PathwayStudio?Central builds pathways from microarray data, identifies biomarkers, and models drug responses. The software comes with ResNet?database of 500,000+ functional relationships and MedScan?tool for automatic extraction of information from scientific literature.
ResNet?database of functional relationships for human, rat and mouse contains 52,000 annotated mammalian proteins, 40,000 chemicals, and over 500 thousand total functional relationships, among which there are 42,000+ physical protein-protein interactions, 46,000+ facts of gene expression regulation, and about 160,000 links between 1779 human diseases and individual proteins.
ResNet was compiled with MedScan?unique Natural Language Processing (NLP)-based tool. MedScan?leverages hand-crafted dictionaries of protein and chemical names, and precise text parsing and pattern matching algorithms specifically developed for biological text analysis.
“PathwayStudio?Central helps scientists to keep current with literature using embedded MedScan information extraction tool that can “read?scientific text and extract functional relationships on the fly? said Ilya Mazo, President of Ariadne Genomics. “They can get an immediate view of all known relationships for a protein or a small molecule, build pathways from gene lists or results of PubMed searches, or predict networks from the gene expression data.?/p>
PathwayStudio?Central is a scalable solution that can be easily deployed in a lab or throughout an entire organization, enabling pathway data sharing and user rights management. Server-side network analysis algorithms and MedScan informat