"It has long been known that bleach can kill mold. However, dead mold may remain allergenic," said lead author John Martyny, Ph.D., associate professor of medicine at National Jewish. "We found that, under laboratory conditions, treating mold with bleach lowered allergic reactions to the mold in allergic patients."
The need for denaturing or neutralizing mold allergens is a critical step in mold treatment that has not been fully understood. Currently, most recommendations for mold remediation call for removal since dead mold retains its ability to trigger allergic reactions, according to Dr. Martyny.
The researchers grew the common fungus Aspergillus fumigatus on building materials for two weeks, and then sprayed some with a dilute household bleach solution (1:16 bleach to water), some with Tilex?Mold & Mildew Remover, a cleaning product containing both bleach and detergent, and others only with distilled water as a control. They then compared the viability and the allergenicity of the treated and untreated mold.
The researchers found that the use of the dilute bleach solution killed the A. fumigatus spores. When viewed using an electron microscope, the treated fungal spores appeared smaller, and lacked the surface structures present on healthy spores. In addition, surface allergens were no longer detected by ELISA antibody-binding assays, suggesting that the spores were no longer allergenic.
The National Jewish r
Source:National Jewish Medical and Research Center