Navigation Links
Cancer-killing invention also harvests stem cells

Associate Professor Michael King of the University of Rochester Biomedical Engineering Department has invented a device that filters the blood for cancer and stem cells. When he captures cancer cells, he kills them. When he captures stem cells, he harvests them for later use in tissue engineering, bone marrow transplants, and other applications that treat human disease and improve health. With Nichola Charles, Jared Kanofsky, and Jane L. Liesveld of the University of Rochester, King wrote about his discoveries in "Using Protein-Functionalized Microchannels for Stem Cell Separation," Paper No. ICNMM2006-96228, Proceedings of the ASME, June 2006. King's team includes scientists at StemCapture, Inc., a Rochester company that bought the University patent for King's technique in November 2005 to build the cancer-killing and stem cell-harvesting devices. The technique can be used in vivo, meaning a device is inserted in the body, or in vitro, in which case the device resides outside of the body ?either way, the device kills cancer cells and captures stem cells, which grow into blood cells, bone, cartilage, and fat.

When King was working at the University of Pennsylvania from 1999 to 2001, one of his labmates discovered that bone marrow stem cells stick to adhesive proteins called selectins more strongly than other cells -- including blood cells -- stick to selectins. When King came to the University of Rochester in early 2002, he started studying the adhesion of blood cells to the vascular wall, the inner lining of the blood vessels. During inflammation, the vascular wall presents surface selectins that adhere specifically to white blood cells. These selectins cause the white blood cells to roll slowly along the vascular wall, seeking signals that tell them to crawl out of the bloodstream. This is how white blood cells migrate to bacterial infections and tissue injuries. King set out to find a way to duplicate this natural process.

First, he no
'"/>

Source:School of Engineering and Applied Sciences University of Rochester


Page: 1 2 3 4

Related biology news :

1. Restaurant seafood prices since 1850s help plot marine harvests through history
2. Wisconsin scientists grow critical nerve cells
3. Spleen may be source of versatile stem cells
4. Elusive HIV shape change revealed; Key clue to how virus infects cells
5. Scientists rid stem cell culture of key animal cells
6. Genetically modified natural killer immune cells attack, kill leukemia cells
7. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
8. Tiny scaffolding allows stem cells to become working fat cells
9. Researchers devise way to mass-produce embryonic stem cells
10. New insight into regulation of blood stem cells
11. Researchers unlock mechanism creating jigsaw puzzle-like plant cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cancer killing invention also harvests stem cells

(Date:8/19/2014)... release is available in German . ... inherently intermittent energy sources. If a large amount of electricity ... future, excess energy will have to be stored during productive ... existing storage capacities are far from adequate for the purpose. ... One important focus lies on battery systems that used to ...
(Date:8/19/2014)... devised a new implantable tissue scaffold coated with bone ... weeks. When applied to bone injuries or defects, this ... bone that looks and behaves just like the original ... a dramatic improvement over the current standard for treating ... of the patient,s body a painful process that ...
(Date:8/19/2014)... in college biology and other science courses are ... ways, and now they have a new textbook ... Life Sciences," published this month by Princeton Press ... for Mathematical and Biological Synthesis (NIMBioS), teaches readers ... be used to explore and explain biological phenomena. ...
Breaking Biology News(10 mins):Asian inventions dominate energy storage systems 2Asian inventions dominate energy storage systems 3Engineering new bone growth 2Engineering new bone growth 3New textbook introduces undergraduates to mathematics for the life sciences 2
... Shakespeare. In humans, nature may be less than half of ... researchers has found. In the first study of its ... explain why human birds of a feather flock together, but ... upon the social environment in which individuals interact with one ...
... Stanford University scientists have built the first solar cell made ... used in photovoltaic devices today. The results are ... ACS Nano . "Carbon has the potential to ... author Zhenan Bao, a professor of chemical engineering at Stanford. ...
... stem cells such as regenerating damaged tissues or organs ... past decade. While these types of applications are exciting, it ... immediate impact of stem cells on human health will most ... drugs. , The ability to generate stem cells by reprogramming ...
Cached Biology News:Social factors trump genetic forces in forging friendships, CU-led study finds 2Stanford scientists build the first all-carbon solar cell 2Stanford scientists build the first all-carbon solar cell 3The role of stem cells in developing new drugs 2
(Date:8/18/2014)... China is increasingly being recognized as ... industry. Clinicaltrial.gov statistics highlight the popularity of China ... a high increase in infectious diseases; a rapid ... of patients and a track record of rapid ... also presents challenges for the clinical research industry ...
(Date:8/16/2014)... 2014 Firms in the ... and advisory services to businesses, government bodies and ... services are highly diverse as operators assist a ... from geological and geophysical consulting services to risk ... past five years, the recovery of the Canadian ...
(Date:8/16/2014)... have found a way to make atomic-force microscope probes ... as small as the weight of an individual virus. ... National University (ANU), hinges on using laser beams to ... , "The level of sensitivity achieved after cooling is ... a large virus that is 100 billion times lighter ...
(Date:8/15/2014)...   Hospira, Inc. (NYSE: HSP ... infusion technologies, today announced that the company will present ... Sept. 9, 2014, in New York ... at 11:45 a.m. Eastern time on Tuesday, Sept. 9, ... through a live audiocast accessible via the investor relations ...
Breaking Biology Technology:China – Land of Opportunities & Challenges for the Clinical Research Industry, New Webinar Hosted by Xtalks 2Scientific and Economic Consulting in Canada Industry Market Research Report Now Available from IBISWorld 2Scientific and Economic Consulting in Canada Industry Market Research Report Now Available from IBISWorld 3Laser makes microscopes way cooler 2
... Milwaukee, Wis. — A water main break Thursday ... disrupt water service Friday to 37 companies in the ... parks director of development said businesses in the incubator ... Mascari, whose office is located in the 137,000-square-foot Technology ...
... Madison, Wis. A professor who has worked for ... the lifespan of rhesus monkeys was featured in the MIT ... a colony of 78 monkeys at the University of Wisconsin-Madison, ... expand the lifespans of mice. But while testing on mice ...
... Third Wave Technologies said on Tuesday that a patent ... of its intellecual property in the U.S. , ,The patent ... analysis products with a type of chain reaction that makes ... Japanese patent for its existing Invader chemistry. , ,"These important, ...
Cached Biology Technology:
... (Dual-Stage Quadrupole) Thermo Scientific (Part of ... analytical instrumentation, introduces the latest product innovation ... Based on the proven reliability and performance ... systems, the DSQ II incorporates the new ...
... variant: With the macro- and ... and Skoog (1962) and the ... et al. (1968). Preparation Quantity ... grams of powder per liter ...
... Contents include: Microarray hybridization chamber ... chamber top, clamp, thumbscrew) Microarray chamber user ... and are intended to be cleaned and ... with Agilents Catalog Oligo Microarray kits and ...
Reported to support murine B lymphocytes, hematopoietic tissue from bone marrow, B cells stimulated with lipopolysaccharide, T lymphocytes, and a variety of hybrid cells....
Biology Products: