Navigation Links
Can dogs smell cancer?

In a society where lung and breast cancers are leading causes of cancer death worldwide, early detection of the disease is highly desirable. In a new scientific study, researchers present astonishing new evidence that man's best friend, the dog, may have the capacity to contribute to the process of early cancer detection.

In this study which will be published in the March 2006 issue of the journal Integrative Cancer Therapies published by SAGE Publications, researchers reveal scientific evidence that a dog's extraordinary scenting ability can distinguish people with both early and late stage lung and breast cancers from healthy controls. The research, which was performed in California, was recently documented by the BBC in the United Kingdom, and is soon to be aired in the United States.

Other scientific studies have documented the abilities of dogs to identify chemicals that are diluted as low as parts per trillion. The clinical implications of canine olfaction first came to light in the case report of a dog alerting its owner to the presence of a melanoma by constantly sniffing the skin lesion. Subsequent studies published in major medical journals confirmed the ability of trained dogs to detect both melanomas and bladder cancers. The new study, led by Michael McCulloch of the Pine Street Foundation in San Anselmo, California, and Tadeusz Jezierski of the Polish Academy of Sciences, Institute of Genetics and Animal Breeding, is the first to test whether dogs can detect cancers only by sniffing the exhaled breath of cancer patients.

In this study, five household dogs were trained within a short 3-week period to detect lung or breast cancer by sniffing the breath of cancer participants. The trial itself was comprised of 86 cancer patients (55 with lung cancer and 31 with breast cancer) and a control sample of 83 healthy patients. All cancer patients had recently been diagnosed with cancer through biopsy-confirmed conventional methods such as a mammogram, or CAT scan and had not yet undergone any chemotherapy treatment. During the study, the dogs were presented with breath samples from the cancer patients and the controls, captured in a special tube. Dogs were trained to give a positive identification of a cancer patient by sitting or lying down directly in front of a test station containing a cancer patient sample, while ignoring control samples. Standard, humane methods of dog training employing food rewards and a clicker, as well as assessment of the dog's behavior by observers blinded to the identity of the cancer patient and control samples, were used in the experiment.

The results of the study showed that dogs can detect breast and lung cancer with sensitivity and specificity between 88% and 97%. The high accuracy persisted even after results were adjusted to take into account whether the lung cancer patients were currently smokers. Moreover, the study also confirmed that the trained dogs could even detect the early stages of lung cancer, as well as early breast cancer. The researchers concluded that breath analysis has the potential to provide a substantial reduction in the uncertainty currently seen in cancer diagnosis, once further work has been carried out to standardize and expand this methodology.


'"/>

Source:SAGE Publications


Related biology news :

1. Love at first smell
2. Bacteria feed on smelly breath (and feet)
3. Fighting malaria by manipulating mosquitoes sense of smell
4. New study examines how sense of smell affects mating and aggression in mice
5. Worms know bad food when they smell it
6. Duck-billed dino crests not linked to sense of smell
7. Neuroscientists discover new cell type that may help brain maintain memories of smells
8. Researchers show how brain decodes complex smells
9. Quick -- what’s that smell?
10. Contrary to common wisdom, scientist discovers some mammals can smell objects under water
11. When smell cells fail they call in stem cell reserves
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/15/2016)... -- A new partnership announced today will help life ... a fraction of the time it takes today, ... insurance policies to consumers without requiring inconvenient and ... rapid testing (A1C, Cotinine and HIV) and higi,s ... pulse, BMI, and activity data) available at local ...
(Date:3/31/2016)...   LegacyXChange, Inc. ... LegacyXChange is excited to release its first ... be launched online site for trading 100% guaranteed authentic ... also provide potential shareholders a sense of the value ... industry that is notorious for fraud. The video is ...
(Date:3/22/2016)... India , March 22, 2016 /PRNewswire/ ... market research report "Electronic Sensors Market for Consumer ... Proximity, & Others), Application (Communication & IT, ... Geography - Global Forecast to 2022", published ... industry is expected to reach USD 26.76 ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 A person commits a crime, and the ... track the criminal down. An outbreak of foodborne ... Administration (FDA) uses DNA evidence to track down the bacteria ... far-fetched? It,s not. The FDA has increasingly used a complex, ... foodborne illnesses. Put as simply as possible, whole genome sequencing ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... NEWPORT BEACH, Calif. , June 23, 2016 /PRNewswire/ ... offering new biological discoveries to the medical community, has ... and co-founder Matthew Nunez . "We ... provide us with the capital we need to meet ... funding will essentially provide us the runway to complete ...
(Date:6/23/2016)... ... June 23, 2016 , ... Velocity Products, a ... designed, tuned and optimized exclusively for Okuma CNC machining centers at The International ... a collaboration among several companies with expertise in toolholding, cutting tools, machining dynamics ...
Breaking Biology Technology: