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Breast stem cells have features similar to 'basal' tumors

d of research could in the long-term lead to the identification of new therapeutic targets against breast cancer, particularly the basal subtype." Currently drugs such as Tamoxifen, the aromatase inhibitors or Herceptin are ineffective against basal tumours and chemotherapy is the only option.

Dr Lindeman, who is also an oncologist at the Royal Melbourne Hospital, said that their team's findings will now be extended using excised human breast tissue andtumours. "We are fortunate that the Royal Melbourne Hospital campus is strongly committed to this type of translational research. Our hope is that this will lead to better cancer outcomes from a disease that strikes one in 11 Australian women."The team findings are published in the 19 July 2006 issue of the Journal of the National Cancer Institute.


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Source:Research Australia


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