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Both alcoholism and chronic smoking can damage the brain's prefrontal cortex

the total to $10.3 million, contingent on a successful first phase. Subcontractors sharing the grant are:

  • Ripple LLC ?a Salt Lake City company that makes devices to record nervous system data ?will get up to $1.28 million over two years and a total of $1.94 million over four years. The company, founded by former U bioengineering graduate student Shane Guillory, will make the belt-pack computer and electronics to translate signals from the nervous system and wireless electrode array to the prosthetic arm and back again.

  • Fraunhofer IZM (Institute for Reliability and Microintegration) ?a branch of the German nonprofit contract research organization Fraunhofer-Gesellschaft ?will get up to $209,972 over two years and a total of $566,724 over four years. Fraunhofer IZM will help develop a system to supply electrical power wirelessly to the electrode array. It also will combine the electrode array with signal processors and amplifiers so that the implanted device ?less than one-third inch on a side ?can relay signals back and forth wirelessly between the remnant limb, the computer and artificial arm. This work falls under a new cooperative agreement between the University of Utah and Fraunhofer IZM.

  • Fraunhofer IBMT (Institute for Biomedical Technology), another branch of Fraunhofer-Gesellschaft, will receive up to $291,400 over two years and a total of $534,350 over four years. Fraunhofer IBMT will be responsible for putting the electrode array and related electronics inside a leak-proof coating so it is safe to implant in people.

As principal investigator for the Utah part of the prosthetic arm program, Clark will oversee the project. He also will participate particularly in preclinical and human studies of the interface device with hand-and-arm surgeon Douglas T. Hutchinson, an associate professor of orthopaedics, and Nicholas Brown, a research assistant professor in orthopaedic surgery.

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Source:Alcoholism: Clinical & Experimental Research


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