Navigation Links
Cell barrier shows why bird flu not so easily spread among humans

em, (cell) receptors for avian viruses, including avian H5N1 viruses, are present," explains Kawaoka, who also holds an appointment at the University of Tokyo. "But these receptors are rare in the upper portion of the respiratory system. For the viruses to be transmitted efficiently, they have to multiply in the upper portion of the respiratory system so that they can be transmitted by coughing and sneezing."

The upshot of the new finding, says Kawaoka, a professor of pathobiological sciences at the UW-Madison School of Veterinary

Medicine, is that existing strains of bird flu must undergo key genetic changes to become the type of flu pathogen most feared by biomedical scientists.

"No one knows whether the virus will evolve into a pandemic strain, but flu viruses constantly change," Kawaoka says. "Certainly, multiple mutations need to be accumulated for the H5N1 virus to become a pandemic strain."

The finding suggests that scientists and public health agencies worldwide may have more time to prepare for an eventual pandemic of avian influenza. Periodically, animal forms of influenza such as bird flu evolve to become highly contagious human pathogens.

Most scientists agree a pandemic of avian influenza will occur at some time. The worst-case scenario would be a form of influenza similar to the strain of 1918 that killed between 30 million and 50 million people globally.The new work may also help scientists keep track of evolving strains of influenza and provide earlier warning of potential pandemics. For the H5N1 strain of flu virus to evolve to a pathogen easily transmissible from one human to another, changes need to occur in the virus' hemagglutinin surface protein -- a molecule embedded in the virus membrane -- to recognize human receptors, Kawaoka says.

"Mutations in the hemagglutinin for avian H5N1 viruses to recognize human receptors are needed for the virus to become a pandemic strain," Kawaoka explains.

'"/>

Source:University of Wisconsin-Madison


Page: 1 2 3

Related biology news :

1. Slipping past the blood brain barrier: Research shows potential treatment for brain cancer
2. Primate virus jumps species barrier to humans for first time in Asia
3. Divergent mating systems and parental conflict as a barrier to hybridization in flowering plants
4. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
5. “Nano-scissors?laser shows precise surgical capability
6. Clam embryo study shows pollutant mixture adversely affects nerve cell development
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. Study shows nanoshells ideal as chemical nanosensors
9. Gene vaccine for Alzheimers disease shows promising results
10. Flocking together: Study shows how animal groups find their way
11. New drug shows promise as powerful anticancer agent
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cell barrier shows why bird flu not easily spread among humans

(Date:12/17/2014)... and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ) has announced ... Home Button Synaptics Fingerprint Sensor Technology Analysis" report ... Based on a totally different sensing ... first time a fingerprint sensor in its product. ...
(Date:12/17/2014)... fundamentally transforming the travel experience and nowhere is this ... decade, ePassports, biometric readers, and secure document scanners have ... via eGates and Automated Passport Control (APC) Kiosks at ... across the globe. According to ...
(Date:12/11/2014)... Minn. , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... than 30 researchers today gave a score to every coastal ... oceans, which showed the United States as being slightly above ... concerns. The analysis, published in the journal Nature ... separate categories such as clean water, biodiversity, food provision, carbon ...
... in the journal Conservation Biology , high levels ... the ability of critically endangered North Atlantic right whales ... From 2007 until 2010, scientists from Stellwagen Bank National ... Fisheries Science Center, and Marine Acoustics Inc. used an ...
... , EAST LANSING, Mich. A professor at Michigan ... new method of removing phosphorous from our wastewater ... country. In addition, Steven Safferman, an associate professor ... Ohio, based-MetaMateria Technologies, are devising a cost-effective way of ...
Cached Biology News:Rating of ocean health shows 'room for improvement' 2NOAA: Underwater noise decreases whale communications in Stellwagen Bank sanctuary 2New method to remove phosphorous from wastewater 2
(Date:1/22/2015)... 2015 zFlo Motion , a US ... an exciting product from a new partner. STT-Systems ... the past 15 years, with offerings in the optical-motion capture, ... IMU system (inertial measurement unit), iSen, is opening eyes around ...
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 ... technologies such as the Bioruptor® and complete solutions ... system for chromatin immunoprecipitation, alleviating the need for ... and controls needed for ChIP of histones or ...
(Date:1/22/2015)... 22, 2015   GenoSpace , a precision medicine software company ... the broad use of genomic, imaging and other biomedical data ... Michelle Munson , CEO of Aspera, an IBM Company, ... - http://photos.prnewswire.com/prnh/20150122/170713 "We are pleased ...
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 PlasmaTech Biopharmaceuticals, ... in critical areas, announced the closing of an underwritten public ... purchase up to an aggregate 3,500,000 shares of common stock, ... per warrant.  The warrants have a per share exercise price ...
Breaking Biology Technology:3D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2GenoSpace Expands Board with Appointment of Michelle Munson 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3
... German . Researchers from Helmholtz-Zentrum Berlin ... are using electric fields to manipulate the property of electrons ... not only improve random access memory in computers, it could ... new kind of memory exploits a phenomenon called "tunnel magnetoresistance" ...
... , BIRMINGHAM, Ala. , Jan. 19 ... comes to cholesterol. According to a new study, a lipoprotein in ... be labeled "bad cholesterol." The landmark study Genetic Variants Associated ... the New England Journal Of Medicine provides the strongest ...
... BANGALORE, India , January 19 , ... A team of cardiac experts led by Dr. N S Devananda, ... performed a major open heart surgery on a 2-year-old baby from Nigeria ... of,Fallot or complex blue baby syndrome. , " Baby ...
Cached Biology Technology:Data at the end of the tunnel 2New Study: Lp(a) Joins LDL as Heart Disease Risk Factor 2New Study: Lp(a) Joins LDL as Heart Disease Risk Factor 32-Year-old Baby With Complex Heart Deformity Undergoes Major Open Heart Surgery at Wockhardt Hospitals, Bangalore - (now a Network Hospital of Fortis) Without any Blood Transfusion 22-Year-old Baby With Complex Heart Deformity Undergoes Major Open Heart Surgery at Wockhardt Hospitals, Bangalore - (now a Network Hospital of Fortis) Without any Blood Transfusion 3
The external laser upgrade for the Molecular Imager FX adds a 635 nm external laser; the 555 nm long pass filter is replaced with a 605 nm band pass filter to distinguish Cy5 from 532 nm excitable dy...
... is designed for fast and easy purification ... and tissues. The bead beating technology used ... procedures such as CTAB, phenol, or chloroform ... is not necessary - purified DNA is ...
The filter 530DF28 for the Molecular Imager FX is a band pass filter for ECL Plus, AttoPhos, SYBR Green, Alexa Fluor 488, FITC, Cy2, and Pro-Q Emerald dyes....
... APO-DIRECT is a single-step staining method for ... by flow cytometry. The kit contains all ... in cells including: positive and negative control ... and rinsing buffers for processing individual steps ...
Biology Products: