Navigation Links
Buying Time Through Hibernation on Demand

reating severe blood-loss injury, hypothermia, malignant fever, cardiac arrest and stroke.

The potential medical benefits also include improving cancer treatment by allowing patients to tolerate higher radiation doses without damaging healthy tissue. Cancer cells, Roth explained, aren't dependent on oxygen to grow. As a result, they are more resistant to radiation than surrounding healthy cells, which need oxygen to live. Roth hypothesizes that temporarily eliminating oxygen dependence in healthy cells could make them a less-vulnerable target for radiation and chemotherapy and thus spare normal tissue during high-dose cancer therapy.

"Right now in most forms of cancer treatment we're killing off the normal cells long before we're killing off the tumor cells. By inducing metabolic hibernation in healthy tissue we'd at least level the playing field," he said. The delivery of such treatment could be as simple as an intravenous infusion of saline solution mixed with trace amounts of an agent that would interfere with the body's ability to use oxygen, Roth said.

Using oxygen deprivation to depress metabolic activity also might extend the amount of time that organs and tissues could be preserved outside the body prior to transplantation, Roth said. Yet another potential application of oxygen deprivation would include accelerating wound healing in patients, such as diabetics, whose ability to do so is compromised. This could reduce the number of amputations caused by irreparable tissue damage from wounds that won't heal. A wound to the skin allows the entry of oxygen, which initiates cell death. In healthy people, cell death subsides when a clot forms, which allows the healing process to begin. Exposing a diabetic's clot-resistant wound to an oxygen-free environment would speed the healing process.

While the notion of putting a human or a human organ into an oxygen-free state of biological limbo and then reversing the process at will with no
'"/>

Source:FHCRC


Page: 1 2 3 4 5

Related biology news :

1. High-Throughput GoMiner
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Buying Time Through Hibernation Demand

(Date:4/13/2015)... , April 13, 2015  higi, a leading cloud-based ... to more fully engage with their communities around health ... privacy protected and secure API.  ... the most accessible, affordable, and convenient vehicle to receive ... The API will allow higi,s ...
(Date:4/8/2015)... April 8, 2015  Infinisource, a leading provider ... and Morpho, a leading supplier of biometric identification ... the market,s most advanced biometrically-enabled time clock, the ... time clock is setting a bold, new standard ... for the small and mid-size employer. When connected ...
(Date:4/2/2015)... , April 2, 2015 At its ... Salt Lake City , the American College of ... five new directors to its Board.  Members of the ... ACMG and for forming and advancing its policies and ... genetics profession. "It,s an eventful time in ...
Breaking Biology News(10 mins):higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
... is often considered to be a problem of towns and cities ... BMC Public Health shows that binge drinking in rural ... Carolin Donath, from the Psychiatric University Clinic Erlangen, looked at the ... Germany and found that more than 93% of the young people ...
... A team of researchers, led by University of ... molecular mechanism implicated in geographic atrophy, the major ... Their article, "DICER1 Deficit Induces Alu ... online by the journal Nature on ...
... illicit drugs, shampoo, toothpaste, pesticides, chemical run-off from ... aquifer under Mexico,s "Riviera Maya," research shows. ... caves under the popular tourist destination on the ... the caves and into the Caribbean Sea. ...
Cached Biology News:Pivotal discoveries in age-related macular degeneration 2Pollutants in aquifers may threaten future of Mexico's fast-growing 'Riviera Maya' 2Pollutants in aquifers may threaten future of Mexico's fast-growing 'Riviera Maya' 3
(Date:4/24/2015)... 24 , 2015 PAREXEL International Corporation ... provider, today announced that Partnerships in Clinical Trials named ... the 2015 Clinical Innovator of the Year.  The honor ... for the Company,s Perceptive MyTrials ® Data-Driven Monitoring ... night during the 2015 Partnership Awards in ...
(Date:4/23/2015)... April 23, 2015 The Thomas ... to conduct a groundbreaking pilot study to see ... reversed in as little as three to six ... metabolic and nutritional medicine—will aggressively target and simultaneously ... destroy our aging brain. These include oxidative stress, ...
(Date:4/23/2015)... DIEGO , April 23, 2015  Neurocrine Biosciences, ... Company will report its first quarter 2015 results before ... Neurocrine will then host a live conference call and webcast ... update Thursday morning, April 30, 2015 at 8:00 a.m. ... can access the live conference call by dialing 866-952-1906 ...
(Date:4/23/2015)... April 23, 2015  Veracyte, Inc. (NASDAQ: VCYT ) ... agreement to sell approximately $40 million of its common ... investors will purchase an aggregate of 4,907,975 shares of ... share, the closing stock price on April 22, 2015. ... investors, including Broadfin Capital, Camber Capital, Deerfield, Longwood Capital ...
Breaking Biology Technology:PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 2PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 3PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 4PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 5New Study Looks to Reverse Alzheimer’s Disease 2New Study Looks to Reverse Alzheimer’s Disease 3Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Veracyte, Inc. Announces $40 Million Private Placement 2Veracyte, Inc. Announces $40 Million Private Placement 3Veracyte, Inc. Announces $40 Million Private Placement 4
... CENTENNIAL, Colo., July 28, 2011 AllograftPossibilities.org ... for straightforward information on tissue donation and transplant on ... life-enhancing benefits of organ donation, tissue donation is still ... AlloSource , a leading developer, processor, and distributor of ...
... (NASDAQ: VRNM ), a pioneer in the ... announced that it repurchased approximately $5.2 million in principal ... in principal amount of 9% Notes.   ... step toward creating a capital structure that is appropriate ...
... Purdue University researchers is among a small group in ... captures new states of matter and could have applications ... is used to observe states in which electrons no ... are governed by their mutual interactions. Michael Manfra, ...
Cached Biology Technology:AllograftPossibilities.org Meets Unmet Need for Consumer-Oriented Information on Tissue Donation, Transplantation on the Internet 2AllograftPossibilities.org Meets Unmet Need for Consumer-Oriented Information on Tissue Donation, Transplantation on the Internet 3Verenium Announces Debt Repurchase 2Verenium Announces Debt Repurchase 3Material created at Purdue lets electrons 'dance' and form new state 2Material created at Purdue lets electrons 'dance' and form new state 3
... The c-Jun proto-oncogene was first identified as ... v-jun oncogene. Jun B and Jun D have ... in their C-terminal regions, which are involved in ... which are involved in transcriptional activation, diverge. ...
...
... Rabbit polyclonal to JAK2 (phospho ... tested applications). Antigen: ... JAK2 around the phosphorylation site of ... Entrez Gene ID: ...
... Buffer, used in conjunction with eBioscience ... be used to fix and permeabilize ... of cytokines and other cytoplasmic and/or ... specially formulated for reducing non-specific staining ...
Biology Products: