Navigation Links
Bone marrow stem cells may heal hearts even years after heart attacks

Left ventricular function and exercise capacity increased, while the area of heart muscle damage shrank, in 18 patients given infusions of their own bone marrow stem cells up to eight years after a heart attack, according to a new study in the Nov. 1, 2005, issue of the Journal of the American College of Cardiology.

"This new therapy is able to treat until now irreversible heart complaints and function disturbances in patients with chronic coronary artery disease after myocardial infarction, even many years after heart attack. Therefore there is hope for this large amount of patients with previous myocardial infarction and non-treatable complaints," said Bodo E. Strauer, M.D. from the Heinrich-Heine-University in D�sseldorf, Germany.

If further trials produce similar results, cardiac regeneration using stem cells could help to not only reverse some heart attack damage, reduce symptoms and improve the daily functioning of patients; it might also reduce the risk of heart failure, Dr. Strauer said.

Current heart attack interventions attempt to restore blood flow to the heart muscle as soon as possible, in order to limit the amount of permanent scarring. However, neither clotbusting drugs nor angioplasty can restore heart tissue that has already been damaged. Earlier studies demonstrated healing of heart muscle and improved heart function following injections of stem cells directly into the heart muscle or infusions of stem cells into key heart arteries soon after a heart attack.

This study is the first to report the results of stem cell infusions into the arteries of patients many months or years after a heart attack. The researchers harvested bone marrow from the hip bones of the patients, so there was no threat of transplant rejection. After processing, stem cells from the marrow were infused through a catheter into the coronary artery where the patient's heart attack occurred.

"The main results were at least threefold: an impro
'"/>

Source:American College of Cardiology


Page: 1 2 3 4

Related biology news :

1. Stem cells in bone marrow replenish mouse ovaries
2. Malfunctioning bone marrow cells sabotage nerve cells in diabetes
3. New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease
4. Bone marrow cells can become functional gut lining cells
5. Bone marrow may restore cells lost in vision diseases
6. Healing the heart with bone marrow cells
7. Leukemic cells find safe haven in bone marrow
8. Early-stage sperm cells created from human bone marrow
9. Wisconsin scientists grow critical nerve cells
10. Spleen may be source of versatile stem cells
11. Researchers discover way to make cells in the eye sensitive to light

Post Your Comments:
(Date:11/24/2009)... Springer and the American College of Medical Toxi...ate on the publication of the Journal of Medical ...T, beginning in March 2010. It was previously pub..., The Journal of Medical Toxicology , an interna...ancing the science and practice of medical toxicol...
(Date:11/24/2009)... This release is available in Spanish . , ...higher levels of inflammatory substances in the bl...ht; as shown by a research project of the Universi...o, a scientist at the School of Pharmacy. , The ... study in relation to the control of body weight a...
(Date:11/23/2009)..., A new study by the Wildlife Conservation Societ...arge swamp in the Republic of Congopart of the "mo...d last yearare becoming increasingly threatened by...udy recommends protection of the swamp forests adj...Reserve after recent surveys confirmed that high d...
Breaking Biology News(10 mins):Springer and the American College of Medical Toxicology to work together 2It can be predicted the reaction obese patients will have to a diet 2A year after discovery, Congo's 'mother lode' of gorillas remains vulnerable 2WuXi PharmaTech Announces Shareholder Resolutions Adopted at 2009 Annual General Meeting 13461 1WuXi PharmaTech Announces Shareholder Resolutions Adopted at 2009 Annual General Meeting 13461 2Research breakthrough will lead to more accurate weather forecasts 13460 1Research breakthrough will lead to more accurate weather forecasts 13460 2Mental Activity Seems to Keep the Brain Vital 54005 1Mental Activity Seems to Keep the Brain Vital 54005 2
... cells with the capacity to build fat, according t...l Cell, a Cell Press publication. Although they ...es, transplants of the progenitor cells isolated f...al fat tissue in animals that are otherwise lackin...ses of obesity, a condition characterized by an in...
...gy have shaped not only how we find or share infor...ect just funded by the National Institutes of Heal... next level. , The University of Michigan will le...data needed to develop computer programs that more... data will be housed in a Web-based resource that ...
...m the Herman B Wells Center for Pediatric Research...focusing on a family of blood proteins that they ...f chemotherapy in children and adults. , Their f...geted therapies for leukemia, multiple myeloma and...ed by Kristin T. Chun, Ph.D., assistant professor ...
Other Biology News:Fat-regenerating 'stem cells' found in mice 2New data resource to advance computer-aided drug design 2On the trail of a targeted therapy for blood cancers 2
(Date:11/27/2009)... A mechanised blue dye tes...n to packaging quality assurance one step closer f...contact leak testing machine developed by Sepha...en installed in several local and global pharma-co... address quality assurance and productivity improv...
(Date:11/25/2009)...,, ,, BOCARATON,Fla.,Nov.25/PRNewswire/--...BodyLogicMD.Thenation,slargestandfastestgrowingnet...icallysupervised bioidenticalhormones has grownthe...008-from21to36physicians -andisinprogresstoaddmore...theendofthisyear. ,, Inthepastyear ,BodyLogicMD...
(Date:11/24/2009)... This release is available in German . , Wh...ion cards: RFID tags (Radio Frequency Identificati...ay life. They make it possible to label objects or...equency. The appropriate scanner can read and proc...can be affixed to goods under production condition...
(Date:11/24/2009)...,, CALGARYandBLENHEIM,Ontario,Nov.24/PRNewswire...isacquiringtheassetsofHylandSeeds,adivisionofThomp...eedswillfurtherexpandDowAgroSciences,currentseedsb...artStax(TM) in 2010 andDowAgroSciencesHerbicideT...lcloseisexpectedinthenearfuture. ,, "Thisacquis...
Breaking Biology Technology:Sepha's Blue Dye Test Alternative Brings ‘Complete Automation' To Pharma-Packaging Quality Assurance 2Sepha's Blue Dye Test Alternative Brings ‘Complete Automation' To Pharma-Packaging Quality Assurance 3Nation's Largest Network of Doctors Specializing in Bioidentical Hormones Grows at an Exponential Rate 2Nation's Largest Network of Doctors Specializing in Bioidentical Hormones Grows at an Exponential Rate 3Intelligence inside metal components 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 3
... Multiporator / Electroporator 2510 , , ,... Transformation Protocol , Pr... , , , , , , , ,... Nocardia corallina, , ...am positive, , , Mo...
... Multiporator , , , , , , ...on Protocol , Protocol No. 4308 915.04..., , , , , , ,..., , , Cell type ,..., , Transformation with , ...
... Multiporator , , , , , , ... Protocol , Protocol No. 4308 915.036 ... , , , , , , ...rovascular endothelial cells from , r... , Transfection with , Plas...
Other Biology Technology:Nocardia corallina 2Neurospora crassa 2Primary cells, rat heart endothel 2
GIBCO Newborn Calf Serum from Invitrogen
...d efficient removal of short primers, dNTPs, enzym...products (Figure 1). The simple PureLink bind/wash...tions for fragments >100 bp or >300 bp* , can be p...format , takes ,Two proprietary buffers are supp...
...nute cloning and subsequent sequencing of PCR prod...rimer sites located as close as 33 base pairs from...e amount of vector DNA that needs to be read befor... available. The pCR4-TOPO vector provides 3-T over...
Zebrafish Vitellogenin ELISA System from GE Healthcare, formerly Amersham Biosciences
Biology Products: