Navigation Links
Change in gene may be underlying molecular defect in some colorectal cancers

moter methylation may qualify as a marker of the field defect in colorectal cancer," the authors write. In addition, "given the high lifetime risk of colorectal tumor development in the U.S. population, it is reasonable to propose testing to determine whether healthy persons with MGMT promoter methylation in normal colorectal mucosa are at higher risk of developing a colon tumor than those without such methylation."

In an editorial, Edward Giovannucci, M.D., Sc.D., of the Harvard School of Public Health, and Shuji Ogino, of Brigham and Women's Hospital, both in Boston, review the concept of the field defect (also called the field effect or field cancerization). They also raise several questions about how these findings may affect related areas of research, such as approaches to chemoprevention and "whether the reversal of DNA methylation in precancerous cells may prevent the development of new primary cancers in the same organ," they write.


'"/>

Source:Journal of the National Cancer Institute


Page: 1 2

Related biology news :

1. Iron Deficiency Sparks Dramatic Changes In Gene Expression
2. Scientists Propose Sweeping Changes to Naming of Bird Neurosystems to Acknowledge Their True Brainpower
3. FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
4. Some Brain Cells Change Channels To Fine-tune The Message
5. Some Brain Cells Change Channels
6. Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure
7. Is it Possible to Change Prescribing Habits?
8. Changes to embryos can elicit change in adult fish
9. Changes in amino acids in the 1918 influenza virus cut transmission
10. New mechanism underlying pain found
11. Revealing the machinery underlying the plastic juvenile brain
Post Your Comments:
(Date:3/20/2015)... 20, 2015 Research and Markets ... the "India Sensors Market Forecast and Opportunities ... The sensor market is projected to grow at ... Consumer electronics, automotive, industrial and healthcare sectors are ... country. In addition, adoption of MEMS technology in ...
(Date:3/20/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) has announced ... Business Report" report to their offering. This ... Thousands. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... America . Annual estimates and forecasts are ...
(Date:3/17/2015)... 2015 MedNet Solutions , a ... study management systems, is pleased to announce that ... Outsourcing in Clinical Trials Southeast conference – March ... excellent forum for MedNet to showcase iMedNet ... (SaaS) eClinical technology platform. We strongly ...
Breaking Biology News(10 mins):India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
... of Toronto and the Swiss Federal Institute of Technology ... exotic plants will likely eliminate native plants growing in ... A study published in Proceedings of the National ... that invasive plants are not problematic are often based ...
... January 2013) The microbial communities that reside in the ... are an expanding area of research full of exciting discoveries ... on the most recent advances in the field, scientists and ... For Health World Summit, which is hosted this year by ...
... changed diabetes from a death sentence to a chronic ... Case Western Reserve University School of Medicine announced a ... lives of people managing diabetes. After decades of ... international group of scientists finally found a definitive answer: ...
Cached Biology News:Invading species can extinguish native plants despite recent reports 2After decades of research, scientists unlock how insulin interacts with cells 2After decades of research, scientists unlock how insulin interacts with cells 3
(Date:4/23/2015)...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced ... 2015 results before the Nasdaq market opens on Thursday, ... call and webcast to discuss its financial results and ... at 8:00 a.m. Eastern Time (5:00 a.m. Pacific Time). ... by dialing 866-952-1906 (US) or 785-424-1825 (International) using the ...
(Date:4/23/2015)... , April 23, 2015  Cryoport, Inc. ... cryogenic logistics solutions for the life sciences industry, ... its cryogenic logistics solutions within the animal husbandry ... Yancey Farms to support the shipment of equine ... Sport horse Stallions. Animal husbandry ...
(Date:4/23/2015)... Glemser Technologies is ... Enterprise Content Division (ECD) Certified Solution Partner to ... for Life Sciences Solution Suite . The accreditation ... to provide life sciences companies of all sizes ... EMC Documentum Solution Suite offers four modules: Quality ...
(Date:4/23/2015)...  Propanc Health Group Corporation (OTCBB: PPCH) is ... development of cancer treatments for patients with pancreatic ... PRP, a patented formulation consisting of two pro-enzymes, ... the enzyme amylase designed to synergistically enhance anti-cancer ... anti-cancer agents working in combination with pro-enzymes, which ...
Breaking Biology Technology:Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Glemser Earns Accreditation for Life Sciences Solution Suite 2Early Stage BioTech offers Plenty of Risk; Propanc Health Group Analyst Brief Issued by BrokerBank Securities, Inc. 2
... Nov. 29 As part of an ongoing ... maximize commercial,impact of their products, Premier Research Group ... industry-leading expertise in its core,service areas into a ... expertise within the group closely matches Premier Research,s ...
... Multi-stakeholder initiative will use health information technology ... safety efforts across,the U.S., WASHINGTON, Nov. ... announced today the formation of an innovative,research ... patients. The eHI,Connecting Communities for Drug Safety ...
... Prometheus Laboratories Inc., a,specialty pharmaceutical company ... exclusive license agreement to develop and commercialize ... North America from,Alizyme Therapeutics Limited, a wholly ... unique competitive profile based on Alizyme,s proprietary,COLAL(R) ...
Cached Biology Technology:Product Development Timelines and Commercialization Strategy Are Focus of New Group at Premier Research 2eHealth Initiative Foundation Launches Collaborative Research Effort to Improve Drug Safety 2eHealth Initiative Foundation Launches Collaborative Research Effort to Improve Drug Safety 3eHealth Initiative Foundation Launches Collaborative Research Effort to Improve Drug Safety 4eHealth Initiative Foundation Launches Collaborative Research Effort to Improve Drug Safety 5eHealth Initiative Foundation Launches Collaborative Research Effort to Improve Drug Safety 6Prometheus Licenses COLAL-PRED(R) From Alizyme 2Prometheus Licenses COLAL-PRED(R) From Alizyme 3Prometheus Licenses COLAL-PRED(R) From Alizyme 4
...
...
... XL provides RS232/Serial data collection and automation ... Complete instrument integration with Microsoft Excel ... balances, pH meters, titrators, density meters, force ... and serial instruments can be added and ...
DNA sequencing - plasmids or PCR fragments, 3-7 working days service....
Biology Products: