Navigation Links
Caloric restriction won't dramatically extend life span in humans: UCLA research

consume the most calories have a shorter life span, and that if people severely restrict their calories over their lifetimes, their life span increases by between 3 percent and 7 percent -- far less than the 20-plus years some have hoped could be achieved by drastic caloric restriction. He considers the 3 percent figure more likely than the 7 percent.

"The trade-off between calories and longevity appears to be close to a linear relationship, but the slope isn't very steep," said Phelan, whose model predicts the relationship between calories consumed and life span.

Phelan's conclusion is that the few extra years of life are not worth the suffering necessary to achieve them.

"Do you want to spend decades severely limiting what you eat to live a few more years? You will be unhappy and then your life will end shortly after mine ends," Phelan jokes.

Scientists have known for six decades that cutting the caloric intake of rodents by 40 percent or 50 percent results in dramatically longer lives for them.

"You can practically double their life span," Phelan said. "The same result has been found in fish, spiders and many other species. If it works for them, some thought, it should work for us; I'm here to tell you it doesn't."

Phelan, co-author of the book, "Mean Genes," conducted his dissertation at Harvard University 10 years ago on caloric restriction and on why it works in extending the lives of rodents.

"When you restrict the caloric intake of rodents, the first thing they do is shut off their reproductive system," said Phelan, citing a finding from his dissertation. A normal rodent reaches maturity at one month of age, and begins reproducing its body weight in offspring every month and a half. If humans shut off reproduction by severely limiting calories, "our reduction in wear and tear on the body is minimal," he said.

The rodents placed on severely restricted diets bit people who tried to hold them, and
'"/>

Source:University of California - Los Angeles


Page: 1 2 3

Related biology news :

1. Air travel and flu: Post-9/11 restrictions delayed start of season
2. Better health twice as likely for nonsmokers who live and work with smoking restrictions
3. Learning to fight an adversary that wont stay down
4. Field tested: Grasslands wont help buffer climate change as carbon dioxide levels rise
5. Biodiesel wont drive down global warming
6. New miniaturised chip dramatically reduces time taken for DNA analysis
7. Hospitalizations because of chicken pox down dramatically since implementation of vaccine
8. Simple idea to dramatically improve dengue vaccinations
9. Lack of a key enzyme dramatically increases resistance to sepsis
10. Smoking ban dramatically reduces air pollution in Irish pubs
11. Growing nerve cells in 3-D dramatically affects gene expression
Post Your Comments:
(Date:3/17/2015)... , March 17, 2015 ... company specializing in clinical study management systems, is ... in attendance at ARENA,s Outsourcing in Clinical Trials ... This event provides an excellent forum for MedNet ... flexible and affordable software-as-a-service (SaaS) eClinical technology platform. ...
(Date:3/16/2015)... Between 16 and 20 ... innovations in biometric identification at the CeBIT exhibition ...      (Photo: http://photos.prnewswire.com/prnh/20150316/735333 ) , ... at the forefront: the company,s all new BiometricGate ... Germany . BiometricGate is the first ...
(Date:3/12/2015)... Beta Systems today announced ... management (IAM) solution for a fixed price and ... new IAM package, customers benefit from the 30 ... IAM implementations across different industries. The new fixed-price ... any necessary services and consulting. It spans the ...
Breaking Biology News(10 mins):Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2
... begin to get larger and what advantage did this increase ... of scientists examined the earliest communities of large multicellular organisms ... The life scientists used a novel application ... the scientific processes operating in the deep sea 580 million ...
... renowned for their extraordinary biotainspiring biologists and providing key ... of the devastating effects of human colonization, island ecosystems ... vital international concern. , Scientists are generating data ... now is an opportune time to bring together island ...
... microbial communities that reside in the human gut and their ... most exciting new areas of research today. To address the ... health-care professionals from all over the world will come together ... Florida, on March 8 and 9, 2014. The meeting is ...
Cached Biology News:Scientists reveal why life got big in the Earth's early oceans 2Island Biology 2014: An International Conference on Island Evolution, Ecology, and Conservation 2Attend the Gut Microbiota for Health World Summit 2014 2
(Date:3/27/2015)... WuXi PharmaTech (Cayman) Inc. (NYSE: ... technology platform company serving the global pharmaceutical, biotechnology, ... Investigational New Drug (IND) application for WuXi MedImmune,s ... been accepted for review by the China Food ... September 2012, MedImmune, the global biologics research and ...
(Date:3/26/2015)... /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") ... certain matters, including the appointment of auditors, its annual ... 2015 (the "Meeting") was adjourned, as previously disclosed on ... a.m. ( Toronto time). The date ... previous disclosed. The Meeting will reconvene at the offices ...
(Date:3/26/2015)... 2015 PAREXEL International Corporation (Nasdaq: ... research organization , announced today that the ... acquire all of the business assets of privately-owned ... of specialized pharmacovigilance services, based in Chandigarh, ... assessment, monitoring, and prevention of adverse effects ...
(Date:3/25/2015)... is one of the most attractive in the emerging ... a growing economy and increasing government investment in healthcare, ... Russian market is set to grow at twice the ... around 10-15% annually reaching an approximate market value of ... Green Cross provides total healthcare solutions that ...
Breaking Biology Technology:Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 2Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 3SQI Diagnostics Inc. Announces Adjournment of Meeting 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4
... By Julia Cino, PhD ... Introduction , ... to manipulate DNA to identify,excise, move and place genes into a variety ... use for many of these recombinant organisms is to produce,proteins. Since many ...
... , , ... Introduction , ... in a series documenting,simple protocols for culturing cells in a BioFlo ... of vessels, impellers,and control modules to enable growth of a wide variety,of ...
... , Microscale on-membrane PMF analysis ... the microdispensing function of a chemical printer (Refer to AXIMA Application ... with the chemical printer enables MS analysis with high mass accuracy ... E. coli separated by 2-dimensional electrophoresis were transferred to a PVDF ...
Cached Biology Technology:High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 2High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 3High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 4High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 5High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 6High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 7High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation 8Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 2Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 3Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 4Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 5Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 6Direct On-Membrane MS/MS Analysis using the Chemical Printer (CHIP-1000) and AXIMA-QIT 2
Mouse monoclonal [4i144] to HLA Class II DQ1 7 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 2 Antigen DQ1,7....
... omental preadipocytes are isolated ... healthy donors. There is ... cells. Please inquire for ... also available. Academic discounts ...
Anti-ADAM-12 (Meltrin Alpha); carboxy terminal end; rabbit host...
...
Biology Products: