Navigation Links
Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke

713 works specifically at that receptor."

Finally, the Hopkins scientists showed that stimulation of EP1 receptors triggers the damage caused when blood flow is suddenly restored after a stroke. The team blocked blood flow in one of the main arteries feeding specific areas of the brain in mice lacking the gene for the EP1 receptor and then restored blood flow after 90 minutes. The area of brain damage (infarct size) in the mice lacking the EP1 gene was only about 57 percent of that seen in normal mice that underwent the same treatment. This provided additional evidence that brain damage caused by ischemia depends in large part on the stimulation of EP1 receptors, the researchers reported.

"Our results strongly suggest that given the side effects associated with COX inhibitors, we should focus our efforts on developing drugs that block the EP1 receptor instead of inhibiting COX-2 activity," said Doré.

Doré has applied for a patent covering the prevention and/or treatment of neurodegenerative diseases by administering agents that block the EP1 receptor.


'"/>

Source:Johns Hopkins Medical Institutions


Page: 1 2 3

Related biology news :

1. Blocking immune cell action increases Alzheimers-associated protein deposits
2. Wisconsin scientists grow critical nerve cells
3. Clam embryo study shows pollutant mixture adversely affects nerve cell development
4. Zebrafish may hold key to understanding human nerve cell development
5. New component of the brakes on nerve regeneration found
6. Cerebral navigation: How do nerve fibers know what direction to grow in?
7. Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves
8. Diabetic nerve therapy shows striking results
9. Malfunctioning bone marrow cells sabotage nerve cells in diabetes
10. UIC researchers show protein routes messages in nerve cells
11. Researchers find molecule that inhibits regrowth of spinal nerve cells
Post Your Comments:
(Date:3/24/2015)... , Mar. 24, 2015 Research and Markets ... and Voice Biometrics - Global Strategic Business Report" report to ... Face and Voice Biometrics in US$ Thousands by the following Segments: ... for the US, Canada , Japan ... , Middle East & Africa ...
(Date:3/24/2015)... GARDENS, Fla. , March 24, 2015 /PRNewswire/ ... identity management solutions, today announced that its U.are.U ... clothing accessory retailer Goorin Bros . to ... Crossmatch biometrics-based solution secures access to the POS ... the increased risk of data breaches. ...
(Date:3/23/2015)... 23, 2015   HOYOS Labs , a leading ... announced that the Company will demonstrate multiple biometrics-based technologies ... consumers at Connect:ID on March 23 through 25, 2015, ... will highlight the IEEE Biometric Open Protocol Standard; free ... enterprise access control system. BOPS was invented by HOYOS ...
Breaking Biology News(10 mins):Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... potential for preventing cardiomyopathy, a form of heart disease that ... scientists have concluded in a new study. Their report, which ... for diabetic cardiomyopathy, appears in ACS, bi-weekly Journal of ... note that people with diabetes have at least twice the ...
... of up to 4.2 C and the end of ... are not revised in the Copenhagen Accord, the international pledge ... conference. Just ahead of the next United ... Tianjin, China, a new report published today, Wednesday, 29 September, ...
... 2010) "Migraine feels like God just punched you in ... his interview on the American Migraine Foundation,s (AMF) new podcast ... crisis." In the interview AMF,s president Barry Baumel MD, ... pain of migraine, how not to be a "nave" patient, ...
Cached Biology News:Climate accord loopholes could spell 4.2-degree rise in temperature and end of coral reefs by 2100 2American Migraine Foundation launches new podcast series 2
(Date:5/1/2015)... , May 1, 2015 ... equities: Genetic Technologies Ltd (NASDAQ: GENE ), ... Fisher Scientific Inc. (NYSE: TMO ), Sequenom ... (NYSE: PKI ). Free research report on ... . On Thursday, April 30, 2015, the NASDAQ ...
(Date:5/1/2015)... -- According to a new market ... by Type (Monoclonal, Polyclonal), by Technology (Hybridoma), by ... Analysis & Global Forecast to 2019", published by ... Market for the forecast period of 2014 to ... Billion by 2019 from $1.425 Billion in 2014, ...
(Date:4/30/2015)... Spirax Sarco, the leader in product ... announce that for the first time in the company’s ... a Queen’s Award for Innovation – the UK’s highest ... of a unique flowmeter. , The Spirax Sarco ... steam flow measurement. The device provides reliable, accurate ...
(Date:4/30/2015)... DIEGO , April 30, 2015   Tamir ... announced today an update on its Ebola antiviral therapy ... Tamir,s leading candidates, TMR004, is currently being evaluated and ... of the battle against Ebola. During the first quarter ... And Leadership Meeting To Accelerate The Evaluation of Potential ...
Breaking Biology Technology:Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4
... Immunotech Laboratories (Pink Sheets: IMMB) is happy ... potential venture for South America, headquartered in Mexico. ... Laboratories, the potential outcome from these discussions, will ... and position the company for a viable regional ...
... FRANCISCO, April 3 VIA Pharmaceuticals, Inc. (Nasdaq: ... development of compounds for the treatment of cardiovascular and ... letter, dated March 31, 2009, from the staff of ... does not currently comply with NASDAQ Marketplace Rule 4310(c)(3). ...
... to leverage technologies for PACS data disaster recoveryCHICAGO, April ... business unit of Siemens Healthcare ( ... Corporation ( www.harris.com ... solutions critical for Picture Archiving and Communication Systems (PACS) ...
Cached Biology Technology:Immunotech Laboratories Announces South American Strategy 2VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 2VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 3VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 4Siemens Healthcare Announces Planned Collaboration with Harris Corporation 2Siemens Healthcare Announces Planned Collaboration with Harris Corporation 3Siemens Healthcare Announces Planned Collaboration with Harris Corporation 4
Collected from sexually matured, mixed breed, mixed sex guinea pigs....
Silica bead method is an economic method of DNA extraction from agarose...
...
...
Biology Products: