Navigation Links
Cell barrier shows why bird flu not so easily spread among humans

em, (cell) receptors for avian viruses, including avian H5N1 viruses, are present," explains Kawaoka, who also holds an appointment at the University of Tokyo. "But these receptors are rare in the upper portion of the respiratory system. For the viruses to be transmitted efficiently, they have to multiply in the upper portion of the respiratory system so that they can be transmitted by coughing and sneezing."

The upshot of the new finding, says Kawaoka, a professor of pathobiological sciences at the UW-Madison School of Veterinary

Medicine, is that existing strains of bird flu must undergo key genetic changes to become the type of flu pathogen most feared by biomedical scientists.

"No one knows whether the virus will evolve into a pandemic strain, but flu viruses constantly change," Kawaoka says. "Certainly, multiple mutations need to be accumulated for the H5N1 virus to become a pandemic strain."

The finding suggests that scientists and public health agencies worldwide may have more time to prepare for an eventual pandemic of avian influenza. Periodically, animal forms of influenza such as bird flu evolve to become highly contagious human pathogens.

Most scientists agree a pandemic of avian influenza will occur at some time. The worst-case scenario would be a form of influenza similar to the strain of 1918 that killed between 30 million and 50 million people globally.The new work may also help scientists keep track of evolving strains of influenza and provide earlier warning of potential pandemics. For the H5N1 strain of flu virus to evolve to a pathogen easily transmissible from one human to another, changes need to occur in the virus' hemagglutinin surface protein -- a molecule embedded in the virus membrane -- to recognize human receptors, Kawaoka says.

"Mutations in the hemagglutinin for avian H5N1 viruses to recognize human receptors are needed for the virus to become a pandemic strain," Kawaoka explains.

'"/>

Source:University of Wisconsin-Madison


Page: 1 2 3

Related biology news :

1. Slipping past the blood brain barrier: Research shows potential treatment for brain cancer
2. Primate virus jumps species barrier to humans for first time in Asia
3. Divergent mating systems and parental conflict as a barrier to hybridization in flowering plants
4. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
5. “Nano-scissors?laser shows precise surgical capability
6. Clam embryo study shows pollutant mixture adversely affects nerve cell development
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. Study shows nanoshells ideal as chemical nanosensors
9. Gene vaccine for Alzheimers disease shows promising results
10. Flocking together: Study shows how animal groups find their way
11. New drug shows promise as powerful anticancer agent
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cell barrier shows why bird flu not easily spread among humans

(Date:12/5/2014)... , Dec. 4, 2014  Tute Genomics, a leader ... million in Series A1 funding led by UK-based Eurovestech. ... participated in the investment round. "We are ... community adopts next-generation sequencing and seeks new approaches for ... Reid Robison , MD MBA, and CEO of Tute ...
(Date:12/3/2014)... 2014   Marvin Test Solutions , a ... for military, aerospace, and manufacturing organizations, today announced ... TS-900 PXI semiconductor test platform . The ... systems to customers at a fraction of the ... ATE. "Our semiconductor customers asked ...
(Date:11/21/2014)... November 18, 2014 According to ... by Systems (Video, RFID, Access Control, Intrusion Detection, Parking ... Banks, Government), Component Service Geography - Global Forecasts to ... is projected to be around $25 Billion in 2014 ... growing at a CAGR of 8.69%. Browse ...
Breaking Biology News(10 mins):Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... (April 23, 2012) The benefits of breast milk are well ... remains a mystery. A new study in the Journal ... of cancer-fighting TNF-related apoptosis inducing ligand (TRAIL) in human milk, ... , Researchers took samples of colostrum, the first ...
... Biology 2012, Dr. Blake Rasmussen and colleagues presented a ... vs. Whey Protein Ingestion on Muscle Protein Synthesis Following ... that a protein blend (combination of soy, whey and ... muscle. Specifically, the blend of proteins in this study ...
... Tampa, Fla. (April. 23, 2012) Researchers interested ... fat and high cholesterol (HFHC) diet on implanted fetal ... the HFHC diet elevated microglial activation and reduced neuronal ... inflammatory response in the central nervous system, they found ...
Cached Biology News:New study finds a protein combination is best to consume post-workout for building muscle 2Study finds 'Western diet' detrimental to fetal hippocampal tissue transplants 2
(Date:12/19/2014)... REDWOOD CITY, Calif. , Dec. 19, 2014 ... , USA) announced today that they have been ... Technologies 1,2 is a privately held company that ... processing of next generation sequencing (NGS) data for the ... into the Roche Sequencing Unit, and will continue to ...
(Date:12/19/2014)... Today, TiFiber, Inc. ... facility and future company headquarters in Fort Smith, ... materials that safely and effectively control dangerous microorganisms. ... its historic, strong support for manufacturing, but also ... edge, technology-based companies such as TiFiber. , ...
(Date:12/19/2014)... Boston, MA (PRWEB) December 18, 2014 ... software, announced the appointment of Siri Bryant as the ... the new Director of Core Implementations. These two new ... provide outstanding customer service by ensuring that iLab continues ... , “In the last four years, iLab has been ...
(Date:12/19/2014)...  Decision Resources Group finds that the ... moderately through 2023 as the aging population, increasing adoption ... biomaterials all spur procedure volumes. Growth will be particularly ... and India , where ... for a larger proportion of the population. ...
Breaking Biology Technology:Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3
... ... in Eighteen Platform and Poster Sessions. Its EPA-approved technologies will be widely highlighted during ... 24-27 in Monterey, California. , ... Los Angeles, CA (Vocus) May 1, 2010 -- The Adventus Group, a ...
... FREISING-WEIHENSTEPHAN, Germany , April 30, 2010 ... proprietary PRS-110 Anticalin(R),compound, which targets the c-Met receptor, demonstrating ... model. The results provide an,indication that an Anticalin approach ... value in treating cancer. A broad body of,research has ...
... chemistry classes often start off with learning how to ... Mellon University chemistry professor David Yaron, seems to be, ... interesting, you may get to use it later." ... students to design and carry out experiments more like ...
Cached Biology Technology:ADVENTUS Bioremediation Technologies Highlighted at Battelle Symposium. 2ADVENTUS Bioremediation Technologies Highlighted at Battelle Symposium. 3ADVENTUS Bioremediation Technologies Highlighted at Battelle Symposium. 4Pieris Announces Positive Preclinical Data on c-Met Anticalin Drug Program 2Virtual lab wins prestigious prize awarded by Science 2Virtual lab wins prestigious prize awarded by Science 3Virtual lab wins prestigious prize awarded by Science 4
... DNA Engine Dyad thermal cycler is ... (PCR). The chassis accommodates a variety ... assemblies), which hold different types and ... graphical programming with point-and-click navigation. Peltier ...
MiniCycler thermal cycler with Hot Bonnet heated lid, holds 25x0.2ml tubes...
For demonstration of Helicobacter pylori...
... FLISP Assay with SR-101 Labeled Substrates ... • Accurately measure serine protease activation ... • B-Bridge's FLISP Kits utilize cell-permeable, ... (FLISPs) to measure chymotrypsin-like activity in ...
Biology Products: