Navigation Links
Boosting HIV screening can increase survival and is cost effective

Expanded HIV screening can increase patient life span, prevent the spread of the disease, and is cost effective, researchers at Yale, Harvard and the Massachusetts General Hospital report in the February 10 issue of the New England Journal of Medicine (NEJM).

The study's findings are part of a two-paper series in NEJM on the value of expanded HIV screening in the United States. The Yale/Harvard study used different data and methods than another study by VA, Duke and Stanford researchers, yet both teams reached roughly the same conclusions.

"The publication of these papers represents a golden opportunity to jump-start the expansion of HIV testing services in the U.S.," said Yale lead author A. David Paltiel, associate professor of health and policy administration in the Department of Epidemiology and Public Health at Yale School of Medicine. "Our findings, coupled with those of our colleagues, firmly establish the great value of expanded screening."

Paltiel and his team developed a mathematical model of HIV screening and treatment to predict the costs and benefits of HIV counseling, testing and referral. They found that routine, voluntary HIV screening every three to five years is cost-effective by U.S. standards, in all but the lowest-risk populations. Frequent HIV screening in moderate-to-high-risk populations could produce life expectancy gains at costs that compare favorably to many commonly employed screening interventions in other chronic conditions, including breast cancer, colorectal cancer, diabetes and hypertension. Paltiel said that even in settings with HIV infection levels similar to the U.S. general population, one-time screening could deliver excellent return on investment.

"HIV is a severe disease that, left untreated, produces substantial morbidity and mortality," said Paltiel. "It has a long asymptomatic phase, which can be diagnosed using very effective, inexpensive tests. Most importantly, early detection speeds link age to proven, life-prolonging care and effective counseling to prevent further transmission."

Rochelle Walensky, assistant professor of medicine at Harvard and a co-author of the study, added, "The HIV epidemic is no longer confined to a handful of easily identifiable risk groups, yet current approaches to HIV testing are still focused on these sub-populations. The result is that 280,000 Americans with HIV remain unaware of their infection. Efforts to promote and finance routine, population-based HIV screening should be pursued aggressively."

Douglas K. Owens, M.D., of the VA Palo Alto Health Care System, and his team at the VA, Stanford and St. Michael's Hospital in Toronto, led another study in NEJM, which strongly supports Paltiel's findings. They developed a computer model to estimate the health benefits and expenditures of performing voluntary HIV screening programs in health care settings. They also found that screening for HIV infection is cost-effective relative to other commonly accepted screening programs and medical treatments.

Referring to the Yale/Harvard findings, Owens said, "It's exciting that a completely independent analysis had the same findings as we did. Both of these studies show that screening is life-prolonging and affordable."

The Yale/Harvard study was funded by the National Institute of Mental Health, the National Institute on Drug Abuse, the National Institute of Allergy and Infectious Diseases, and the United States Centers for Disease Control and Prevention.

Other authors on the study included Milton C. Weinstein and George R. Seage III of Harvard School of Public Health; Kenneth A. Freedberg of the Massachusetts General Hospital, Harvard School of Public Health and Boston University School of Public Health; April D. Kimmel and Hong Zhang of the Massachusetts General Hospital and Harvard Medical School; and Elena Losina of Boston University School of Public Health.


'"/>

Source:Yale University


Related biology news :

1. Boosting The BCG Vaccine To Beat Tuberculosis
2. Boosting newborns immune responses
3. Boosting brain power -- with chocolate
4. MetaChip provides quick, efficient toxicity screening of potential drugs
5. Researchers develop assay that could be applied to drug screening
6. NIH creates nationwide network of molecular libraries screening centers
7. UT Southwestern researchers develop screening test for cells that activate immune system
8. Newborn screening can cause unnecessary parental stress
9. Handling HPV vaccines and screening: The views of 100 authors
10. Hair-growth drug artificially lowers PSA levels in prostate cancer screening, study finds
11. Sexual cooperation: Mating increases longevity in ant queens
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... to expand at a CAGR of 25.76% during the ... is the primary factor for the growth of the ... https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global stem ... technology, application, and geography. The stem cell market of ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/30/2017)... HONG KONG , March 30, 2017 ... developed a system for three-dimensional (3D) fingerprint identification by adopting ground ... technology into a new realm of speed and accuracy for use ... applications at an affordable cost. ... ...
Breaking Biology News(10 mins):
(Date:8/17/2017)... (PRWEB) , ... August 17, 2017 , ... ... cancer research and personalized medicine, today announced the launch of a new breast ... Missouri. The study’s goal is to evaluate the potential for early detection of ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... and Electrospraying line of nanofiber and nanoparticle fabrication instruments ... the lab to fully automated pilot plants and equipment for industrial manufacturing. ...
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... While art ... are much more closely connected than one might think. A Mesh Is Also ... open at the University City Science Center’s Esther Klein Gallery (EKG) on August 17 ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... and Drug Administration (FDA) inspection at our Dilworth, MN site. The inspection took ... This inspection was conducted as part of a routine Bioresearch Monitoring Program (BIMO) ...
Breaking Biology Technology: