Navigation Links
Cincinnati surgeons report new treatment for often-fatal injury

University of Cincinnati (UC) surgeons have developed a new, minimally invasive method for repairing a common and deadly form of aortic injury--an advance that could help reduce the number of deaths caused by auto accidents and major falls.

The potentially life-saving technique is reported by Joseph Giglia, MD, interim director of UC's division of vascular surgery, and his team in the March edition of Annals of Vascular Surgery.

Dr. Giglia estimates that 80 to 90 percent of the patients who suffer this injury--known as blunt thoracic aortic trauma--die before ever reaching a hospital.

The aorta is the main artery that carries oxygenated blood from the heart to be distributed throughout the body.

A severe blunt thoracic accident, usually a non-penetrating "deceleration" injury, can jerk the aorta forward and back again, causing it to crack.

If all three layers of the aorta rupture immediately, the patient will die almost instantly from blood loss. If the outer layer remains intact, however, a weakened area called a pseudoaneurysm can form, which often bursts later.

Surgeons must repair the damaged aorta quickly before it does rupture, killing the patient.

The Food and Drug Administration has yet to approve a device for treatment of this type of injury, says Dr. Giglia, and custom-made devices are usually large and difficult to use in an emergency setting.

Dr. Giglia's team found that by placing a standard surgical stent--a tube-shaped metallic support structure--in the aorta and lining it with a series of small synthetic grafts (endografts) they could effectively protect the damaged area without stopping blood flow to the rest of the body.

The endografts are regularly used in vascular surgery to treat aneurysms in the abdomen, Dr. Giglia explains, but they are too short to fully bridge the damaged area in the chest.

"Used alone, extender cuffs are hard to align and often slip into th e defect to cause further complications," says Dr. Giglia. "Using a fixed stent provides an easy-to-see 'scaffolding' that can guide the surgeon to more accurately secure the extender cuffs and create a strong seal."

Once in place, the dual lining supports the weakened vessel walls and allows blood to continue flowing through the aorta without applying pressure to damaged area.

"Our method gives emergency surgeons a reliable way to repair difficult injuries with readily accessible materials," Dr. Giglia says. "More people can be treated--and potentially saved--with these minimally invasive techniques."

Standard "open" treatment for this type of injury can work, says Dr. Giglia, but it puts significant stress on the patient's heart and brain and increases the risk for heart attack, bleeding, paraplegia and other problems.

J. Keith Thompson, DO, and Amy Reed, MD, both of UC, were coauthors on this study.


'"/>

Source:University of Cincinnati


Related biology news :

1. Plastic surgeons countdown first full facial transplantation
2. Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find
3. No-scalpel vasectomies by skilled surgeons may speed recovery
4. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
5. Surprising findings reported about iron overload
6. Researchers report new pro-inflammatory role for anti-inflammatory enzyme
7. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
8. Leprosy genome tells story of human migrations, French researchers report in Science
9. Novel live reporting system to track cells
10. Biased reporting found in cancer prognostic studies
11. New lead reported in tumor angiogenesis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/2/2016)... 2016   Parabon NanoLabs (Parabon) announced ... Research Office and the Defense Forensics and Biometrics ... the company,s Snapshot Kinship Inference software ... generally, defense-related DNA forensics.  Although Snapshot is best ... and ancestry from DNA evidence), it also has ...
(Date:1/28/2016)... SYNA ), a leading developer of human interface solutions, today ... --> --> Net revenue ... to the comparable quarter last year to $470.5 million. Net income ... $0.93 per diluted share. --> ... 2016 grew 9 percent over the prior year period to $60.3 ...
(Date:1/22/2016)... 22, 2016 ... the "Global Biometrics Market in Retail ... --> http://www.researchandmarkets.com/research/p74whf/global_biometrics ) has ... Biometrics Market in Retail Sector 2016-2020" ... Research and Markets ( http://www.researchandmarkets.com/research/p74whf/global_biometrics ) ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... - New FDA action date of July ... action date of July 22, 2016   --> ... 22, 2016   - Lifitegrast has the ... for the treatment of signs and symptoms of dry eye disease ... to be the only product approved in the U.S. in the past decade indicated for ...
(Date:2/4/2016)... ... February 04, 2016 , ... Shimadzu ... quad LC-MS, host live demos and poster sessions, and present on the analysis ... conference takes place March 6 to 10 at the Georgia World Congress Center ...
(Date:2/4/2016)... , Feb. 4, 2016 Beike Biotechnology, ... various medical institutions attended a ceremony in late 2015 ... personalized cell therapy in 2016. --> ... Clinical Translation Platform for Personalized Cell Therapy" was hosted ... Cell Production Center, both subsidiaries of Beike Biotechnology Co., ...
(Date:2/4/2016)... VANCOUVER, British Columbia and MENLO PARK, ... Inc. (OTCQX: DMPI) ("DelMar" and the "Company"), a biopharmaceutical ... therapies, today announced that it will present at the ... on Monday, February 8, 2016 at 10:00 a.m. EST in ... Jeffrey Bacha , DelMar,s president and CEO, will provide an ...
Breaking Biology Technology: