Navigation Links
Bacterial walls come tumbling down

ure. They then were able to repeat the feat to reveal the crystal structure of the enzyme combined with the animal antibiotic.

Their findings help reveal how the enzyme prepares to assemble the bacteria's sugar-coating by plucking sugars from a fat-sugar package known as lipid II. The antibiotic, which is another kind of sugar-lipid, probably mimics the lipid II molecule by tucking into a fold in the enzyme and taking up the space needed to bind to lipid II, the researchers believe. "We would like to see the enzyme in a complex with its natural substrates as well as with inhibitors," Lovering said. In the meantime, scientists now have the details of its shape and key contact points between enzyme and antibiotic.

The enzyme structure is the first ever solved of a member of a family of enzymes that remove sugars from lipids and attach them to other sugars. This process is used in a wide range of biochemical reactions, including allergic responses and cell signaling in cancer.


'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3

Related biology news :

1. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
2. Bacterial genome sheds light on synthesizing cancer-fighting compounds
3. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
4. Say what? Bacterial conversation stoppers
5. Bacterial protein mimics host to cripple defenses
6. Bacterial switch gene regulates how oceans emit sulfur into atmosphere
7. Bacterial protein shows promise in treating intestinal parasites
8. Bacterial response to oxidation studied as toxin barometer
9. Newly discovered protein kills anthrax bacteria by exploding their cell walls
10. No cell walls, no new cancer cells
11. Learning to fight an adversary that wont stay down
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Bacterial walls come tumbling down

(Date:8/27/2014)... of studies have shown that excessive iron ... Parkinson,s disease. Previous studies from Chunyan Guo ... China have shown that baicalin prevented iron ... metal transporter 1 expression, and increased ferroportin ... rotenone-induced Parkinson,s disease rats. However, the relationship ...
(Date:8/27/2014)... that can be found in both unprocessed and processed ... Denmark have been infected with Listeria from ... The bacterium is notoriously difficult to fight because it ... in its surroundings, says Associate Professor Birgitte Kallipolitis, University ... of Biochemistry and Molecular Biology, she has published a ...
(Date:8/26/2014)... over a colony of harmful bacteria, biofilms make ... protected in a biofilm pose a significant health ... to treatment, and biofilm-protected bacteria account for some ... and are 50 to 1,000 times more resistant ... essence, we may have stumbled onto a magic ...
Breaking Biology News(10 mins):Researchers discover why Listeria bacterium is so hard to fight 2Researchers discover why Listeria bacterium is so hard to fight 3Breakthrough antibacterial approach could resolve serious skin infections 2Breakthrough antibacterial approach could resolve serious skin infections 3
... energy produced by cars, machines, and industry around the world ... but researchers have found a new way to make "thermoelectric" ... amounts of energy. And it,s based on a device ... Chemists at Oregon State University have discovered that simple ...
... team has turned their newly developed 3-D microscope technology ... use. U of A engineering professor Dileepan ... system called Virtual Reflected-Light Microscopy. The technology consists of ... that moves the objects being photographed and software programs ...
... Paul Kenis and James Slauch have been named ... university,s most talented teachers, scholars and researchers. Kenis, ... in the field of micro fluidics and the development ... health. These tools include the creation of evaporation-based ...
Cached Biology News:Microwave ovens a key to energy production from wasted heat 2Microwave ovens a key to energy production from wasted heat 3University of Illinois faculty members named University Scholars 2
(Date:8/27/2014)... DUBLIN , Aug. 27, 2014 ... the "Global Enzyme for Pulp & Paper Industry ... The Global Enzyme for Pulp & Paper Industry ... the current state of the global enzyme for pulp ... basic overview of the industry including definitions, classifications, applications ...
(Date:8/27/2014)... , Aug. 27, 2014  ARCH Venture ... firms investing in the development of seed and ... eighth venture fund closed with more than $400 ... its $250 million subscription target by more than ... VIII shows the strength and potential of our ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Riviera ... is announcing the creation of the Sancilio Scientific ... take the SCI’s philosophy of looking to nature ... and development actions are based on sound scientific ... Scientific Advisory Board provides a vehicle for SCI ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 After the ... reason that the next beverage craze is going to ... today that formulators can use Stress Relief energy pattern ... in the making of a beverage, including minerals, herbs ... stress-generated energy, channeling that power into rapid recovery and ...
Breaking Biology Technology:Global Enzyme for Pulp & Paper Industry Report 2014 2Latest ARCH Venture Partners Fund Closes Above $400 Million 2Latest ARCH Venture Partners Fund Closes Above $400 Million 3New Sancilio & Company, Inc. Scientific Board 2New Sancilio & Company, Inc. Scientific Board 3Stress Relief: 1 Way to De-Stress Your Beverage Formula 2Stress Relief: 1 Way to De-Stress Your Beverage Formula 3Stress Relief: 1 Way to De-Stress Your Beverage Formula 4
... April 15 /PRNewswire-FirstCall/ - BioMS Medical Corp. (TSX:,MS), ... sclerosis (MS), today,announced that the independent Data Safety ... on-going MAESTRO-03 U.S. pivotal phase III,clinical trial of ... and,recommended that the trial continue., This was ...
... Bionovo Inc.,(Nasdaq: BNVI ) will present findings on ... BN107 and BN108 at the American Association of,Cancer Research ... in San,Diego, CA, April 12 - 16, 2008., ... cell,apoptosis (cell death) induced by BN107 and BN108. As ...
... ST. JOSEPH, Mich., April 15 GeneGo, Inc., ... The Scripps,Translational Science Institute has joined the MetaMiner ... build the first systems,biology and pathway analysis platform ... will vote on deliverables that will include,disease specific ...
Cached Biology Technology:BioMS Medical's phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board 2Bionovo to Present Recent Findings of BN107 and BN108, Its Anticancer Agents, at the American Association of Cancer Research 2The Scripps Translational Science Institute Joins The MetaMiner Cardiac Consortium 2
NORMAL DONOR DONKEY SERUM...
... EPS 301 Power Supply, 1. 300 ... voltage or constant current modes.Single-unit increments ... and reproducibility.Suitable for submarine, mini vertical, ... well as semidry and mini tank ...
B3-1...
Human CCL26/Eotaxin-3 MAb (Clone 115002)...
Biology Products: