Navigation Links
Circadian gene helps the brain predict mealtime

By investigating how animals can predict the timing of food availability, researchers have identified the first gene critical for anticipation of mealtime. This gene, called Period 2, is a key component of the circadian time-keeping system. The findings are reported by Urs Albrecht of the University of Fribourg and Etienne Challet of the University Louis Pasteur/CNRS and colleagues in the October 24th issue of the journal Current Biology, published by Cell Press.

A daily scheduled meal is a potent time-giving cue that can reset the physiological timing of most organs, including the liver. In terms of animal behavior, a daily scheduled meal elicits anticipatory bouts of locomotor activity and changes in body temperature. These food-anticipatory behaviors are believed to be under the control of a food-entrainable mechanism--that is, a timing mechanism within the body that is set by food intake--but how this mechanism works at the molecular level is unknown.

In the new work, the researchers have found the first evidence that a single gene mutation can render mice totally unable to predict the time of food availability. Studying mice, they found that this lack of food anticipation at both behavioral and physiological levels is specifically associated with a mutation in the Period 2 gene, a gene that previous work had shown to play an important role in the brain's ability to run its central circadian clock according to daylight.

The researchers found that, interestingly, synchronization of timing between organs by scheduled meals is not affected by the Period 2 mutation, indicating that this gene is not crucial for scheduled food availability to affect the physiological coordination of tissues outside the central nervous system.

The authors of the study point out that the work they report provides a tool for investigating the brain's cerebral clockwork responsible for predicting mealtime--with this tool in hand, it will be possible
'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Jumping gene helps explain immune systems abilities
2. Protein helps regulate the genes of embryonic stem cells
3. Scientists reveal the shape of a protein that helps retroviruses break into cells
4. Thai spice helps cut blood sugar swings
5. Chemists synthesize molecule that helps body battle cancers, malaria
6. Ancient DNA helps clarify the origins of two extinct New World horse species
7. Massey Cancer Center researcher helps to identify a piece of the cancer puzzle
8. Study: Well-known protein helps stem cells become secretory cells
9. Beyond genes: Lipid helps cell wall protein fold into proper shape
10. Simple sea sponge helps scientists understand tissue rejection
11. New technique helps identify multiple DNA regulatory sites
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Circadian gene helps the brain predict mealtime

(Date:12/19/2014)... , Dec. 18, 2014   LaunchKey , the ... the post-password and Internet of Things era, today announced ... The venture round was led by Metamorphic Ventures with ... Venture Partners, VegasTechFund, and others.  LaunchKey has raised $4 ...
(Date:12/17/2014)... FORT BELVOIR, Va. , Dec. 15, 2014 ... make it easier to detect and prevent counterfeit microcircuits ... the agency started performing an in-house microcircuit anti-counterfeit initiative ... of purchased microcircuits while increasing their reliability throughout the ...
(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric data ... industry leaders such as Intel, Jabra, Atlas, and Scosche ... products. These products will be showcased at CES 2015, ... . "Our partners choose PerformTek ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... Moines, Iowa, USA January 15, 2008 The ... have announced that the Gishwati Forest Reserve is the ... into motion one of Africas most ambitious forest restoration ... as the location for Rwandas first national conservation park ...
... A specially developed carrot has been produced to help people ... Vegetable and Fruit Improvement Center studied the calcium intake of ... in calcium absorption. The research, which was done in collaboration ... the diet can help prevent such diseases as osteoporosis. ...
... Annals, published by SAGE, explores the problem of obesity in ... map for a healthier lifestyle both for them and for ... possible public policy options, the articles in the special issue ... such subjects as: ...
Cached Biology News:Rwanda's Gishwati Forest selected as site for historic conservation project 2Rwanda's Gishwati Forest selected as site for historic conservation project 3Got carrots? Vegetables may have bone to pick as calcium providers 2
(Date:1/22/2015)... January 22, 2015 Selexis SA, a ... Research Cell Banks (RCBs) used for drug discovery to ... Banks will include Next-Generation Sequencing (NGS) data ... de-risks biologic manufacturing by ensuring the integrity of the ...
(Date:1/22/2015)... 22, 2015   Cypher Genomics, Inc., the ... SQNM ), the leading molecular diagnostics ... generation noninvasive prenatal tests (NIPT). Through this agreement, ... Mantis™, to advance analysis of clinically-relevant fetal sub-chromosomal ...
(Date:1/22/2015)... 22, 2015  Derma Sciences, Inc. (Nasdaq: ... advanced wound care, announces that AMNIOEXCEL® and AMNIOMATRIX®, ... added to the Premier, Inc. Regenerative Skin Grafting ... the AMNIOEXCEL® and AMNIOMATRIX® product lines, which continue ...
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 PlasmaTech ... care in critical areas, announced the closing of an underwritten ... to purchase up to an aggregate 3,500,000 shares of common ... $.01 per warrant.  The warrants have a per share exercise ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3
... and business ... development activities, MEDFORD, ... of the unique microfluidic microarray system Geniom,today announced the formation ... the forefront of genetics and genomics,research. The SAB members, from ...
... March 31 /Xinhua-PRNewswire-FirstCall/ -- Huifeng Bio-,Pharmaceutical Technology, Inc. (OTC Bulletin ... raw materials for use in,pharmaceutical, nutraceutical and food production, is ... December 31, 2007., Full Year 2007 Highlights:, The ... full year,ended Dec. 31, 2007., ...
... N.Y., March 31 Profect(TM) Medical,Technologies, a ... software,and clinical photography systems, today announced the ... the hiring of Holly Smith as its,Director., ... clients with an,array of customized photographic and ...
Cached Biology Technology:febit Forms Scientific Advisory Board 2febit Forms Scientific Advisory Board 3Huifeng Bio-Pharmaceutical (HFGB) Announces 2007 Full Year Results 2Huifeng Bio-Pharmaceutical (HFGB) Announces 2007 Full Year Results 3Holly Smith Joins Profect as Director of Clinical Imaging Services 2
Request Info...
Request Info...
... Biosearch Technologies has been at the ... accelerate the discovery and application of ... FRET probes and primers or 100 ... applications, Biosearch can meet your most ...
... Cultrex High Protein Concentration Basement ... for use in in vivo applications ... gelling times, increased gel strength, and ... HC20+ has the advantage of lot-to-lot ...
Biology Products: