Navigation Links
Chemo combination improves survival in asbestos-related cancer

People with mesothelioma ?a form of cancer associated with asbestos exposure ?have a higher survival rate when treated with a combination of two cancer drugs, a large multicenter study finds.

Mesothelioma, a rare but aggressive form of cancer that occurs in the lining of the lungs, heart and abdomen, is associated with exposure to asbestos. There is no known cure.

In the study, patients receiving pemetrexed and cisplatin ?along with the vitamin supplements folic acid and B12 ?survived nearly three months longer than patients getting cisplatin alone.

Researchers led by John Green, M.D., at the Clatterbridge Center for Oncology in England, reviewed a study of 448 patients with advanced mesothelioma who were treated with either the single drug or the combination.

"Pemetrexed used in combination with cisplatin significantly increases the length of survival, when compared with cisplatin alone," the researchers say. "Further research is needed into the optimum treatment regimen for pleural mesothelioma."

The review appears in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

The researchers examined data from a clinical trial of 20 treatment centers in Europe, the Americas, Australia and Asia. Eighty-one percent of the patients were men, with an average age of 61. Patients who received the combination treatment survived an average 2.8 months longer.

Patients receiving both medications also reported improved quality of life in terms of fatigue, loss of appetite, pain and cough.

During the early stages of the trial, patients receiving pemetrexed had serious symptoms of toxicity, including drug-related death. Other side effects included blo
'"/>

Source:Center for the Advancement of Health


Page: 1 2 3

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
3. Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer
4. Chemotherapy gel may fight breast cancer and reduce breast deformity
5. Chemotherapy temporarily affects the structures of the human brain
6. DNA Recombination and Repair—A New Twist to RecA Function
7. Wake Forest scientists find new combination vaccine effective against plague
8. Study shows combination of immune substances to be safe
9. Novel therapy combinations gain ground in treating hepatitis
10. Recombination protein dynamics observed with single monomer resolution
11. New study suggests promising drug combinations for sleeping sickness
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chemo combination improves survival asbestos related cancer

(Date:6/19/2013)... 19, 2013 Elsevier, a world-leading provider of scientific, ... to announce the launch of a new open access ... of GeoResJ , Elsevier,s earth and planetary science ... The journal aims to provide a forum for rapid ... field. The journal will be co-edited by six Executive ...
(Date:6/18/2013)... awarded a $394,300 grant from the Tarrant Regional ... in the new facilities of the 150-mile Integrated ... professor of civil engineering, will investigate the best ... water in an effort to eliminate biological growths ... monochloramine is widely practiced throughout the United States. ...
(Date:6/18/2013)... National Institutes of Health has awarded $12.7 million ... selection of pharmaceutical industry compounds to explore new ... Alzheimer,s disease, Duchenne muscular dystrophy and schizophrenia. The ... for Existing Molecules, is led by the National ... by the NIH Common Fund. , The process ...
Breaking Biology News(10 mins):UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2NIH to fund collaborations with industry to identify new uses for existing compounds 2NIH to fund collaborations with industry to identify new uses for existing compounds 3NIH to fund collaborations with industry to identify new uses for existing compounds 4
... and their colleagues at other research centers have found a ... the impact of the aging process. Their study, which will ... lends more credence to the free-radical theory of aging. , ... can be damaging to the body at the cellular level. ...
... Results showed that the microbes in about a half a ... the rumen, the largest chamber of a cow's stomach - ... voltage needed to run one rechargeable AA-sized battery, said Ann ... agricultural and biological engineering at Ohio State University. , While ...
... brain develops, neurons reach out helter-skelter forming new connections, ... the brain chooses which connections to keep and which ... branches have the most electrical activity—a finding that could ... , The work, published in the April 21 issue ...
Cached Biology News:Researchers extend mouse lifespan by protecting against free radicals 2Researchers extend mouse lifespan by protecting against free radicals 3It's electric: Cows show promise as powerplants 2It's electric: Cows show promise as powerplants 3Speak up: Louder neurons form more connections 2
(Date:6/19/2013)... , June 19, 2013 Synthetic Biologics, Inc. ... prevention and treatment of serious infectious diseases, announced today that ... th Annual OneMedForum New York Conference on Thursday, June ... York City . Mr. Riley is scheduled to present ... of Synthetic Biologics, presentation can be accessed by logging onto ...
(Date:6/19/2013)...   NineSigma , Inc., of Cleveland ... launch, NineSights.com is now the innovation engine ... worldwide community of innovators. From technology developers, ... NineSights stands out for its large community of innovators ... disciplines, all vetted by NineSigma. The community is free ...
(Date:6/19/2013)... ANGELES , June 19, 2013 Biotechnology industry ... teaming up with financial software provider BlackLine Systems ... SAP ) for a webinar next week entitled ... Uses Solutions from BlackLine and SAP to Help Keep Its ... (Logo: http://photos.prnewswire.com/prnh/20061117/LAF027LOGO ) The webinar, geared ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 India’s ... business can potentially be worth up to a ... opportunity, the Indian government is taking serious action ... the process. , This presentation will examine:, ... regulations ,     Immediate and long term impacts ...
Breaking Biology Technology:Synthetic Biologics to Present at OneMedForum New York 2013 2NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 2NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 3Amgen Joins BlackLine Systems, SAP for Webinar on Automating Account Reconciliations 2Amgen Joins BlackLine Systems, SAP for Webinar on Automating Account Reconciliations 3Amgen Joins BlackLine Systems, SAP for Webinar on Automating Account Reconciliations 4
... companies tied for the top prize at the first-annual ... close of the Entrepreneurs Conference Wednesday evening in Milwaukee, ... first and second place, or $55,000. , ,Other category ... IntelliMentor. , ,The quality of the business plans was ...
... MILWAUKEE The Wisconsin Entrepreneurs Conference ... flourish in a competitive market, with a seminar ... market potential of ideas. Entrepreneurs and industry representatives ... shared strategies for making a product survive and ...
... MADISON Be honest: Everything you know about nanotechnology is ... meets the super-model, and within the space of about 30 ... nerdy baby wearing eyeglasses. , ,Dont feel left out, however, ... backyard grill. The field of nanotechnology is so new that ...
Cached Biology Technology:Governors business-plan contest has a surprise ending 2Governors business-plan contest has a surprise ending 3Governors business-plan contest has a surprise ending 4Governors business-plan contest has a surprise ending 5Governors business-plan contest has a surprise ending 6Entrepreneurs learn to assess potential ideas 2Entrepreneurs learn to assess potential ideas 3Small wonders: Intersection of biotech and nanotech will produce big advances 2Small wonders: Intersection of biotech and nanotech will produce big advances 3
... 23 years of experience in the development ... antibodies to large and small peptides, proteins, ... plasmid DNA-encoded antigens. We understand and appreciate ... hybridoma development programs are never "cookbook". We ...
... Solubility Service, We deliversoluble protein or ... technology yields the best soluble protein results ... each clone submitted , Powerful results on ... protein Solubility Optimization Service (SOS) uses proprietary ...
... The Rapid-Screen cDNA Library Panels were ... just three sets of PCRs to identify ... analysis is performed in a 96-well "Master ... from 5,000 clones. Having identified the positive ...
... Formula variant: With the macro- ... Murashige and Skoog (1962) and ... Gamborg, et al. (1968). Preparation ... 4.4 grams of powder per ...
Biology Products: