Navigation Links
Bones from blood: Scientists aim to break new ground on fractures

Scientists at the University of York have launched a new research project which aims to develop ways of making bones from blood.

Researchers from the University's Department of Biology are heading the EC-backed project to create bone structures from cord blood stem cells for use in the repair of bone defects and fractures.

The three-year ?.5 million research project involves scientists in the UK and across Europe, as well as academics from the University of York's Departments of Sociology and Philosophy, who will carry out sociological and ethical evaluations of the work. The project will seek to find a viable new medical use for the two million units of cord blood banked in Europe, and currently used for transfusions and treating leukaemia.

Biologist Dr Paul Genever, who is co-ordinating the project, said: "The mesenchymal stem cells (MSCs) in cord blood appear similar to bone marrow stem cells but they are hard to locate. We aim to isolate and expand them so we have enough cells to use in therapies.

"We also want to compare them with bone marrow and embryonic stem cells and investigate how we can turn them into bone structures for use as 3D bone replacements."

Dr Genever said if the creation of bone structures from stem cells proves viable, it might be used for cell-based therapies to repair bone defects and fractures. Ultimately, bone structures developed in this way could be used to make hip replacements more durable.

"The participation of colleagues from Sociology and Philosophy in a project such as this offers the opportunity for us to explore a more ethically and socially integrated kind of biology," he added.

Professor Andrew Webster and Dr Nik Brown, of the Science and Technology Studies Unit (SATSU) in the Department of Sociology, will link the scientific questions of MSC isolation and expansion to the wider environment and define potential barriers and areas of weakness in their use. They will conside r questions such as safety and standards, commercial viability, potential investment, consensus amongst scientists and clinical distribution.

Dr Stephen Holland and Professor Tom Baldwin, of the Department of Philosophy, will carry out an ethical evaluation of the research. This will include making sure that the project is conducted according to the highest standards of research governance. They will also investigate how the project contributes to the debate about the ethics of stem cell research. In particular, they will consider how potential benefits of these stem cell therapies can be weighed against ethical concerns."


'"/>

Source:University of York


Related biology news :

1. Bones hold the key to blood renewal
2. Bones at the nanoscale
3. Bones in motion: Brown scientists to create new 3-D X-ray system
4. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
5. Scientists Replicate Hepatitis C Virus in Laboratory
6. Scientists detect probable genetic cause of some Parkinsons disease cases
7. Scientists find missing enzyme for tuberculosis iron scavenging pathway
8. Scientists seek answers on what activates deadly anthrax spores
9. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
10. Scientists collaborate to assess health of global environment
11. Scientists decipher genome of fungus that can cause life-threatening infections
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... Research and Markets has announced the addition ... to their offering. The report ... to grow at a CAGR of 12.28% during the period 2016-2020. ... in-depth market analysis with inputs from industry experts. The report covers ... The report also includes a discussion of the key vendors operating ...
(Date:6/22/2016)... American College of Medical Genetics and Genomics was once again ... of the fastest-growing trade shows during the Fastest 50 Awards ... Las Vegas . Winners are ... of the following categories: net square feet of paid exhibit ... 2015 ACMG Annual Meeting was ranked 23 out of 50 ...
(Date:6/22/2016)... June 22, 2016   Acuant , ... verification solutions, has partnered with RightCrowd ® ... for Visitor Management, Self-Service Kiosks and Continuous ... that add functional enhancements to existing physical ... and venues with an automated ID verification ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...  Global demand for enzymes is forecast to ... $7.2 billion.  This market includes enzymes used in ... production, animal feed, and other markets) and specialty ... and beverages will remain the largest market for ... products containing enzymes in developing regions.  These and ...
(Date:6/27/2016)... ... , ... Parallel 6 , the leading software as a service (SaaS) ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication between ... Using the CONSULT module, patients and physicians can schedule a face to face virtual ...
(Date:6/27/2016)... , June 27, 2016   Ginkgo Bioworks , ... industrial engineering, was today awarded as one of ... of the world,s most innovative companies. Ginkgo Bioworks ... for the real world in the nutrition, health ... work directly with customers including Fortune 500 companies ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita ... miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject of ... now. , Diagnostic biomarkers are signposts in the blood, lung fluid or tissue ...
Breaking Biology Technology: