Navigation Links
Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

ark areas that indicate the presence of the MRI reporter.

"Our technology is adaptable to monitor gene expression in many tissue types. You could link this MRI reporter gene to any other gene of interest, including therapeutic genes for diseases like cancer and arthritis, to detect where and when they are being expressed," Ahrens said.

Existing methods used to image gene expression have limitations, according to Ahrens. Some methods cannot be used in living subjects, fail to image cells deep inside the body or don't provide high-resolution images. Other approaches using MRI are not practical for a wide range of applications.

Ahrens and his colleagues constructed a gene carrier, or vector, that contained a gene for the MRI reporter. They used a widely studied vector called a replication-defective adenovirus that readily enters cells but doesn't reproduce itself. Ahrens injected the vector carrying the MRI reporter gene into brains of living mice and imaged the MRI reporter expression periodically for over a month in the same cohort of animals. The research showed no overt toxicity in the mouse brain from the MRI reporter.


'"/>

Source:Carnegie Mellon University


Page: 1 2

Related biology news :

1. Robot-based system developed at Carnegie Mellon detects life in Chiles Atacama desert
2. Green catalyst destroys pesticides and munitions toxins, finds Carnegie Mellon University
3. Carnegie Mellon University research reveals how cells process large genes
4. Carnegie Mellon cyLab researchers work to develop new red tide monitoring
5. Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
6. Carnegie Mellon scientists create PNA molecule with potential to build nanodevices
7. Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
8. Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level
9. Carnegie Mellon scientists show brain uses optimal code for sound
10. DNA conclusive yet still controversial, Carnegie Mellon professor says
11. Teens unaware of sexually transmitted diseases until they catch one, Carnegie Mellon study finds
Post Your Comments:
(Date:7/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/km7m5t/natural_language ... "Natural Language Processing Market by Type (Rule-Based, Statistical, ... Image Recognition) - Worldwide Forecast to 2020" ... vendors occupying the market are 3M, Apple, Dolbey ... Solutions, SAS Institute Inc., Verint Systems among various ...
(Date:6/30/2015)... 2015 Genisphere announced Tom ... help further develop Genisphere,s therapeutics capabilities and portfolio. Mr. ... spent much of the last 25 years in leadership ... and Johnson & Johnson. Tom started his career in ... Corporate Finance. He graduated from Dartmouth College with a ...
(Date:6/25/2015)... 25, 2015  Imagine a tool specifically designed to ... happier life. That,s exactly what USANA,s True Health ... cutting-edge, portable health program provides a personalized approached to ... improve your lifestyle and nutrition. At ... Wednesday night, USANA,s THA was honored with the Industry ...
Breaking Biology News(10 mins):Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2
... JUPITER, FL January 25, 2011 Embargoed by ... Scientists from the Florida campus of The Scripps Research ... an individual,s vulnerability to the addictive properties of nicotine. The ... study appeared January 30, 2011, in an advance, online issue ...
... of antibiotics that followed it, streptococcus bacteria have remained ... reason: the superb evolutionary skills of this pathogen to ... published this week in Science , scientists from ... genome sequencing to identify the precise steps in the ...
... of the journal Science , UC Davis expert ... also true, and explores what that might mean to ... vice-versa. A classic example of ecology influencing evolution ... In this species, larger beaks dominated the population after ...
Cached Biology News:Scripps Research scientists reveal key mechanism governing nicotine addiction 2Scripps Research scientists reveal key mechanism governing nicotine addiction 3New research traces evolutionary path of multidrug-resistant strep bacteria 2New research traces evolutionary path of multidrug-resistant strep bacteria 3
(Date:7/28/2015)... Israel , July 28, 2015 ... medicine company utilizing its proprietary plant-based rhCollagen technology ... Shurtz has been appointed Senior Director of Business ... (Photo: http://photos.prnewswire.com/prnh/20150728/246955 ) , ... in marketing, regulatory and business strategy. Prior to ...
(Date:7/27/2015)...  Amgen (NASDAQ: AMGN ) today announced that ... Thursday, July 30, 2015, after the close of the ... a conference call with the investment community at 2 ... be Robert A. Bradway , chairman and chief ... team. Live audio of the conference call ...
(Date:7/27/2015)... /PRNewswire/ - Quest PharmaTech Inc. (TSX-V: QPT) ("Quest" or ... for the treatment of cancer, today provides the following ... closed a $1,000,000 unit offering private placement.  This financing ... the Company at a price of $0.06 per unit.  ... one common share purchase warrant.  Each whole warrant is ...
(Date:7/27/2015)... ... July 27, 2015 , ... Production of high tenacity filament yarn of viscose ... the EU. For instance, it surpassed the EUR 106 million mark (in value terms) ... Germany is a major producer, while Italy is a key consumer. , The ...
Breaking Biology Technology:CollPlant Names Shomrat Shurtz Senior Director of Business Development 2Amgen Announces Webcast of 2015 Second Quarter Financial Results 2Quest PharmaTech Closes $1,000,000 Private Placement 2High Tenacity Filament Yarn of Viscose Rayon Consumption to Grow Swiftly in the EU, Forecasts BAC Reports in New Study Available at MarketPublishers.com 2
... N.C., Aug. 30, 2011 Savvier consumers and competition ... market entry or during brand maturity, more elusive.  At ... ability of cost-efficient Public Relations to support pharmaceutical brand ... Public Relations to support their brands, recent field research ...
... 30, 2011 Avantra Biosciences Corporation today announced ... to Courtagen Life Sciences, Inc.  The company will ... proteomics portfolio, which includes the Avantra Biomarker System. ... quantitative multiplex protein assays using catalog or custom ...
... Aug. 30, 2011 ProteinSimple today introduced a revolutionary new ... Simple Western is a complete reinvention of the Western Blot, ... the first time in 30 years, researchers have access to ... The Western Blot was invented in 1979 and to ...
Cached Biology Technology:Using Public Relations to Launch, Grow, and Extend Pharmaceutical and Biotech Brands 2ProteinSimple Reinvents the Western Blot 2