Navigation Links
Breakthrough developments in rheumatoid arthritis reported

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life – the human genome – to figure out what makes these people susceptible to the disabling inflammatory condition.

Dr. Gregersen has finally closed the circle between key genes identified in his laboratory at the Robert S. Boas Center for Genomics and Human Genetics at The Feinstein Institute for Medical Research in Manhasset, NY and more than a 1,000 patients with rheumatoid arthritis. The genes will help tell the story of how the immune system works to create specific antibodies that in turn increase a person’s risk for this crippling disease.

On Monday at the Federation of Clinical Immunology Services’ (FOCIS) meetings in San Diego, CA, Dr. Gregersen and his colleagues will be presenting the lab’s latest genetic findings. The group conducted genome-wide scans to identify polymorphisms, or genetic variants, that are associated with the inflammatory condition and can be used to understand the triggers of the disease. This will provide key insights into the pathways underlying rheumatoid arthritis and other autoimmune diseases. It may ultimately provide tests to predict who will respond to the available new treatments. Franak Batliwalla, PhD, also of The Feinstein Institute, will be presenting related studies on biomarkers and genetic influences on drug response at the same meeting.

Identifying Immune System Mediators

About one percent of the US population will develop rheumatoid arthritis, an autoimmune disease that leads to painful joint swelling. Scientists are cracking the genetic code that makes the immune system wage an attack on a person’s joints. Over the last decade, Dr. Gregersen and his colleagues have been amassing a genetic database complete with sibl
'"/>

Source:North Shore-Long Island Jewish (LIJ) Health System


Page: 1 2 3 4

Related biology news :

1. Breakthrough Microarray-based Technology for the Study of Cancer
2. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
3. Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications
4. Breakthrough isolating embryo-quality stem cells from blood
5. Breakthrough System for Understanding Ocean Plant Life Announced
6. Breakthrough: Scientists create worlds tiniest organic particles
7. Breakthrough in micro-device fabrication combines biology and synthetic chemistry
8. Sciences Breakthrough of the Year: Watching evolution in action
9. Breakthrough for stem cell research
10. Breakthrough in understanding type-2 diabetes as key genes identified
11. Breakthrough vaccine to treat chemo-resistant ovarian cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Breakthrough developments rheumatoid arthritis reported

(Date:3/19/2015)... 19, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... the growing mobile commerce market, announces its biometric payment technology, ... that aired this week on Washington DC,s ... In a segment "The Next Great Thing", host Laura ... to pay, and ,a really big breakthrough in mobile payment.,  ...
(Date:3/17/2015)... MedNet Solutions , a global ... management systems, is pleased to announce that company ... in Clinical Trials Southeast conference – March 24-25 ... forum for MedNet to showcase iMedNet , ... eClinical technology platform. We strongly encourage ...
(Date:3/17/2015)... , March 17, 2015  MecklerMedia Corporation ... largest exhibition for service robots ever held in ... takes place on May 11-13, 2015 at the ... exhibitors for the event include: Acorn Product Development; ... EZ-Robot; Infranor; Kinova Robotics; Littler; NewBotic Corporation; Neya ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2
... EDITOR,S PICK: SIRT(ain) benefit of reducing calories ... is reaching epidemic proportions. One of the main risk ... cells in the body (particularly liver, fat, and skeletal ... Substantially reducing caloric intake enhances the sensitivity of skeletal ...
... (MGH) researchers along with collaborators from Massachusetts ... have found a way to block, in an ... many disease conditions. In their report receiving ... the investigators describe using small interfering RNA technology ...
... in our body have a system that can handle ... underlying mechanism is called autophagy and literally means "self-eating". ... system and the increased release of building blocks equip ... render them resistant towards treatment. "We have ...
Cached Biology News:JCI online early table of contents: Oct. 10, 2011 2JCI online early table of contents: Oct. 10, 2011 3JCI online early table of contents: Oct. 10, 2011 4JCI online early table of contents: Oct. 10, 2011 5JCI online early table of contents: Oct. 10, 2011 6Novel technique uses RNA interference to block inflammation 2Small molecules can starve cancer cells 2
(Date:4/20/2015)... Sinovac Biotech Ltd. (Nasdaq: SVA), a leading provider of ... results for the fourth quarter and full year ended ... Highlights(Compared to the fourth quarter 2013) , Quarterly ... from $22.9 million in the prior year period. Excluding ... vaccine of $0.1 million in the fourth quarter of ...
(Date:4/18/2015)... Aurigene and its partner ... presenting data at the poster sessions from two ... Annual Meeting (April 18-22 in Philadelphia, ... http://photos.prnewswire.com/prnh/20130418/608115 ) , Aurigene will present ... molecule inhibitors program, which is currently in preclinical ...
(Date:4/17/2015)... , April 17, 2015 /PRNewswire/ - SQI Diagnostics ... and diagnostics company that develops and commercializes proprietary ... today announced that it has received approval from ... of 5,126,044 outstanding common share purchase warrants ("the ... connection with the Company,s May 2013 private placement ...
(Date:4/17/2015)... Houston, TX (PRWEB) April 17, 2015 ... genomics and proteomics technologies, announced today that it ... sequencing system, an innovative multiplex PCR based targeted ... ultra-high resolution sequence analysis, that enables accurate detection ... pending Relay-PCR™ and Omega-Primer™ technologies. The company will ...
Breaking Biology Technology:Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 2Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 3Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 4Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 5Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 6Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 7Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 8Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 9Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 10Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 11Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 12Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 13Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 14Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 15Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 16Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 17Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 18Aurigene to Present its NAMPT and IRAK-4 Inhibitors Programs at AACR 2015 2SQI Diagnostics to Extend Warrant Expiry 2SQI Diagnostics to Extend Warrant Expiry 3LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 2LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 3
... , SPRINGFIELD, Ill., Dec. 1 ... that it was recently awarded two statuettes at the first-ever ... City. The CLIO Healthcare Awards recognizes creative excellence and innovation ... the CLIO Awards, one of the world,s most recognized awards ...
... ... Dynamics SL clients (including project accounting clients) to Synergy Business Solutions to maintain quality ... Seattle, ... the Microsoft Dynamics SL practice of Congruent Software, a Bellevue, WA business technology provider. ...
... , INDIANAPOLIS and NORTH VANCOUVER, British Columbia, Dec. ... The Dow Chemical Company (NYSE: DOW ), and ... and commercial license option agreement. The agreement provides Dow AgroSciences ... on an exclusive basis in major food crops, and on ...
Cached Biology Technology:Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 3Dow AgroSciences, Agrisoma Biosciences Announce Research and Commercial License Option Agreement for Agricultural Crops 2Dow AgroSciences, Agrisoma Biosciences Announce Research and Commercial License Option Agreement for Agricultural Crops 3
RAT ANTI RAT RT1Au (CLASS I POLYMORPHIC) Immunogen: AO lymphoid cells...
MOUSE ANTI HUMAN C-MYC aa171-188...
RABBIT ANTI NEOPTERIN...
... • Beagle serum is collected from fasted Beagle ... age Available Anticoagulants: N-02: ... K2EDTA N-08: Potassium Oxalate ... N-05: ACD N-07: CPD ...
Biology Products: