio mass spectrometer industry. ... including definitions, classifications, applications and industry chain structure. The ...
Breaking Biology Technology:MSC names Mary Beth Loesch President and CEO 2Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2Guggenheim Securities Hires Analyst Charles "Tony" Butler to Expand Healthcare Coverage 2Global Stable Isotope Ratio Mass Spectrometer Industry Report 2014 2
... in 2009 is expected to grow at 8 ... has contributed to a significant shift in the ... Malaysia.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )Dr Pawel Suwinski, Senior Consultant ... the Malaysian healthcare companies are not going to ...
... as well as hundreds of other award winning programs now available at ... ... -- Stream the Bard, James Burke,s Connections, Jacob Bronowski,s Ascent of Man, ... ambrosedigital.com ., , , , ,The collection includes The BBC ...
... in its,ongoing commitment to return value to shareowners, Monsanto Company,(NYSE: ... Directors declared a 10 percent,increase in the quarterly dividend on ... per share. The dividend is payable on April 24, 2009 ... "As we have often said, when farmers succeed ...
Cached Biology Technology:Malaysian Healthcare Industry Is in Good Shape 2Malaysian Healthcare Industry Is in Good Shape 3New Video Streaming Site Created by Ambrose Video Publishing 2New Video Streaming Site Created by Ambrose Video Publishing 3Monsanto Board Approves 10 Percent Dividend Increase 2
IHC Polymer Detection Kit (Rabbit DAB)150 slides...
...
Bovine Serum...
Healthy animals 10-32 weeks of age, mixed gender and breed; collected on wet ice following USDA guidelines, using Alsevers solution at 1:2 dilution...
Biology Products: