Navigation Links
Cheap, rapid hand-held check for HIV

Political pressure has finally seen the price of antiretroviral therapy for HIV slashed in poorer countries. But a lack of cheap, simple diagnostics to enable doctors to use these complex treatments remains a stumbling block.

Now scientists from two New York universities believe they have the solution: a hand-held sensor that checks the health of a patient's immune system in seconds. At the moment it can take a week to get the same results back from the lab, "and that's if they don't get lost", says Glenda Gray, a consultant physician and head of perinatal HIV research at the University of the Witwatersrand in Johannesburg, South Africa.

The sensor measures the quantity of key immune cells called CD4+ cells in the blood. A gradual depletion of CD4+ cells, which orchestrate the immune response to tumours and infections, is a sure sign that HIV is damaging a person's health: some clinical definitions of AIDS say that once a person's CD4+ count falls below 200 cells per microlitre of blood, he or she has developed the condition.

Doctors rely on CD4+ measurements to decide when to start drug treatments and to gauge whether a patient is responding to them.

To make the device, researchers from Cornell University in Ithaca and the University at Albany coated electrodes with antibodies specific to CD4+ cells. When a small sample of blood is put onto a chip bearing these electrodes, the antibodies grab hold of the CD4+ cells. The captured cells then impede the flow of current across the electrodes, allowing the density of CD4+ cells to be calculated.

To check that only CD4+ cells were sticking to the electrodes the team added a label to blood samples consisting of a fluorescent dye tagged to a further set of antibodies specific for CD4+ cells. They then used an electron microscope to check which cells had been captured. By counting the captured cells, the researchers devised a scale linking electrical resistance with the density of
'"/>

Source:New Scientist Boston office


Page: 1 2

Related biology news :

1. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
2. Researchers develop rapid diagnostic tool for pathogen identification
3. Variation in HIVs ability to disable host defenses contributes to rapid evolution
4. New technique rapidly detects illness-causing bacteria
5. NASA satellite data provides rapid analysis of Amazon deforestation
6. Prions rapidly remodel good protein into bad, Brown study shows
7. Customized gene chip provides rapid detection of genetic changes in childrens cancer
8. A bugs life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
9. Scientists must offer solutions for conserving tropical forests in a rapidly changing world
10. Radiation-armed robot rapidly destroys human lung tumors
11. New strategy rapidly identifies cancer targets
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cheap rapid hand held check for HIV

(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ... Market Monitor: North America Perimeter Security Systems Market" ... http://photos.prnewswire.com/prnh/20130307/600769 The North American perimeter security ... 3.6% from 2014 to 2019. Although the U.S. market ... Canada is expected to grow at a ...
(Date:12/17/2014)... BELVOIR, Va. , Dec. 15, 2014 /PRNewswire-USNewswire/ ... efforts to make it easier to detect and ... chain. Today the agency started performing ... The capability will validate the authenticity of purchased ... chain. The new quality control measures will be ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... May 4 Strengthening its position as a ... PKI-based ePassport technology to help the Malaysian government (Jabatan Imigresen Malaysia) migrate ... , , , ... always prided itself on being at the forefront of border security," said ...
... available in German . , The hairs on ... 10 per cent decrease in fuel consumption. The plant has the ... water. Researchers at the University of Bonn, Rostock and Karlsruhe now ... the fern does this. Their results can possibly be used for ...
... Granada (UGR) have studied the natural history and conservation status ... balansae in Europe, a thorny bush that can grow ... be exclusive to Morocco. The team of scientists is calling ... of threatened species. In 2006, a research team from ...
Cached Biology News:Entrust Technology, Expertise Called on for Malaysian ePassport Project 2Entrust Technology, Expertise Called on for Malaysian ePassport Project 3Entrust Technology, Expertise Called on for Malaysian ePassport Project 4Bionic coating could help ships to economize on fuel 2Polygala balansae, a new bush to Europe, at risk of extinction in Spain 2
(Date:12/24/2014)... and NEW YORK , Dec. 23, ... open-label pilot study of mazindol in children with attention ... Therapy in December 2014 . The ... children with attention deficit/hyperactivity disorder" ( Konofal et al, ... Dec 1;8:2321-2332. eCollection 2014 ) shows that mazindol ...
(Date:12/22/2014)... GenomeDx Biosciences today announced that a new ... genomic test for prostate cancer, was able to predict ... radical prostatectomy without adjuvant therapy. Although rapid metastasis in ... tumor genomics to identify these men who have a ... advance. The study has been published online by ...
(Date:12/19/2014)... December 19, 2014 Bioject Medical ... and manufacturer of needle-free injection technology, today announced ... Immunomic Therapeutics, Inc. (“ITI”) for ITI to use ... its LAMP™ vaccine platform. , In the ... Worldwide license to the Biojector®-2000 that triggers based ...
(Date:12/19/2014)... REDWOOD CITY, Calif. , Dec. 19, 2014 ... , USA) announced today that they have been ... Technologies 1,2 is a privately held company that ... processing of next generation sequencing (NGS) data for the ... into the Roche Sequencing Unit, and will continue to ...
Breaking Biology Technology:Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... challenges , ,MADISON The white board in the ... their condition is a familiar scene in many hospitals. But ... best interest of the patient but still providing information to ... of a lecture given by Dennis Dassenko , UW ...
... of Wisconsin-Madison Department of Educational Psychology has teamed up ... Co-Lab to create new worlds in which people ... Department's Learning Sciences Program studies how human ... in UW-Madison's School of Education. "We have made digital ...
... EMD Biosciences Inc. , a supplier of premium ... it has formed a strategic partnership with The ... automation for life science applications. , ,This partnership ... and validate EMDs products on the Piccolo system, TAP's ...
Cached Biology Technology:The challenges of maintaining patient privacy and delivering secure clinical information 2The challenges of maintaining patient privacy and delivering secure clinical information 3University of Wisconsin team creates learning games 2University of Wisconsin team creates learning games 3EMD Biosciences partners with European biotech company 2
... Sigmas 10 Capillary Electrophoresis Running Buffer ... and high throughput demands of todays sequencing ... supplier of TBE to the gel-based sequencing ... large scale capacity to meet your buffer ...
... knockdown of all human, mouse, and ... Genomewide, predesigned siRNAs for a ... , Ready-to-use, convenient matching solutions for ... Cost-effective RNAi and downstream analysis ...
... Excalibur™ mid-, near- and far-infrared range FT-IR ... performance in their class. Yet all this ... Features: Highest-energy throughput: Having a larger ... compared to other conventional FT-IRs provides 300%,larger ...
... Rapid-Screen cDNA Library Panels were designed for ... sets of PCRs to identify the desired ... performed in a 96-well "Master Plate," where ... clones. Having identified the positive well(s) by ...
Biology Products: