Navigation Links
Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

Preliminary results from a large, randomized clinical trial for patients with previously untreated recurrent or metastatic breast cancer ?cancer that has spread from the breast to other parts of the body ?show that those patients who received bevacizumab (Avastin? in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same chemotherapy without bevacizumab.

The clinical trial was sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, and conducted by a network of researchers led by the Eastern Cooperative Oncology Group (ECOG). Genentech, Inc., South San Francisco, Calif., which manufactures bevacizumab, provided bevacizumab for the trial under the Cooperative Research and Development Agreement (CRADA) with NCI for the clinical development of bevacizumab.

The Data Monitoring Committee overseeing the trial (known as E2100)* recommended that the results of a recent interim analysis be made public because the study had met its primary endpoint of increasing progression-free survival (the amount of time patients lived without the cancer getting worse).

Preliminary results suggest that patients in the study who received bevacizumab in combination with standard chemotherapy consisting of single-agent paclitaxel had a delay in worsening of their cancer by four months, on average, compared to patients treated with paclitaxel chemotherapy alone. This difference is statistically significant.
“This study is the first to find a benefit of anti-angiogenic therapy in patients with breast cancer and represents a major advance in the treatment of patients with metastatic disease," said Study Chair Kathy D. Miller, M.D., of the Indiana University Medical Center in Indianapolis, Ind. Anti-angiogenic drugs, also called angiogenesis inhibitors, are substances that may prevent angiogenesis, or the formation of blood vessels. In anticancer therapy, a
'"/>

Source:NIH


Page: 1 2 3

Related biology news :

1. Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
2. Combined treatment extends life expectancy for lung cancer patients
3. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
4. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
5. Chemotherapy gel may fight breast cancer and reduce breast deformity
6. Chemotherapy temporarily affects the structures of the human brain
7. Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
8. Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis
9. Survival of heart patients on beta-blockers varies greatly with genetic variation
10. Survival of the selfless - scientists find cheats dont always prosper
11. Survival of the rarest: Fruit flies shed light on the evolution of behavior
Post Your Comments:
(Date:4/1/2015)... 1, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces the second ... is underway to early access pre-order customers. ... at retail outlets including Walmart, Target, AT&T, Dunkin, Donuts, ... was accepted at all outlets and very easy to ...
(Date:4/1/2015)... April 1, 2015   Medisafe ™, the leading ... across iOS and Android smartphones ... biofeedback into the platform to allow patients to track ... the first time, patients will be able to visualize ... impacts important biometrics, such as glucose levels and blood ...
(Date:3/31/2015)...  Elephant Talk Communications Corp. (NYSE MKT: ETAK) ("Elephant ... Defined Network Architecture (ET Software DNA® 2.0) platforms and ... $20.4 million for the year ended December 31, 2014 ... year ended December 31, 2013. At ... its multi-year transition away from its legacy landline business ...
Breaking Biology News(10 mins):NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... viruses or parasites attack, immune system cells unleash the ... trigger inflammation, which, if unchecked, can destroy tissue, induce ... let loose another protein compound to cool down the ... operates is unclear. The leading hypothesis is that these ...
... Research Institute (NHGRI), one of the National Institutes ... targets including the Northern white-cheeked gibbon (Nomascus leucogenys), ... sequence the genome of at least one non-human ... along the evolutionary primate tree and making available ...
... The brain's septum helps prevent epileptic seizures by ... another area of the brain known as the ... Journal of Neurophysiology. The researchers found that, by ... rats, they could reduce epileptic seizures by 86-97 ...
Cached Biology News:Research reveals inner workings of immune system 'thermostat' 2NHGRI announces latest sequencing targets 2NHGRI announces latest sequencing targets 3NHGRI announces latest sequencing targets 4NHGRI announces latest sequencing targets 5NHGRI announces latest sequencing targets 6Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent 2Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent 3
(Date:4/1/2015)... Md. , April 1, 2015  Spherix ... company committed to the fostering and monetization of ... LLC, a privately held full service global investment ... recently issued an industry note featuring Spherix. ... , CFA, a Senior Analyst at Chardan, was ...
(Date:4/1/2015)... April 01, 2015 The concept of “spot ... multi-billion dollar industry. Founder of Fasciology, Ashley Black, says that ... of fat, instead of having to wait for the whole ... that “ prior to fat cooling procedures, the only ... contouring, was liposuction, which is a highly invasive procedure.” It ...
(Date:4/1/2015)... 2015 National recruitment firm Slone ... Brad Allen as Head of Sales at Optimal Medicine, ... market. , Allen brings over 20 years experience ... a number of companies including Dell Services Healthcare, Medsphere ... were a perfect fit for accomplishing the goals Optimal ...
(Date:3/31/2015)... CytoSorbents Corporation (NASDAQ CM: CTSO), a ... treat critically-ill and cardiac surgery patients in multiple ... financial results for the fiscal year ending December ... revenues were a record $3.1M, an increase of ... of $0.8M Highlights for the Year Ending December ...
Breaking Biology Technology:Chardan Capital Issues Industry Note Covering Spherix 2Chardan Capital Issues Industry Note Covering Spherix 3Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 2Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 3Slone Partners Fills Head of Sales at Optimal Medicine 2CytoSorbents Reports Record 2014 Revenue 2CytoSorbents Reports Record 2014 Revenue 3CytoSorbents Reports Record 2014 Revenue 4CytoSorbents Reports Record 2014 Revenue 5CytoSorbents Reports Record 2014 Revenue 6CytoSorbents Reports Record 2014 Revenue 7CytoSorbents Reports Record 2014 Revenue 8CytoSorbents Reports Record 2014 Revenue 9CytoSorbents Reports Record 2014 Revenue 10CytoSorbents Reports Record 2014 Revenue 11
... growth company of diversified businesses, ... Transportation Accessories Group has acquired ... zinc plating services. Chem-Chrome is ... has been a longtime processor ...
... Software, worldwide leader in e-document ... Fax and VSI-FAX(R) product families, ... 3.0. This new solution allows ... more efficiently, effectively, and economically ...
... nanoscale device developed by a University of Wisconsin-Madison Engineering ... electrons in such devices as laptop computers and provide ... This device will allow researchers to study ... heat dissipation on single electron transport in transistors. ...
Cached Biology Technology:Cool Computers 2Cool Computers 3
cysteine and glycine-rich protein 2,...
... inhibitor (IC50 = 59.2 M). ... 32 O 13 MolWeight: ... RT CAS: ... Soluble to 100 mM in DMSO IUPAC: ...
HSPBP1 Antibody...
1, 2 or 8 PreMixes are included as part of the FailSafe™ PCR System....
Biology Products: