Navigation Links
Breakthrough for stem cell research

A University of New South Wales (UNSW) researcher based at the Diabetes Transplant Unit (DTU) at Sydney's Prince of Wales Hospital has produced a human embryonic stem cell (hESC) line without the use of any animal products. The breakthrough eliminates the risk of animal-to-human contamination in potential stem cell therapy treatments.

"This is the first hESC line produced in Australia and only the second one in the world, which does not use animals in any way. Our line grows on human fetal fibroblast feeder layer that does not require fetal calf serum," said UNSW Senior Lecturer, Dr Kuldip Sidhu, who was the lead scientist responsible for the creation of the line.

"Other researchers have used animal tissue to keep the hESC alive in the petri dish or as a culture to grow it on," said Dr Sidhu. "Those animal products have the potential to transmit retroviruses in humans, which could have disastrous consequences."

Human embryonic stem cell lines are derived from specialized cells from embryos donated by infertile couples that specifically consented for their excess embryos to be used in stem cell research.

These lines could eventually lead to safer treatments for conditions such as diabetes, Parkinson's disease, spinal cord injury and even breast cancer.

"The new line, named 'Endeavour 1', is only the fifth human embryonic stem cell line to be produced in Australia," said UNSW Professor Bernie Tuch, Director of the DTU. "We now hope to collaborate with other researchers, using this line. We will also make it available to other researchers for their own work."

The National Health and Medical Research Council granted a licence to IVF Australia in collaboration with the DTU at the Prince of Wales Hospital to produce six stem cell lines in November 2004. Seed funding for the project came initially from the Australian Foundation for Diabetes Research, and subsequently from Diabetes Australia.

"Couples who have completed their families often ask us to donate the excess embryos created during their past treatments to research to help others," said Emeritus Professor Doug Saunders, Chair of Research & Development Committee, IVF Australia. "We are very encouraged to see the progress of this significant research project."


'"/>

Source:University of New South Wales


Related biology news :

1. Breakthrough Microarray-based Technology for the Study of Cancer
2. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
3. Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications
4. Breakthrough isolating embryo-quality stem cells from blood
5. Breakthrough System for Understanding Ocean Plant Life Announced
6. Breakthrough: Scientists create worlds tiniest organic particles
7. Breakthrough in micro-device fabrication combines biology and synthetic chemistry
8. Sciences Breakthrough of the Year: Watching evolution in action
9. Breakthrough in understanding type-2 diabetes as key genes identified
10. Breakthrough vaccine to treat chemo-resistant ovarian cancer
11. HIV vaccine trial breaks ground for future research
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... Research and Markets has announced the addition ... to their offering. The report ... to grow at a CAGR of 12.28% during the period 2016-2020. ... in-depth market analysis with inputs from industry experts. The report covers ... The report also includes a discussion of the key vendors operating ...
(Date:6/22/2016)... American College of Medical Genetics and Genomics was once again ... of the fastest-growing trade shows during the Fastest 50 Awards ... Las Vegas . Winners are ... of the following categories: net square feet of paid exhibit ... 2015 ACMG Annual Meeting was ranked 23 out of 50 ...
(Date:6/22/2016)... June 22, 2016   Acuant , ... verification solutions, has partnered with RightCrowd ® ... for Visitor Management, Self-Service Kiosks and Continuous ... that add functional enhancements to existing physical ... and venues with an automated ID verification ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... Lemonade Stand Foundation (ALSF), a leading national childhood cancer ... bioinformatics lab, using ,big data, to advance the pace ... Liz Scott , co-executive director of ALSF and Alex,s ... Washington, D.C. , hosted by Vice President ... pediatric cancer research and awareness. The ...
(Date:6/27/2016)... -- Global demand for enzymes is forecast to grow ... billion.  This market includes enzymes used in industrial ... animal feed, and other markets) and specialty applications ... beverages will remain the largest market for enzymes, ... containing enzymes in developing regions.  These and other ...
(Date:6/27/2016)... 2016 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the ... major shareholders, Clean Technology Fund I, LP and Clean ... based venture capital funds which together hold approximately ... fully diluted, as converted basis), that they have entered ... equity holdings in Biorem to TUS Holdings Co. Ltd. ...
(Date:6/27/2016)...  Sequenom, Inc. (NASDAQ: SQNM ), a ... the development of innovative products and services, announced today ... States denied its petition to review decisions ... U.S. Patent No. 6,258,540 (",540 Patent") are not patent ... Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories decision.  ...
Breaking Biology Technology: