Navigation Links
Chimp genome reveals a retroviral invasion

It's been known for a long time that only 2% -- 3% of human DNA codes for proteins. Much of the rest of our genomes -- often referred to as junk DNA -- consists of retroelements: genomic elements that are transcribed into RNA, reverse-transcribed into DNA, and then reinserted into a new spot in the genome. Human endogenous retroviruses make up one class of these retroelements. Retroviruses can insinuate themselves into the host's DNA in either soma (nonreproductive cells) or the germline (sperm or egg).

If the virus invades a nonreproductive cell, infection may spread, but viral DNA will die with the host. A retrovirus is called endogenous when it invades the germline and gets passed on to offspring. Because endogenous retroviruses can alter gene function and genome structure, they can influence the evolution of their host species. Over 8% of our genome is made of these infectious remnants -- infections that scientists believe occurred before Old World and New World monkeys diverged (25 -- 35 million years ago).

In a new study, Evan Eichler and colleagues scanned finished chimpanzee genome sequence for endogenous retroviral elements, and found one (called PTERV1) that does not occur in humans. Searching the genomes of a subset of apes and monkeys revealed that the retrovirus had integrated into the germline of African great apes and Old World monkeys -- but did not infect humans and Asian apes (orangutan, siamang, and gibbon). This undermines the notion that an ancient infection invaded an ancestral primate lineage, since great apes (including humans) share a common ancestor with Old World monkeys.

Eichler and colleagues found over 100 copies of PTERV1 in each African ape (chimp and gorilla) and Old World monkey (baboon and macaque) species. The authors compared the sites of viral integration in each of these primates and found that few if any of these insertion sites were shared among the primates. It appears therefore that the sequences have
'"/>

Source:PLoS


Page: 1 2 3

Related biology news :

1. Chimpanzees can transmit cultural behavior to multiple generations
2. Chimpanzee study reveals genome variation hotspots
3. Chimpanzees found to use tools to hunt mammalian prey
4. Man and mouse share genome structures
5. Whole genome fine map of rice completed
6. Study finds more than one-third of human genome regulated by RNA
7. A bacterial genome reveals new targets to combat infectious disease
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Highly adaptable genome in gut bacterium key to intestinal health
10. Fleshing out the genome
11. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chimp genome reveals retroviral invasion

(Date:11/18/2014)... , Nov. 18, 2014  The Secure Identity ... Association today jointly announce the formation of The ... of its Identity and Biometric Entry and ... Framework received official support from BORDERPOL, the international ... improve and provide expertise regarding border security, traveler ...
(Date:11/18/2014)... BETHESDA, Md. , Nov. 17, 2014 The ... European and U.S. regulatory agencies will speak and at least ... Quality Metrics Conference at the Omni Shoreham Hotel in ... is pleased once again to have significant support from the ... and Europe in our effort to ...
(Date:11/15/2014)... , Nov. 13, 2014  While we may still be ... McCoy used in "Star Trek" to gain instant access to ... to work with smartphones and tablets for monitoring and measuring ... healthcare world. This may seem a tad Orwellian to some, ... adopt some of these technological opportunities into their healthcare regime. ...
Breaking Biology News(10 mins):Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4
... available in French . , Dopamine replacement ... with Parkinson,s disease, can, at times, adversely affect cognition. ... Head of the Neurophysiological and Neuroimaging Research theme at ... de Montral (IUGM), which is affiliated with the Universit ...
... , Birds with high levels of stress hormones have ... to their brood, according to new biology research at ... stress hormone is often thought to indicate an individual ... mating success. However, our research indicates that tree swallows ...
... and new research by University of California, Berkeley, neuroscientists ... and other highly emotional experiences lead to incredibly strong ... 14) in advance of publication in the journal ... report a new way for emotions to affect memory: ...
Cached Biology News:Researchers identify why dopamine replacement therapy has a paradoxical effect on cognition 2Stress may lead to better bird parenting 2Fear boosts activation of young, immature brain cells 2Fear boosts activation of young, immature brain cells 3
(Date:12/19/2014)... Arlington, MA (PRWEB) December 18, 2014 ... products for ophthalmology and wound care. The National Eye ... has awarded LayerBio a Phase I SBIR grant to ... , Cataracts are the most common cause of vision ... cause of blindness worldwide. According to Dr. Ken Mandell, ...
(Date:12/19/2014)... 18, 2014 iLab Solutions, the global ... of Siri Bryant as the new Director of Institutional ... Core Implementations. These two new leadership positions were created ... by ensuring that iLab continues to meet the needs ... four years, iLab has been deployed at over 450 ...
(Date:12/19/2014)... With only 2 weeks left of 2014, ... Biohit products . The product specials include Buy 1 ... Trade-in Program, and free pipette tips. , Sartorius mLINE ... world. They are ideal for lab technicians performing long ... ,     Full volume range of 0.1 uL to 10 ...
(Date:12/19/2014)... DALLAS , Dec. 18, 2014   ISN ... Health & Safety Performance Indicators publication series. ... hours of activity reported in 2013 within its online ... health and safety key performance indicator (KPI) statistics. ... Hiring Clients, U.S. publication is available in ...
Breaking Biology Technology:LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... CARLSBAD, Calif., Jan. 6 AutoGenomics, a leader in ... company has been invited and has accepted to present ... January 12-15, 2009 at the Westin St. Francis Hotel ... President & CEO will provide an overview of the ...
... Jan. 6 /PRNewswire-FirstCall/ - SemBioSys Genetics Inc. (TSX:SBS), ... plants, today announced it has received US$2,500,000 from ... for the option agreement and issuance of 2,400,000 ... 2008. The transaction provides MannKind with the option ...
... ST. LOUIS, Mo., Jan. 6 Sigma-Aldrich,(Nasdaq: ... with the acquisition of,Seppro(R) affinity depletion technology and ... Inc. Seppro depletion products enable,scientists to measure ... range of mammalian and plant biological samples. ...
Cached Biology Technology:SemBioSys receives US$2.5 million from option agreement with MannKind for plant-produced insulin 2SemBioSys receives US$2.5 million from option agreement with MannKind for plant-produced insulin 3Sigma-Aldrich Acquires Seppro(R) Depletion Technology From GenWay Biotech 2Sigma-Aldrich Acquires Seppro(R) Depletion Technology From GenWay Biotech 3