Navigation Links
Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot

Mayo Clinic researchers have found that the cause of chronic sinus infections lies in the nasal mucus -- the snot -- not in the nasal and sinus tissue targeted by standard treatment. The findings will be published in the August issue of Journal of Allergy and Clinical Immunology and are available online.

"This strikingly teaches against what has been thought worldwide about the origin of chronic sinus infection: that inflammatory cells break down, releasing toxic proteins into the diseased airway tissue," says lead researcher and Mayo Clinic ear, nose and throat specialist Jens Ponikau, M.D. "Instead we found that these toxic proteins are released into the mucus, and not in the tissue. Therefore, scientists might need to take not only the tissue but also the mucus into account when trying to understand what causes chronic sinus infections and probably other airway diseases."

The findings could significantly change the way chronic sinus infection is treated, according to Dr. Ponikau.

"This has far-reaching implications," says Dr. Ponikau. "This suggests a beneficial effect in treatments that target primarily the underlying and presumably damage-inflicting nasal and sinus membrane inflammation, instead of the secondary bacterial infection that has been the primary target of treatments for the disease. Also, some surgeons have already started to change the way they do surgery for patients with chronic sinus infections, focusing now on removing the mucus, which is loaded with toxins from the inflammatory cells, rather than the tissue during surgery. Leaving the mucus behind might predispose patients for early recurrence of the chronic sinus infection."

Dr. Ponikau conducted this research along with Hirohito Kita, M.D., and Gail Kephart, Mayo Clinic allergic diseases researchers. David Sherris, M.D., and Eugene Kern, M.D., both former Mayo Clinic ear, nose and throat specialists who now
'"/>

Source:Mayo Clinic


Page: 1 2

Related biology news :

1. FDA Clears the Way for Generic Versions of Transdermal Patches to Treat Chronic Pain
2. FDA Approves New Treatment for Chronic Hepatitis B
3. Chronic jet-lag conditions hasten death in aged mice
4. Chronic pain up almost 40 percent among US workers in past decade
5. Chronic fatigue syndrome impairs a persons slow wave activity during sleep
6. HIV Infection Still On The Rise
7. Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
8. Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure
9. Infection alarm yields clues to immune system behavior
10. Infections could contribute to adult brain tumours
11. Infection detectives use disease fingerprints to track common infections in children
Post Your Comments:
(Date:9/18/2014)... Washington State University researchers have developed a unique method ... waste cleanup in rural areas. , The first ... inexpensive and quick way to clean up waste from ... reducing pollution. , Professor Haluk Beyenal and graduate ... and Architecture discuss the system in the online edition ...
(Date:9/18/2014)... USA A new GSA Bulletin study ... lower Rio Puerco and Chaco Wash in northern New ... from salt cedar and willow, investigators were able to ... greater. They then combined this data with aerial imagery, ... history of these arroyos. , Arroyos are deep, oversized ...
(Date:9/18/2014)... A sleep-promoting circuit located deep in the primitive brainstem ... by researchers at Harvard School of Medicine and the ... this is only the second "sleep node" identified in ... necessary and sufficient to produce deep sleep. , Published ... study demonstrates that fully half of all of the ...
Breaking Biology News(10 mins):Researchers develop unique waste cleanup for rural areas 2Tree rings and arroyos 2Tree rings and arroyos 3Tree rings and arroyos 4Tree rings and arroyos 5Tree rings and arroyos 6Tree rings and arroyos 7No sedative necessary: Scientists discover new 'sleep node' in the brain 2
... , Hormones shape our bodies, make us fertile, excite our ... they govern the behaviors that separate men from women. But ... of California, San Francisco (UCSF) has uncovered many genes influenced ... that, in turn, govern several specific types of male and ...
... 2012 The Institute for Aging Research of Hebrew SeniorLife, ... Lisa Samelson and the Institute were awarded a $2.7 million ... five-year study to better understand the cause of hyperkyphosis, a ... , "Despite the severe impact hyperkyphosis can have on ...
... cellular and molecular biology, at the University of Tennessee, ... head. The biochemist and a team of researchers have ... produce efficient and inexpensive energy. Bruce collaborated with ... Polytechnique Federale in Switzerland to develop a process that ...
Cached Biology News:Male and female behavior deconstructed 2Male and female behavior deconstructed 3Male and female behavior deconstructed 4Institute for Aging research awarded $2.7 million grant to investigate 'dowager's hump' 2UT biosolar breakthrough promises cheap, easy green electricity 2UT biosolar breakthrough promises cheap, easy green electricity 3
(Date:9/18/2014)... Austin, TX (PRWEB) September 18, 2014 ... of integrated urological and interventional radiology products and ... (also known as cryotherapy and cryoablation) versus external ... Mid-Atlantic Section of the American Urological Association (MAAUA) ... , "Comparing Relative Effectiveness of Cryosurgery and ...
(Date:9/18/2014)... 18, 2014 About POCT ... outside a clinical laboratory. It helps in making ... treatments and medication. POCT is gaining popularity due ... diseases such as diabetes, heart disease, and obesity. ... are standardized to minimize errors during the diagnosis ...
(Date:9/18/2014)... DALLAS , Sept. 18, 2014 /PRNewswire-iReach/ -- ... and China Acetic Acid Industry" and "2014 Deep ... Industry" reports to its research database. ... 2014 Deep Research Report on Global and China ... research report on China ...
(Date:9/18/2014)... A novel robotic system that can operate ... being tested as part of a biomedical research partnership ... the aim of determining if the robot, in conjunction ... faster, more accurate, less costly, and less discomforting for ... to deliver prostate cancer therapies with greater precision. , ...
Breaking Biology Technology:HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2POCT Market in China 2014-2018 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6
... Solutions, LLC, Santa Clara, CA, a manufacturer of measurement ... the technical demonstration of TruFluor(TM) pH, a single use ... on March 17, 2009.The TruFluor pH and temperature sensor ... an optical reader, and a transmitter. The single-use sheath ...
... is available in German . , ... one water-repellant (hydrophobic) end, spontaneously aggregate in aqueous solutions ... is responsible for the effects of detergents and soaps. ... makes it water-soluble. Cell membranes are also based on ...
... CLARA, Calif., March 6 Finesse Solutions, LLC, ... control solutions for bioprocess applications, and Nova Biomedical, ... monitoring announced the release of a TruBio(TM) plug-in ... Nova FLEX(R) analyzers. OPC is the de facto ...
Cached Biology Technology:Finesse Demonstrates TruFluor(TM) pH, a Single-Use Optical pH Sensor and Transmitter 2Bristly spheres as capsules 2UPDATE: OPC Connectivity Between TruBio Software and Nova FLEX Analyzers 2
... easy to supply microplates, deepwells, and tips ... convenience in mind, iLink incorporates multiple functions ... The iLink software is the key to ... that can be copied and installed as ...
... continue to grow, the need for greater ... become necessary, especially when discerning very similar ... C1si Confocal Microscope System gives you a ... not available in conventional confocal systems, with ...
... Life Science LAS-3000 imaging system combines ... simplified user interface, providing significantly improved ... of modularities. The LAS-3000 provides significantly ... range of applications including: fluorescence, chemifluorescence, ...
The LAS-3000 imaging system combines new CCD camera technology with a simplified user interface to provide significantly improved system sensitivity with a wide range of modularities. This system is...
Biology Products: