Navigation Links
Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

ickle cell disease).

Because blood from the normal, healthy donors contained 1,200 to 155,000 sjTREC copies per milliliter of blood, the investigators chose 1,200 as the lowest end of the normal range for sjTRECs.

The team found that transplant recipients who had more than 1,200 copies of sjTREC in each milliliter of their blood before transplantation were more likely than patients with fewer copies to experience successful reconstitutions of their T cell populations. In patients with fewer than 1,200 copies per milliliter, the transplantation was likely either to fail or be significantly slow in reconstructing the T cell population.

"This is the first demonstration that high levels of sjTREC in a potential stem cell recipient can predict that their thymus will successfully reconstitute their T cell population using donated stem cells," said Xiaohua Chen, Ph.D., first author of the Blood article. "This kind of information should help physicians improve their ability to manage individual patients by predicting how they will respond to stem cell transplants."

Other authors of this study are Raymond Barfield, Ely Benaim, Wing Leung, James Knowles, Dawn Lawrence, Mario Otto, Sheila A. Shurtleff, Geoffrey A. M. Neale, Frederick G. Behm and Victoria Turner.

###

This work was supported in part by the Assisi Foundation of Memphis and ALSAC.

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tennessee, St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more
'"/>

Source:St. Jude Children鈥檚 Research Hospital


Page: 1 2 3 4

Related biology news :

1. Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis
2. Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients
3. Chromosome Deletion Predicts Aggressive Neuroblastoma
4. Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
5. Analysis Of Human Genome To Predict The Development Of Illnesses
6. Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
7. Predicting success
8. Predicting chemotherapy outcome
9. Predicting successful outcomes in living-donor liver transplants
10. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
11. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Circles DNA Might Help Predict Success Stem Cell Transplantation

(Date:9/16/2014)... tree species has its own bacterial identity. That,s the ... other institutions who studied the genetic fingerprints of bacteria ... island. , "This study demonstrates for the first time ... different ecological strategies possess very different microbial communities on ... former postdoctoral researcher in the UO,s Institute of Ecology ...
(Date:9/16/2014)... A complex web of interaction between viruses, bacteria, ... by a growing international collaboration between Matthew Sullivan, ... of Ecology and Evolutionary Biology and Steven Hallam ... Canada. , "Bacteria are drivers of nutrient ... said. "As the climate is changing, so are ...
(Date:9/16/2014)... extravagant, colorful tail feathers in courtship of a peahen. ... camera developed by an engineer at Washington University in ... choose their mates based on a similar display. , ... used a bioinspired polarization camera developed by Viktor Gruev, ... Washington University, to make the discovery. His camera has ...
Breaking Biology News(10 mins):Microbiome research shows each tree species has a unique bacterial identity 2New research decodes virus-host interactions in ocean dead zones 2New research decodes virus-host interactions in ocean dead zones 3Camera developed at WUSTL sheds light on mate choice of swordtail fish 2
... Nov. 9, 2007 Researchers at Childrens Hospital of ... currently underway to study the effectiveness of oral insulin in ... people at risk for the disease. The researchers want ... or delay the onset of type 1 diabetes in relatives ...
... Flip through the 133 page record of the 2006-2007 activities ... and youll see why they recently took home the nations ... toss fundraiser. Youll find the detailed lesson plans that ... to 75 fifth grades at Spreckels elementary school last year. ...
... helping an effort to eradicate malaria, the mosquito-borne disease ... Researchers at the National Institute of Standards and Technology ... a young company create weakened, harmless versions of the ... to create a new type of vaccine that shows ...
Cached Biology News:Children's Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes 2UC-San Diego Engineering Honor Society wins most outstanding chapter award 2Bug-Zapper: A dose of radiation may help knock out malaria 2
(Date:9/16/2014)... September 16, 2014 CIRTEC Medical Systems’ ... Highley as CEO of CIRTEC. , “I am ... for the Company.” noted Brian Highley. “The company has ... sustaining strong organic growth over the past two years. ... continuing to improve and expand the services Cirtec offers ...
(Date:9/16/2014)... 16, 2014   Synthetic Biologics, Inc. ... anti-infective biologic and drug programs targeting specific pathogens ... completion of the Company,s Investor Day in ... irritable bowel syndrome (IBS) program, including its novel, ... In the keynote presentation, Mark Pimentel ...
(Date:9/16/2014)... Arizona (PRWEB) September 16, 2014 ... develops safe and effective products to treat patients ... use of a proprietary SPACE™ Technology Platform announced ... and President will present at the White Hat ... at the Hyatt Regency Phoenix. In addition, ...
(Date:9/16/2014)... BARBARA, Calif. , Sept. 16, 2014 /PRNewswire-iReach/ ... Strength index (BMSi) test identifies patients with bone ... cannot.  Over 160 million people worldwide are at ... detected by today,s standard bone strength test, the ... the 2014 American Society for Bone and Mineral ...
Breaking Biology Technology:Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 2Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 3Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 2Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 3ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 2ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 3
... Jan. 4 Anadys Pharmaceuticals,Inc. (Nasdaq: ANDS ) ... Annual,JPMorgan Healthcare Conference on Thursday, January 10, 2008 at ... held at the Westin St. Francis,Hotel in San Francisco., ... of Anadys,Pharmaceuticals, Inc., will present an update and overview ...
... 4 ARCA Discovery Inc., a privately held,biopharmaceutical ... other cardiovascular diseases, today announced Richard B.,Brewer, President ... 26th,Annual JPMorgan Healthcare Conference on Tuesday, January 8 ... Conference will be held January 7-10, 2008 at,the ...
... NEW YORK, Jan. 4 QED International ... a series of,20 underlying fund portfolios, today ... on Monday January 7, 2008, Alexion Pharmaceutical, ... Pharmaceutical, Inc. (Nasdaq: ASPV ) in,the ...
Cached Biology Technology:Anadys Pharmaceuticals to Present at the JPMorgan Healthcare Conference 2ARCA Discovery, Inc. to Present at 26th Annual JPMorgan Healthcare Conference on January 8, 2008 2QED International Associates Announces Changes to the HealthShares(TM) Autoimmune-Inflammation and Neuroscience Indexes - Correction 2
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Biology Products: