Navigation Links
Cancer stem cells linked to radiation resistance

t.

In another set of experiments, the researchers treated both the test animals and the cell cultures with a drug, called debromohymenialdisine, which is known to inhibit the proteins involved in the activation process. They added the drug before and after radiation treatment and measured the number of surviving cancer stem cells.

They found that administering the drug before radiation did little to change the number of cancer stem cells, but giving the drug in conjunction with radiation appeared to halt the resistance of cancer stem cells to radiation. This finding, the researchers said, suggests that use of a checkpoint inhibitor during radiation ruins the cells' potential to repair themselves and increases the likelihood that the cells will die.

"Our findings show one pathway in cancer stem cells that promotes the radiation resistance of glioblastomas," said Rich. "Treatments that target DNA damage checkpoint response in cancer stem cells may overcome the radiation resistance and eventually allow us to help even greater numbers of cancer patients."
'"/>

Source:Duke University Medical Center


Page: 1 2 3

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Jump-starting T Cells In Skin Cancer
3. Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
4. Fox Chase Cancer Center scientists identify immune-system mutation
5. Breakthrough Microarray-based Technology for the Study of Cancer
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
8. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
9. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
10. New Breast Cancer Test Could Save Lives
11. Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

Post Your Comments:
(Date:11/23/2009)... , , , , , , , ...Dr Andrew Marshall, from the Environment Departmen...ry of Kinyongia magomberae and his wider work in...e information. , , , , , ... , , , , , , A new species of chamele...
(Date:11/23/2009)...vironmental irritants such as air pollution and ci...ublished today in the American Journal of Respira...he study, from Imperial College London and the Uni...de the lungs that can trigger coughing when a pers...They suggest that their findings may ultimately le...
(Date:11/23/2009)...man . , Not just birds, but also a few speci...hers at Princeton University in the U.S. and at th...ll, Germany studied the migratory behaviour of the...pertilionidae" with the help of mathematical model...s well as long distances of various kinds of bats ...
Breaking Biology News(10 mins):New chameleon species discovered in East Africa 2New chameleon species discovered in East Africa 3Research reveals exactly how coughing is triggered by environmental irritants 2We're off then: The evolution of bat migration 2Announcing Companies to Present at the 7th Annual MidAmerica Healthcare Venture Forum 5079 1Announcing Companies to Present at the 7th Annual MidAmerica Healthcare Venture Forum 5079 2Announcing Companies to Present at the 7th Annual MidAmerica Healthcare Venture Forum 5079 3Announcing Companies to Present at the 7th Annual MidAmerica Healthcare Venture Forum 5079 4Kensey Nash to Present at the JMP Securities Fourth Annual Healthcare Focus Conference 58495 1AFGE Expresses Concern Over FEHBP Premium Increases 58493 1
...Researchers at Virginia Commonwealth University,s ...ased, anti-cancer agent able to overcome acquired ...bsorbed into cancer cells and then attacking the D... researchers design a new generation of anti-cance...ce resistance and side effects and expand the rang...
...Using powerful computer tools and cryo-electron mi...ne unmasked the secrets of a tiny virus that infec... better understanding of a variety of viruses that...ears in and on the cover of the current issue of t...BCM department of biochemistry and molecular biolo...
...Low-grade uranium ore is nicknamed "yellowcake" fo...ave another name: Leetso, or "yellow monster." , T...th uranium mining that started in the 1940s and co...math came illnesses such as lung cancer among mine...tion among people who live on that land. , The Na...
Other Biology News:VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum 2Unraveling the viral mechanism 2Study may help slay 'Yellow Monster' 2Study may help slay 'Yellow Monster' 3
(Date:11/19/2009)...e their cell phones and other personal electronics...e by UC San Diego engineers could lead to carbon n...his. , In recent research, published in Applie... in the UCSD Department of Mechanical and Aerospac...efer, have found that artificially introduced defe...
(Date:11/19/2009)... Spherix Incorporated (Na...iabetes therapy, and a provider of technical and r... biotechnology and pharmaceutical companies, annou...million registered direct placement to institution...ck and warrants to purchase up to 1,104,348 additi...
(Date:11/19/2009)...9 MONITORING FORCE GmbH,announced ...serin in the,indication treatment-relevant levodop...phan drug status designation with the European Med...is a complication of the mainstay,treatment in adv...those,affected, since it may be disabling for the ...
(Date:11/19/2009)...y latest award for revolutionary hearing aid. , ... 16, 2009 -- Popular Science Magazine has named th...nSound Medical a winner of its coveted Best of Wha...nbsp;  Chosen from thousands of entrants...canal for up to four months while providing natura...
Breaking Biology Technology:Nanotube defects equal better energy and storage systems 2Spherix Announces the Closing of $6.3 Million Registered Direct Offering 2Spherix Announces the Closing of $6.3 Million Registered Direct Offering 3MONITORING FORCE GmbH Requests Acknowledgment of Flibanserin as "Orphan Drug" 2Popular Science Awards Lyric “Invisible” Hearing Aid 2009 “Best of What's New” Award 2Popular Science Awards Lyric “Invisible” Hearing Aid 2009 “Best of What's New” Award 3
..., Oct. 2 Northwest,Biotherapeutics, Inc. (OTC Bul...oday that Anthony P. Deasey, 58, has been appointe...e and Chief Financial Officer, and,has been electe...T, from November 2000 to September 2007 Mr. Deasey...al and Chief Operating,Officer of Celsion Corporat...
...., Oct. 1 CorVel Corporation,(Nasdaq: CRVL ), a ...anagement services, announced the addition of over...tional CorCare Preferred Provider Network,effectiv...ions are the,result of a new partnership with Inte...rsburg, FL. With more than 5,500 hospitals and ov...
... 1 Biomaxx Systems Inc. (Other,OTC: BMXSF), is pl...ership,with Bioenergy Australia for 2007. BioMaxx ...ss opportunities created in Australia as a result ...ergy Australia is a,government and industry forum ...lutions. Dr. Stephen Schuck, the executive manage...
Other Biology Technology:Northwest Biotherapeutics, Inc. Announces Appointment of Chief Financial Officer 2CorVel Corporation Medical Provider Network Adds New Providers to Increase Savings and Improve Access to Care 2CorVel Corporation Medical Provider Network Adds New Providers to Increase Savings and Improve Access to Care 3Biomaxx Systems Inc. Renews Membership With Bioenergy Australia 2
...ecombinant human protein produced in E. coli and i... type enzymes. The mode of inhibition is noncompe...1 ratio. The enzyme has been shown to inactivate R...tion of the ribonuclease inhibitor has been shown ...
...ombinant protein that has been shown to help maint...A by reverse transcription, in vitro RNA transcrip...hibitor tightly binds RNases in a 1:1 ratio. It in...RNase A, RNase B, RNase C, and human placental RNa...
FastStart High Fidelity PCR System, dNTPack (Not available in US) from Roche Applied Science
RNase Inhibitor from Applied Biosystems
Biology Products: