Navigation Links
Chemicals in brown algae may protect against skin cancer

ntrols: Two were fed the standard diet with and without UV exposure, and two had the BAP solvent applied to the skin with and without UV exposure.

The mice received the BAPs for two weeks before UVB exposure began, followed by 24 weeks of increasing UVB exposure according to a standardized schedule.

The researchers then counted the number of tumors in the treatment and control groups and calculated their size.

Animals exposed only to UVB developed an average of 8.5 skin tumors. The animals fed the lower and the higher dose of BAPs developed an average of 4.7 and 3.7 tumors respectively. Of those given the topical treatment, the lower and higher doses developed 3.4 and 4.6 tumors respectively.

In terms of tumor volume, the animals fed BAPs at the lower and higher doses had tumors that were 34 percent and 40 percent smaller than those in animals exposed to UVB alone. Of those given the topical treatment, the lower and higher dose animals had tumors that were 27 percent to 43 percent smaller than animals exposed to UVB alone.

In addition, the researchers compared the groups for skin levels of the enzyme cyclooxygenase-2 (COX-2) and of the hormone-like substance prostaglandin E2, both of which are strong indicators of inflammation, and for cell proliferation rates.

Animals treated with BAPs showed lower levels of both COX-2 and prostaglandin E2.

The researchers found that the dietary BAPs reduced COX-2 activity by 74-82 percent, and that the topical BAPs reduced it by 66-82 percent. They also measured lower rates of cell proliferation in BAP-treated animals.

"Both the oral and topical BAP treatment reduced COX-2 and prostaglandin E2 cell proliferation levels in the skin," Stoner says, "which corresponds with fewer tumors and small tumors in the treated animals."


'"/>

Source:Ohio State University


Page: 1 2

Related biology news :

1. Chemicals in tattoo inks need closer scrutiny
2. How nice, brown rice: Study shows rice bran lowers blood pressure in rats
3. Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
4. Deep sea algae connect ancient climate, carbon dioxide and vegetation
5. The secret life of algae
6. Cellular antennae on algae give clues to how human cells receive signals
7. A new male-specific gene in algae unveils an origin of male and female
8. Detecting microalgae in coastal waters
9. Florida Tech explores microalgae for biofuel
10. Common algae helps illustrate mammalian brain electrical circuitry
11. Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chemicals brown algae may protect against skin cancer

(Date:9/29/2014)... article published online in Behavioral Brain Research ... brain as a result of chronic alcohol exposure that ... , Clinical assessments and research indicate that individuals with ... This can occur when people are actively drinking, when ... abstaining. , "Sleep-wake disturbances can last for months, ...
(Date:9/29/2014)... when the supercontinent of Pangea was starting to break up ... kinds of reptiles called phytosaurs and rauisuchids were at the ... the two top predators didn,t interact much as the former ... land. But those ideas are changing, thanks largely to the ... online in September in the German journal Naturwissenschaften ...
(Date:9/29/2014)... Growing Demand From Huge ... Security Concerns Continue to Propel Biometrics Market in ... is one of the fastest growing biometrics markets ... majorly in various government projects such as National ... biometrics dominates the country,s biometrics market, with other ...
Breaking Biology News(10 mins):Tooth buried in bone shows prehistoric predators tangled across land, sea 2India Biometrics Market to Surpass USD2.7 Billion by 2019, Finds TechSci Research Study 2India Biometrics Market to Surpass USD2.7 Billion by 2019, Finds TechSci Research Study 3
... flat. Even the flattest of basement membranes has topography; ... , Unlike the princess kept awake by the ... cultured on a substrate deliberately printed with nanoscale ... of Wisconsin–Madison. , The researchers used soft ...
... been stopped early due to preliminary results indicating that ... HIV during heterosexual intercourse by 53 percent. , The ... 12 to review the interim data. Based on the ... trial and recommended that all men enrolled in the ...
... Give or take a few dozen trillions, a human adult ... roundworm has exactly 959 cells. , Yet we have ... University, who has been exploring two “highly conserved? cell-signaling pathways ... we have a lot of common enemies, particularly soil-borne ...
Cached Biology News:Embryonic stem cells do better on bumpy nanoscale mattress 2Male circumcision reduces HIV risk, study stopped early 2Male circumcision reduces HIV risk, study stopped early 3Worms produce surprise insight into human fever 2
(Date:9/29/2014)... , Sept. 29, 2014 Research and ... Liquid Analyzer, Gas Analyzer, and Gas Chromatograph Market by ... Region - Global Trends & Forecast to 2013 - ... A process analyzer is a process analytical instrument that ... It has redefined the way by which companies carry ...
(Date:9/29/2014)... Transparency Market Research, in its report titled ‘Peptide ... Application - Cancer, Metabolic, CVS, CNS & others, by ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... market was worth US$14.1 billion in 2011 and is ... 8.7% CAGR. , The two main types of peptide ...
(Date:9/29/2014)... Mass. , Sept. 29, 2014  Atlas Venture, ... life sciences and technology innovation, today announced that ... Epizyme (NASDAQ: EPZM ), is joining the ... October 1, 2014. At Atlas, Rhodes will ... groundbreaking companies. He brings an accomplished record in company ...
(Date:9/29/2014)... Sept. 29, 2014 /PRNewswire/ - SQI Diagnostics Inc. (TSX-V: ... and commercializes proprietary technologies and products for advanced microarray ... Peter Winkley to Chairman of the Board of ... Ricks will continue to serve as a Director on ... the Company.  "We are very pleased ...
Breaking Biology Technology:Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 2Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 3Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 4Global Peptide Therapeutics Market to be Worth US$25.4 Billion by 2018: Transparency Market Research 2Global Peptide Therapeutics Market to be Worth US$25.4 Billion by 2018: Transparency Market Research 3Atlas Venture Names Jason Rhodes, Veteran Investor and President and CFO of Epizyme, As Partner on Life Sciences Investing Team 2SQI Diagnostics Announces New Chairman of Board of Directors 2
... 29 Tutogen Medical, Inc.,(Amex: TTG ), a ... (allograft) and animal (xenograft) tissue, announced today,that Guy L. ... the Roth Capital Partners New York Investor Conference on,Thursday, ... conference is,being held at The Westin NY at Times ...
... N.Y., Aug. 29 Emisphere,Technologies, Inc. (Nasdaq: ... been appointed to the position of Chief Financial ... CFO and Interim Chief Executive Officer,of Astralis, Ltd., ... Michael V. Novinski, President and Chief Executive Officer. ...
... PHRM ) today announced that the U.S. ... designation for oral Azacitidine in the,treatment of Myelodysplastic ... to facilitate the development and,expedite the review of ... or,life-threatening conditions and that demonstrate the potential to ...
Cached Biology Technology:Tutogen Medical, Inc. to Present at the Roth Capital Partners 2007 New York Conference 2Emisphere Technologies, Inc. Appoints Michael R. Garone chief financial officer 2Emisphere Technologies, Inc. Appoints Michael R. Garone chief financial officer 3Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes 2Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes 3Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes 4Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes 5Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes 6
...
... The new IKATUBE ULTRA TURRAX Tube Disperser System ... homogenizing system. It offers a cleaner, safer, and ... system processes sample volumes from 2 to 15 ... type, researchers can choose one of 4 different ...
...
... Triple-angle light scattering detector for ... digital signal processing hardware for two ... UV detectors. Also contains an analog ... interfacing to strip chart recorders. Includes ...
Biology Products: