Navigation Links
Chemical signaling helps regulate sensory map formation in the brain

Researchers from the University of Chicago have uncovered an important mechanism used by the developing brain to pattern nerve connections in the part of the brain that interprets visual signals. In the process, they have provided the first experimental evidence for a decades-old model of how nerve cells establish distant connections in a way that can consistently relay spatial information.

In the January 5, 2006, issue of the journal Nature, the researchers show that a gradient of a molecule known as Wnt3 counterbalances another force provided by the EphrinB1-EphB signaling system. The balance between these two signaling systems, they show, is necessary to establish the carefully controlled pattern of nerve connections required to convey spatial information in the correct order from the eye to the brain.

"This is the first biological validation of a computational model developed in the early 1980s that suggested that two such forces would be necessary to guide axons as they establish the connections that relay spatial information from one part of the nervous system to another," said study author Yimin Zou, Ph.D., assistant professor of neurobiology at the University of Chicago.

Neurobiologists refer to this type of neuronal connection ?in which the spatial order of neurons of one part of the nervous system is "copied" onto another -- as "topographic mapping." The term describes the creation of a coordinated connection that allows positional information from a grid of sensors, in this case the light-sensitive cells in the retina, to be smoothly and systematically transferred to their target, the structures in the brain that interpret information from the eyes.

"Without an orderly and faithful connection," said Zou, "information from the eyes could not be properly deciphered by the brain."

"Topographic maps are a very common wiring strategy in our brains," he said. Similar systems are thought to regulate other sensory system
'"/>

Source:University of Chicago Medical Center


Page: 1 2 3

Related biology news :

1. Chemicals in tattoo inks need closer scrutiny
2. Roots Engage in Underground Chemical Warfare
3. Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
4. Chemical band-aid prevents heart failure in mice with muscular dystrophy
5. Chemical compound inhibits tumor growth, size in new mouse study
6. T-rays: New imaging technology spotlighted by American Chemical Society
7. Chemical warfare agent detection technology used to treat lung disease
8. Chemical guidance of T cells leads to immunologic memory and long-term immunity
9. Chemical in many air fresheners may reduce lung function
10. Chemical tests of cell growth enter third dimension
11. Chemicals in brown algae may protect against skin cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chemical signaling helps regulate sensory map formation the brain

(Date:7/24/2014)... affect the connections between nerve cells and influence the ... of the brain that plays a significant role in ... of the study have been published in the journal ... active communication between nerve cells, known as neurons. For ... network where they constantly relay signals to one another. ...
(Date:7/24/2014)... in the United States, wildland managers often utilize the ... trees (ladder fuels). These cuttings and other post-logging ... danger in order to dispose of the material. To ... often cover all or part of the debris pile ... plastic, in order to keep water out. A recent ...
(Date:7/24/2014)... Neiker-Tecnalia is currently conducting research into the potato genes ... characterised by a reduction in rainfall and increased extremes ... the most resistant genes in order to create new ... conditions.The research is also seeking to find out how ... of greater drought and higher and lower temperatures. , ...
Breaking Biology News(10 mins):A protein couple controls flow of information into the brain's memory center 2A protein couple controls flow of information into the brain's memory center 3A protein couple controls flow of information into the brain's memory center 4Study gives new perspective on agricultural plastic, debris burning, and air quality 2Neiker-Tecnalia is researching the potato genes that best adapt to climate change 2
... Office of Naval Research (ONR) today launched a collaborative ... cellspart of a larger effort to use the smallest ... their missions. ONR currently has multiple ongoing projects ... tools and methods for creating new organisms with specific ...
... National Institutes of Health has awarded Dr. Daniel Geschwind, director ... five-year, $10 million grant to continue his research on the ... investigations to include the genetics of autism in African Americans. ... collaborative work by Geschwind and experts at other autism centers ...
... described small genetic changes that enable the H5N1 bird flu ... So far there have only been isolated cases of ... H5N1 virus can,t replicate efficiently in the nose. The new ... of controversial research published in 2012 which demonstrated that just ...
Cached Biology News:Recruiting engineered cells to work for warfighters 2Recruiting engineered cells to work for warfighters 3Autism in black and white: NIH grant helps scientist study disorder in African Americans 2Bird flu mutation study offers vaccine clue 2
(Date:7/24/2014)... 2014 Deep Research Report on ... professional and in-depth research report on Potassium Sulphate ... basic information, including its definition, classification, application, and ... covers the international market analysis, including China’s domestic ... macroeconomic environment & economic situation analysis, the influence ...
(Date:7/24/2014)... 2014 1000 balances – 4 steps ... customers’ weighing needs and expertly narrows down the mass ... scales or even terminals. , First, select the ... (or select readability instead) and define the accuracy – ... criteria narrows down the list to models that fit ...
(Date:7/24/2014)... BETHESDA, Md. , July 24, 2014  Spherix ... to the fostering and monetization of intellectual property, today ... for the period ending June 30, 2014 on Monday, ... conference call at 10 a.m. ET on Monday, August ... to be led by the company,s CEO, Anthony ...
(Date:7/24/2014)... The patent provides substantially greater ... results. It also enables true sample ID and ... reporting of high profile assays such as those ... growing area of biotechnology that includes DNA based ... companion diagnostics in personalized medicine. The new patent ...
Breaking Biology Technology:Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 3Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 4Spherix Schedules Shareholder Update Call 2New DNA-barcode Patent Virtually Eliminates False Test Results and Sample Mix-up 2
... are viewed as an enabler of increased research output at ... says he is making a pitch to investors to help ... side Milwaukee campus. , ,Santiago wants separate campuses for the ... and teaching, and he wants them in the proximity of ...
... - In its second acquisition of the past ... the Green Bay operations of Bedrock Managed Services & ... Milwaukee-based provider of information technology services, to establish a ... said it will maintain Bedrock's Green Bay office and ...
... Strategene Corp . will pay Third Wave Technologies ... of their patent dispute, and they have agreed to a ... ,The case, which was litigated in U.S. District Court for ... to the Federal Circuit in Washington, D.C., involves two companies ...
Cached Biology Technology:
...
... licensed, high throughput, water bath thermal cycler capable ... microplates. This equates to 9,216 reactions per run ... arm rapidly transfers a basket of plates between ... that are considerably faster than those of peltier ...
anti-Yan 8B12H9...
Proliferin (N-14)...
Biology Products: