Navigation Links
Applied scientists create wrinkled 'skin' on polymers

Applied scientists demonstrated a new method for developing wrinkled hard skins on the surface areas of polymers using a focused ion beam. By controlling the direction and intensity of the ion beam, the researchers literally sculpted patterns on flat areas of polydimethylsiloxane, a silicon-based organic polymer (more commonly known as the primary ingredient in Silly Putty). The technique has potential use for biological sensors and microfluidic devices and may offer new ways to build custom-made cell templates for tissue engineering.

The work is a collaboration among researchers at Harvard University and Seoul National University. The Harvard group consisted of John W. Hutchinson, Abbott and James Lawrence Professor of Engineering, Myoung-Woon Moon, Post-doctoral Fellow, and Ashkan Vaziri, Lecturer on Engineering and Research Associate in Applied Mechanics, all of Harvard Engineering and Applied Sciences. Their findings were published in the Proceedings of the National Academy of Sciences. The researchers have also filed for a U.S. patent covering the discovery.

"This technique is a one-step process for creating wrinkled skins," explains Vaziri. "The method is more robust compared with traditional techniques. The patterns can be generated along desired paths by simply controlling the relative movement of the ion beam and polymeric substrate. It's almost like using an airbrush on fabric. At a smaller scale the desired morphology of wrinkles can be achieved by controlling the ion beam intensity."

Because only the areas exposed to the beam are affected, the method enabled the scientists to create a variety of patterns--from simple one-dimensional wrinkles to peculiar and complex hierarchical nested wrinkles--along desired paths. Specific examples to date include "S" shapes, circular patterns, and long horizontal channels akin to the repeating tines of a closed zipper.

"Irradiation by the ion beam alters the chemical composition of t he polymer close to its surface and forms a thin stiff skin which wants to expand," explains Vaziri. "The consequent mismatch between the mechanical strain of the generated stiff skin and the underlying polymeric substrate, almost like a tug-of-war, buckles the skin and forms the wrinkle patterns."

Such patterns can be used in the construction of microfluidic devices for particle separation and mixture and also have potential use in designing biosenors. The researchers have also started a close collaboration with scientists at the Harvard-MIT Division of Health Sciences and Technology aimed at exploring the behavior of living cells on these patterned substrates. Such research may lead to the development of an effective and robust method to build custom templates for engineering and growing tissues.

"We are approaching this field of research from various directions," says Vaziri. "At the moment we are looking at the effect of ion beam energy and have been able to reduce the wavelength of the wrinkles to 50 nanometers. Manipulation at such a small scale makes this method even more attractive. We are also building multifunctional microfluidic devices for the mixing of flow at very small scales and stretching of proteins and DNA. These new efforts, while at early stages of development, are very promising."


'"/>

Source:Harvard University


Related biology news :

1. Applied Biosystems Introduces Advanced Gene Expression Service Provider Program
2. Wisconsin scientists grow critical nerve cells
3. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
4. UAB scientists discover the origin of a mysterious physical force
5. Fox Chase Cancer Center scientists identify immune-system mutation
6. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
7. U-M scientists find genes that control growth of common skin cancer
8. UCLA scientists transform HIV into cancer-seeking missile
9. RNA project to create language for scientists worldwide
10. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
11. To control germs, scientists deploy tiny agents provocateurs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2018)... ... August 25, 2018 , ... Maire ... a biofield energy treated nutraceutical to reduce inflammation and autoimmune disorders and improve ... blood, as well as inflammation. The following data was reported:, ...
(Date:8/23/2018)... (PRWEB) , ... August 21, 2018 , ... ... the genomes of diverse cell types and species for the robust functional interrogation ... tool for the development of T-cell based immunotherapies, the study of the autoimmunity, ...
(Date:8/23/2018)... ... August 22, 2018 , ... Lajollacooks4u is proud to have hosted a variety of groups ... Companies, such as Illumina, Qualcomm, Hewlett Packard, Sequenom and more, have all visited the ... , Part of the reason clientele return is due to Lajollacooks4u’s signature team-building ...
Breaking Biology News(10 mins):
(Date:9/12/2018)... KENT, Wash. (PRWEB) , ... September 11, 2018 ... ... systems, is proud to add flat sheet Forward Osmosis (FO) membranes from Fluid ... new FO membranes manufactured by FTS H2O are constructed from cellulose triacetate (CTA) ...
(Date:9/7/2018)... ... 05, 2018 , ... Now available on live stream, the NanoScientific Symposium on ... 2018. With a panel of industry leaders from Harvard, Cornell, RPI, IBM, SUNY and ... from experts in the field. Register today to be a part of the ...
(Date:9/7/2018)... LEXINGTON, Mass. (PRWEB) , ... September 06, 2018 ... ... in medical device compliance and commercialization, is releasing the agenda for its upcoming ... from across life science industries discussing the latest challenges, opportunities, and approaches to ...
(Date:9/7/2018)... ... 2018 , ... Akadeum Life Sciences today announced it has appointed George Dunbar ... leader of numerous biotech companies. , He most recently served as president and ... Street Capital in St. Louis, MO. Prior to ISTO, he was a Venture ...
Breaking Biology Technology: