Navigation Links
Cigarette smoking impedes tendon-to-bone healing

ine in St. Louis. "Those early weeks are a time when there's a lot of tissue healing and remodeling occurring, and we're trying to learn whether there may be increased vulnerability to early failure in smokers."

This study, the first to evaluate the effects of nicotine on rotator cuff repair, found that when rats were exposed to nicotine following rotator cuff repair, inflammation persisted for a longer time in the shoulder joint. That's detrimental to healing. The researchers also noted that there was less cellular proliferation in the rats' surgically repaired shoulders and decreased collagen production, leading to inferior healing.

"When you have an injury and a repair, new cells come in and start to facilitate healing," Galatz says. "When the new cells arrive, they make proteins such as collagen to form the junction between tendon and bone. And in the rats exposed to nicotine, we saw lower cellular proliferation."

The rats also made less type-I collagen and had different biomechanical properties in their shoulders following rotator cuff repair. Measuring properties called maximum stress and maximum force, the researchers found that shoulder joints in the nicotine-exposed rats were weaker.

"Those changes were most apparent at earlier time points, and shoulder strength tended to equalize between the two groups about 8 weeks after surgery," Galatz says. "But certainly, the tissue was weaker early on and more vulnerable to re-injury."

Galatz and colleagues studied healing in the shoulders of 72 rats following rotator cuff surgery. The researchers implanted tiny, osmotic pumps under the skin of the rats, and those pumps delivered either nicotine or an inactive saline solution. Saline pumps were implanted to ensure that any changes observed between groups of rats resulted from nicotine exposure rather than from having a pump implanted beneath the skin. In the rats that got nicotine, the pumps maintained nicotine levels
'"/>

Source:Washington University School of Medicine


Page: 1 2 3

Related biology news :

1. Cigarette smoke blocks cell repair mechanism, University of Florida study shows
2. Research shows smoking adds a decade to reproductive age of IVF patients
3. OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
4. Indias smoking gun: Dino-killing eruptions
5. Alcoholism, smoking and genetics among Plains American Indians
6. Both alcoholism and chronic smoking can damage the brains prefrontal cortex
7. Researchers test new way to quit smoking
8. Blood test predicts success of quitting smoking using the nicotine patch
9. Quitting smoking improves lung function considerably
10. High HPV concentrations combined with smoking significantly raise risks of cervical cancer
11. Heavy smoking cuts womens chance of pregnancy -- even with donated oocytes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cigarette smoking impedes tendon bone healing

(Date:8/20/2014)... are athletes who have suffered concussions ready to return ... found that high school athletes who head back on ... a significant regression in their abilities to simultaneously walk ... seen in changes in their balance and/or altered walking ... of the 12 had returned to activity in less ...
(Date:8/20/2014)... Tech,s Wu Feng has built upon a National Science ... the Cloud" program, and synergistically complemented it with subsequent ... Air Force on "big computing" for mini-drones and a ... of Health on "big data" for the life sciences. ... from each grant, he was able to tell a ...
(Date:8/20/2014)... developed by researchers at the University of Missouri School ... a life-threatening heart condition caused by muscular dystrophy. ... Lai, Ph.D., the leading author of the study and ... Department of Molecular Microbiology and Immunology. "This is just ... to a treatment for people with this devastating heart ...
Breaking Biology News(10 mins):Recovery reversal seen in Oregon study of returning concussed athletes 2Recovery reversal seen in Oregon study of returning concussed athletes 3The internet was delivered to the masses; parallel computing is not far behind 2The internet was delivered to the masses; parallel computing is not far behind 3The internet was delivered to the masses; parallel computing is not far behind 4Gene therapy protects mice from lethal heart condition, MU researchers find 2
... good health. Like plants that thrive in the sun, we ... production of vitamin D. In the past few decades, however, ... fear of the potential dangers of UV radiation and the ... environments centered on virtual reality, we are all spending much ...
... World Water Day on Sunday, 22 March aims to ... drinking water on our planet. In a densely populated ... ever before. Helmholtz scientists in the research field ... these problems. In cooperation with partners from other countries ...
... Writings at Stevens Institute of Technology will host "Ravens at ... by Bernd Heinrich, on Wednesday, April 1, 2009. The event ... 4 p.m. to 5:30 p.m. The journalist Bill McKibben ... he,s a great writer, period." A professor emeritus of biology ...
Cached Biology News:The sunlight solution for better health 2The sunlight solution for better health 3Research to secure a safe water supply 2Research to secure a safe water supply 3Research to secure a safe water supply 4
(Date:8/19/2014)... IRVINE, Calif. (PRWEB) August 19, 2014 ... Indiegogo campaign to raise $200,000 to fund a ... diagnostic device. , This development is a ... one-size-fits-all model of care to the implementation of ... patient-centric method of practicing medicine. , Indiegogo contributions ...
(Date:8/19/2014)... Aug. 19, 2014 CSSi, the leader in ... announced the formation of the company,s Medical and Clinical ... addition of Dr. William E. Gannon, Jr. ... The MCAB, with Dr. Gannon,s ... therapeutic areas and set strategic goals for the advancement ...
(Date:8/18/2014)... Dallas, Texas (PRWEB) August 19, 2014 ... China Linalool Industryā€¯ is a professional and in-depth ... report provides basic Linalool information, including its ... well as industry overview. This research covers the ... well as global industry analysis covering macroeconomic environment ...
(Date:8/18/2014)... NYElectronic devices with unprecedented efficiency and data ... that use built-in electric polarizations to read ... inside most popular data-driven technology. But ferroelectrics ... blocks, including a curious habit of "forgetting" ... the U.S. Department of Energy,s Brookhaven National ...
Breaking Biology Technology:Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 2CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 3Linalool Industry & Diphenylamine Market (Global, China) 2014 Analysis Now Available at DeepResearchReports.com 2Linalool Industry & Diphenylamine Market (Global, China) 2014 Analysis Now Available at DeepResearchReports.com 3Linalool Industry & Diphenylamine Market (Global, China) 2014 Analysis Now Available at DeepResearchReports.com 4Promising ferroelectric materials suffer from unexpected electric polarizations 2Promising ferroelectric materials suffer from unexpected electric polarizations 3Promising ferroelectric materials suffer from unexpected electric polarizations 4
... Management Form Company ... Podiatry Markets, FAIRFIELD, N.J., May 13 Medimetriks ... led by the founder and the key Senior Management ... will develop, license and,commercialize innovative prescription products for the ...
... 13 /PRNewswire-FirstCall/ - AEterna Zentaris Inc.,(NASDAQ: ... company focused on,endocrine therapy and oncology, today ... 2 study of subcutaneously,administered LHRH antagonist cetrorelix ... has been accepted for publication in an,upcoming ...
... SAN DIEGO and TUCSON, Ariz., May 12 ,University-affiliated ... creating opportunities for sustainable development and,innovation within economies ... in La Jolla on June 16 to share ... maximizing the effectiveness of parks,specializing in biotechnology development., ...
Cached Biology Technology:Medimetriks Pharmaceuticals, Inc. Begins Operations 2AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal 2AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal 3AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal 4AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal 5AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal 6University Research and Science Parks Create Sustainable Innovation 2
RABBIT ANTI QUINOLINIC ACID...
RAT ANTI MOUSE METALLOPHILIC MACROPHAGES...
... All MagCellect Ferrofluid products perform ... with R&D Systems MagCellect Magnet. ... this neodymium iron boron permanent ... x 75 mm test tubes ...
Request Info...
Biology Products: