Navigation Links
Breast tumors in mice eradicated using cancer vaccine

t on the idea of using Listeria as a cancer vaccine vector over ten years ago. "It took a while to dissect what elements of an immune response were best able to cause the rejection of established tumors," she says. "But in the last couple of years it has paid off and we are very excited to see the technology finally being tested in cancer patients. The dream of the cancer immunotherapist is to provide an alternative and more humane way of controlling metastatic disease than current chemotherapies."

The Listeria vector is currently being prepared for a clinical trial targeting a tumor antigen associated with cervical cancer by Advaxis Inc., a cancer vaccine biotech company that has licensed Penn patents on the use of Listeria monocytogenes as a vaccine vector. Paterson is the scientific founder of Advaxis and Chair of the Scientific Advisory Board. The successful demonstration that the Listeria vector technology can also be used with the HER-2/neu molecule paves the way for applying this promising cancer vaccine approach to breast cancer.

This research was funded by the Department of Defense and the National Cancer Institute. Co-authors are Reshma Singh and Mary E. Dominiecki, both from Penn, as well as Elizabeth M. Jaffee from the Johns Hopkins University School of Medicine. This release and related images can also be found at: www.uphs.upenn.edu/news.


'"/>

Source:University of Pennsylvania School of Medicine


Page: 1 2 3

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
3. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
4. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
5. New Breast Cancer Test Could Save Lives
6. Breast Cancer May Be Uniquely Sensitive To Inhibitors Of PI3K Pathway
7. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
8. Nanoparticle Breast Cancer Drug Approved by FDA
9. Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer
10. Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer
11. Affymetrix and bioMerieux Extend Their Agreement on GeneChip(R) Technology to Breast Cancer Diagnostics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Breast tumors mice eradicated using cancer vaccine

(Date:4/27/2015)... , April 27, 2015  For more than four ... show has been the premier worldwide event for the ... is a must-attend event for any local, national, or ... the emerging commercial markets and current applications of unmanned ... of this projected $48 billion industry, and how it ...
(Date:4/27/2015)... , Apr. 27, 2015 Profile Solutions, ... control and security systems is pleased to announce that ... as a consultant and member of its scientific advisory ... widely known as a thought leader in technology-enhanced learning ... Technology Group, and has published studies and books focused ...
(Date:4/20/2015)... 2015 Huntington Memorial Hospital is the first ... new miniaturized, wireless monitoring sensor to manage heart failure ... only FDA-approved heart failure monitoring device that has been ... physicians to manage heart failure. The CardioMEMS ... the pulmonary artery (PA) during a non-surgical procedure to ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3
... Jan. 24, 2011 More than a dozen University ... from robot-assisted surgery techniques to improving heart and breast ... computational surgery Jan. 26-28. The symposium will be held ... Held at the Methodist Institute for ...
... will host its 2011 Biodefense and Emerging Diseases Research ... Hotel in Washington, DC. The purpose of this ... out research to defend against the threat of bioterrorism ... recognizing that emerging infectious diseases serve as a paradigm ...
... important in any relationship, but for spiders, it can be ... male spider needs to convince potentially cannibalistic females that he ... research from the University of Cincinnati shows that male wolf ... increasing their opportunities to successfully mate. To improve the ...
Cached Biology News:Forum to focus on using robotics, imaging and simulation in surgeries 2Forum to focus on using robotics, imaging and simulation in surgeries 3Spiders adjust courtship signals for maximum effect 2Spiders adjust courtship signals for maximum effect 3
(Date:5/5/2015)... , May 5, 2015  Renova™ Therapeutics, ... congestive heart failure and other chronic diseases, has ... independent analysis designed to reflect the healthcare patterns ... This model will be used to characterize the ... could have on those groups of patients and ...
(Date:5/5/2015)... YORK , May 5, 2015 ... announced that Andrew Gengos , President and Chief ... May 7, 2015. DATE:  Thursday, May 7, ... LINK:  http://VirtualInvestorConferences.com > click the red ... be a live, interactive online event where investors ...
(Date:5/5/2015)... D.C., USA (PRWEB) May 05, 2015 ... regulations covering a wide range of key photonics technologies ... hampering global competitiveness of U.S. industry. To help the ... webinar on 12 May on the proposed changes ... the commodities covered by International Traffic in Arms Regulations ...
(Date:5/5/2015)... 2015 Research and Markets ( ... "Clinical Laboratory, Molecular Diagnostics and Genomic Testing ... - Global Version" report to their offering. ... area of molecular diagnostics and pharmacogenics hold the ... market that is moving out of the national ...
Breaking Biology Technology:RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 2RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 3ImmunoCellular Therapeutics to Webcast Live at VirtualInvestorConferences.com on May 7 2Comments needed now from photonics industry on revisions of U.S. export rules 2Comments needed now from photonics industry on revisions of U.S. export rules 3Comments needed now from photonics industry on revisions of U.S. export rules 4Global Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market Trends and Forecast 2015 to 2019 2
... , - Books Authored by ... Two of the biggest names in health care publishing, ... agreement to,co-publish International Classification of Diseases, Ninth Revision, Clinical,Modification (ICD-9-CM) ... Buck, beginning with the 2010 editions, in fall 2009. , ...
... Viroblock SA has announced,today that the first ... is active against human influenza. Viroblock,s patented,Cholesterol ... during the extra-cellular phase, by altering and ... The two pre-clinical studies exposed ferrets ...
... Md., March 31 ImQuest Life Sciences today ... of the pyrimidinedione small molecules as antiviral agents ... and Liver Disease meeting held last week in ... ten pyrimidinediones as inhibitors of HBV replication, with ...
Cached Biology Technology:The American Medical Association and Elsevier Join to Co-Publish ICD-9-CM and HCPCS Coding Reference Books 2The American Medical Association and Elsevier Join to Co-Publish ICD-9-CM and HCPCS Coding Reference Books 3Viroblock SA Reports Positive Results of Preclinical Studies in Antiviral Nasal Spray 2ImQuest Presents Data on the Anti-Hepatitis B Virus Activity of Pyrimidinediones at the 13th ISVHLD Meeting in Washington D.C. 2
Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, Monocyte Markers, Phosphatases & Regulators, Other Dendritic Cell Molecules...
MOUSE ANTI PORCINE SLA 1:FITC Immunogen: Porcine peripheral blood mononuclear cells....
NNT-1/BSF-3 (N-14)...
Monoclonal 8C2.1 is specific for Bunyavirus G1 as tested by neutralization, immunoprecipitation and immunobinding assays....
Biology Products: