Navigation Links
Brain holds clues to bipolar disorder

Looking into the brain is yielding vital clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented today at the Seventh International Conference on Bipolar Disorder. Two studies, featured in a press briefing held at 12:15 p.m., Thursday, June 7, have helped to identify novel pathways and markers for diagnosis and treatment of the disease.

The first study, presented by Husseini K. Manji, M.D., chief of the Laboratory of Molecular Pathophysiology at the National Institute of Mental Health (NIMH), suggests that bipolar disorder arises from abnormalities in neuronal plasticity cascades – the complex machinery inside of nerve cells that regulates numerous processes inside the body. Using animal and cellular models, Dr. Manji and colleagues at NIMH showed that disruptions in these pathways resulted in many of the core symptoms of bipolar disorder and explained many other observations about the disease. The findings suggest a new avenue for treating the underlying cause of bipolar, rather than treating flare-ups of depression or mania, and also provide new targets, for improved medications many of which are being tested in clinical trials.

Mary Phillips, M.D., professor of psychiatry at the University of Pittsburgh School of Medicine and director of functional neuroimaging in emotional disorders at Western Psychiatric Institute and Clinic of UPMC, will discuss the emerging role of brain imaging techniques in psychiatry in general as well as in bipolar disorder. Using neuroimaging, Dr. Phillips has identified patterns of abnormalities in the neural systems that underlie emotional processing and cognitive control unique to the bipolar brain. Such abnormalities are valuable biomarkers for the illness and have the potential to help clinicians diagnose bipolar disorder earlier and more efficiently. Dr. Phillips also will present data illustrating how imaging can be used to identify biomarkers and how these marker
'"/>

Source:University of Pittsburgh Medical Center


Page: 1 2

Related biology news :

1. Drug That Tags Decision-making Areas Of The Brain May Aid
2. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
3. Transport System Smuggles Medicines Into Brain
4. Bird Brains Show How Trial and Error May Contribute to Learning
5. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
6. Wiley announces publication of Databasing the Brain
7. Scientists Propose Sweeping Changes to Naming of Bird Neurosystems to Acknowledge Their True Brainpower
8. Brain-mapping technique aids understanding of sleep, wakefulness
9. Some Brain Cells Change Channels To Fine-tune The Message
10. Brain Scans Reveal How Gene May Boost Schizophrenia Risk
11. Brain-injury rehabilitation depends on acetylcholine circuitry
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Brain holds clues bipolar disorder

(Date:7/23/2008)...LLAS July 24, 2008 One of the reasons people on ...y reduce their intake of fructose, a type of sugar... to a researcher at UT Southwestern Medical Center...f clinical nutrition and lead author of a study ap...ition , said her team,s findings suggest that the ...
(Date:7/23/2008)..., Ohio A recent study shows that popular fish oil... of small, acute wounds in human skin. But whether...lly suspected, remains a mystery. , The omega-3 ...ed to benefit cardiovascular health and other dise...eir anti-inflammatory properties. But insufficient...
(Date:7/23/2008)...ersity of Washington study of top-selling laundry ...tted dozens of different chemicals. All six produc... as toxic or hazardous under federal laws, but non...els. , "I first got interested in this topic beca... in public restrooms and the scent from laundry pr...
(Date:7/23/2008)...ts at Durham University (UK) are working on new wa...in the fight against global warming. , The Unive...up, which will be led by the newly-created positio... and Energy. , Researchers aim to find efficient...fuel fired power plants and storing it in former o...
Breaking Biology News(10 mins):Limiting fructose may boost weight loss, UT Southwestern researcher reports 2Limiting fructose may boost weight loss, UT Southwestern researcher reports 3Scientists suspect omega-3 fatty acids could slow acute wound healing 2Scientists suspect omega-3 fatty acids could slow acute wound healing 3Scientists suspect omega-3 fatty acids could slow acute wound healing 4Toxic chemicals found in common scented laundry products, air fresheners 2Toxic chemicals found in common scented laundry products, air fresheners 3Durham scientists to tackle CO2 storage in global warming challenge 2Fact Sheet Explains Cleaners Disinfectants 4778 1Breastfeeding Does Not Create Sagging Breasts 3B Study Throws Out Old Wives Tale 4776 1Breastfeeding Does Not Create Sagging Breasts 3B Study Throws Out Old Wives Tale 4776 2Vaginal reconstruction not needed for most inter sex females Hopkins study shows 996 1Healthcare Workers to St Joseph Health System 3A Fair Election Agreement Now 4774 1Healthcare Workers to St Joseph Health System 3A Fair Election Agreement Now 4774 2
...t and least studied freshwater turtles has been fo... the threatened species can be saved from extincti...CI), World Wildlife Fund (WWF), the Cambodian Fish...servation Team captured and released an 11-kilogr...rtle (Pelochelys cantorii) during a survey in Marc...
...lain the brute strength of the tyrannosaurid, says...demonstrates how a fused nasal bone helped turn th...d, arch-like nasal bones are a unique feature of t...oral research fellow at the University of Alberta..... rexes from breaking their own skull while breaki...
...people in the European Union and a million in the ...defects of some part of their bone structure. Oper...itigate the damage, depend decisively on the mater...by INASMET-Tecnalia with the help of others, is wo...e. Seven other bodies, leaders in innovation withi...
...&D, a Korean research team led by Dr. Kyong-Ta...production is coordinated with the body,s natural ...ed by the pineal gland in the brain, which helps t...ly-24-hour cycle around which basic physiological ... is inhibited by light and enhanced by darkness, u...
Other Biology News:Rare soft-shell turtle, nesting ground found in Cambodia 2Rare soft-shell turtle, nesting ground found in Cambodia 3Fused nasal bones helped tyrannosaurids dismember prey 2Intelligent materials to regenerate bone tissue 2
(Date:7/24/2008)...re/ -- The Global Probiotics Council,(GPC), a comm...ult Honsha,Co., Ltd., announced the two awardees w...rant for Probiotics Research (YIGPRO) today. The p...who will continue to contribute to,the advancement...United,States., Ajay S. Gulati, MD, an Assistant ...
(Date:7/24/2008)... Important Advance in Radiofrequency ...if., July 24 /- PEAK Surgical, Inc., ...tissue dissection system,based on a proprietary te...rug Administration has granted the company 510(k) ... use in general surgery. The PEAK Surgery System,c...
(Date:7/24/2008)...ire/ -- Sagent Pharmaceuticals, Inc.,a privately-...nced that it,has launched ceftazidime for injectio...m antibiotic. Sagent will offer ceftazidime in 1,a...ge vials. According to,IMS data, 2007 sales of inj...ximately $45.7 million., "Sagent is proud to be p...
(Date:7/24/2008)...swire-FirstCall/ -- United,Therapeutics Corporatio...lease its 2008 second quarter financial results be...., United Therapeutics will host a half-hour tele.... Eastern Time. The teleconference is accessible,b...rs dialing,1-706-679-8129. A rebroadcast of the te...
Breaking Biology Technology:Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 2Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 3Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 4PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 2PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 3PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 4Sagent Pharmaceuticals Launches Ceftazidime for Injection, USP 2
...Your business card reads project manager. You just...to training, regularly participate in seminars and...osmosis). The methodology on your desk is almost w...s. Ill bet you could recite the cost control secti...g your walls than new paint. Youve managed countle...
...onference got off to a dynamic start on Tuesday mo...least a hundred entrepreneurs and industry represe... a success. The entrepreneurial boot camp was des...s, by providing a loose outline for success from a...is to focus on what were doing here, said Ken Wane...
...ng security solution that combines networking infr...olistic and efficient approach to security. It is ...ed networks. , ,Most security imperatives from an ...s, intrusion detection and a host of similar compo... an increased focus on both physical and network s...
...at homes and businesses are still as secure as the...rn professor James Carlini in an update about hack... service with more ease than ever before. , , War...ialing down a sequence of many phone numbers in a ...nd a weakness or an opening into a computer networ...
Other Biology Technology:Part 5 Project Performance Get on the path to continuous improvement 2Part 5 Project Performance Get on the path to continuous improvement 3Part 5 Project Performance Get on the path to continuous improvement 4Entrepreneurs get crash course for building a successful company 2Entrepreneurs get crash course for building a successful company 3IP Surveillance - Another Piece of the Converged Network 2IP Surveillance - Another Piece of the Converged Network 3Wardrivers now exploiting your wireless service with ease 2Wardrivers now exploiting your wireless service with ease 3Wardrivers now exploiting your wireless service with ease 4
...ay Kits are ideal for studying or screening novel ...rescence polarization (FP) The homogenous assay ut...ligand binding domain of human progesterone recept...tagged progesterone ligand, Fluormone PL Green or ...
...Kit (Catalog number SCR004) is a specific and sens...l differentiation by the determination of AP activ...onoclonal antibodies TRA-2-49 (Catalog Number MAB4...permit the detection of Liver / Bone / Kidney isoz...
... to Fc regions of many mammalian immunoglobulins. ...ed as affinity adsorbents to purify immunoglobulin...rum, hybridoma ascites fluids, tissue culture supe...ts are also commonly used to capture immune comple...
Rabbit polyclonal to Shigella Immunogen: Mixture of S. boydii, S. flexneri & S. dysenteriae.
Biology Products: