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Canada approves marijuana-based pain spray

with neuropathic pain for five years. “At times, putting on clothes or anything touching me can be too much to take,?he added.

Data demonstrates efficacy
While there is no complete cure for MS or neuropathic pain, a double-blind placebo controlled parallel group study demonstrated that Sativex provided significantly greater pain relief than placebo. Sativex also significantly reduced pain-related sleep disturbance.

Principal components
A product resulting from the pioneering research efforts of UK-based GW Pharmaceuticals plc and marketed in Canada by Bayer HealthCare, Pharmaceuticals Division, Sativex is the first product indicated in Canada as adjunctive treatment for the symptomatic relief of neuropathic pain in MS.

Its principal active cannabinoid components are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The ratio of THC to CBD in Sativex is 2.7 mg : 2.5 mg per spray, ensuring a standardized dose is delivered each time it is used.

“The approval of Sativex is good news for the Canadian MS community. People living with MS and neuropathic pain need new options to address their pain. Sativex will likely be welcomed by the many people with MS, whose quality of life has been further compromised with neuropathic pain,?said Dr. William J. McIlroy, National Medical Advisor, MS Society of Canada.

How Sativex works
Sativex is administered through a spray pump under the tongue or on the inside of the cheek, providing reliable, self-administered pain relief. The spray formulation allows for more flexible dosing than an oral tablet, well suited to the variable nature of neuropathic pain experienced by people with MS.

“Because Sativex is designed for self-administration, this allows for flexible dosing and puts the patient in control of their pain,?said Dr. Gordon. “This is very important since pain severity varies between different patients and even in the same patient at different times.?/p> <
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Source:GW Pharmaceuticals


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