Navigation Links
Antivirals effectively curb influenza virus

authors reviewed the effects of each antiviral on infectiousness and pathogenicity ?the ability of the influenza virus to cause overt disease. Pathogenicity in controls ranged from 44 percent to 66 percent. Efficacy in reducing pathogenicity for zanamivir was 52 percent and 56 percent in the two zanamivir studies; for oseltamivir, it was 56 percent and 79 percent. The researchers found that both drugs were highly preventive against influenza illness, with oseltamivir at 81 percent efficacy and zanamivir at 75 percent. Thus, the preventive use of either product reduced by 75 percent to 81 percent the chance that an exposed person would become ill with influenza.

The researchers' analysis found a significant reduction in infectiousness, as defined by reductions in influenza illnesses in household contacts, when oseltamivir was used for treatment of ill persons, but not when zanamivir was administered. Although these results are of interest, the authors stress that the numbers were small and combined estimates from two studies for each drug were used in both instances. Furthermore, oseltamivir treatment of ill persons did not appear to reduce the frequency of influenza infection in their contacts.

In exploring the reasons for oseltamivir's greater effects on infectiousness, the authors speculated that the different modes of administration ?oral for oseltamivir and inhaled for zanamivir ?and resultant upper-respiratory viral levels could be the key, with zanamivir not reaching or affecting influenza virus in the nose. While both antivirals reduced cough, in earlier studies inhaled zanamivir did not significantly reduce nasal symptoms. In the paper the authors discussed the possibility that infectious droplets inhaled and exhaled from the nose may be important in viral transmission, thus orally administered oseltamivir might have an advantage in limiting spread.

In addressing the limitations to their research, the authors call for further stu
'"/>

Source:Fred Hutchinson Cancer Research Center


Page: 1 2 3

Related biology news :

1. New study: Sexually transmitted disease treatment can be effectively administered by sex partners
2. New vaccine protects more effectively against tuberculosis
3. Bird flu study highlights need to vaccinate flocks effectively
4. Experimental RNA-based drug kills prostate cancer cells effectively and safely
5. Computers to be used to find blueprint for new influenza drug
6. Less virulent strains of avian influenza can infect humans
7. Drug resistant avian influenza viruses more common in Southeast Asia than North America
8. New vaccine platform may fight infections with causes from influenza to bioterrorism
9. First big influenza genome study reveals flu evolution
10. Web model of influenza-host lifecycles will aid scientists in creating anti-viral drugs
11. New influenza vaccine takes weeks to mass produce
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Antivirals effectively curb influenza virus

(Date:11/5/2014)... career to understanding the Earth,s climate and communicating ... deputy director and regional climatologist for the Western ... Redmond has more than three decades of experience ... data to the general public. , At its ... December 15-19, 2014 the American Geophysical Union (AGU) ...
(Date:11/4/2014)... School of Medicine announced today that it is ... by the Bill & Melinda Gates Foundation. ... and Reproductive Sciences; and Vice Chair of Research ... Medicine will pursue an innovative global health and ... Assess Fetal Neurodevelopment.", Grand Challenges Explorations (GCE) funds ...
(Date:11/4/2014)... 4, 2014) – A majority of Madagascar,s 101 species ... have serious consequences for the rainforests they call home. ... positive impacts lemurs can have on rainforest tree populations, ... could have on the region,s rich biodiversity. , A ... eaten by lemurs. Lemurs in turn disperse the ...
Breaking Biology News(10 mins):Nevada climatologist to be honored at AGU Fall Meeting for lifetime of public outreach 2Temple University School of Medicine receives Grand Challenges Explorations grant 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... 250 million year-old species of large, meat-eating amphibians ... McGill University. Their findings published in today's issue ... carnivores from the Republic of Niger in West ... in this area," says McGill paleontologist, and co-author, ...
... relationship between a wasp species and a newly ... light on how bacteria can be successfully utilized ... microbes. In the new work, researchers show that ... Streptomyces bacteria in unique structures within its antennae ...
... found only in germ-line cells results in infertility in ... from researchers at the University of Pennsylvania School of ... Penn's Center for Research in Reproduction and Women's Health, ... to a new type of contraceptive for both men ...
Cached Biology News:Symbiotic bacteria protect hunting wasps from fungal infestation 2Of mice and men's (and women's) contraceptives 2
(Date:11/22/2014)... 2014 On November 17th Chicago start-up ... Emerging Medical Technologies Summit in San Francisco to take ... regarded among Silicon Valley investors and technology elites as ... win also positions Briteseed to move on to ... 2015 and compete with other elite innovation finalists for ...
(Date:11/21/2014)... , November 21, 2014 , ... comercial   Mariano Rodríguez es elegid vicepresidente ... KLOX está en marcha para comenzar de forma ... de heridas de reciente aprobación en Europa   , ... se complace al anunciar los siguientes nombramientos: ...
(Date:11/21/2014)... The California Healthcare Institute ... representing leading California academic institutions, biotechnology, medical device, ... today released a report revealing that California ... The trend shows a 4 percent increase between ... Industry Report indicates that, while biopharmaceutical and ...
(Date:11/21/2014)... Dallas, Texas (PRWEB) November 21, 2014 ... China Sodium Ferrocyanide Industry” is a professional and ... it provides Sodium ferrocyanide information, like its ... well as industry overview. This report covers the ... well as global (such as the US, Europe, ...
Breaking Biology Technology:Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3KLOX Technologies anuncia sus nombramientos ejecutivos 2KLOX Technologies anuncia sus nombramientos ejecutivos 3KLOX Technologies anuncia sus nombramientos ejecutivos 4KLOX Technologies anuncia sus nombramientos ejecutivos 5California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 2California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 4Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 2Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 3
... SAN FRANCISCO, March 27 Nile Therapeutics, Inc. ... development of novel therapeutics for heart failure patients, announced today ... (IND) application materials that Nile submitted to the U.S. Food ... Company,s Phase IIb clinical trial with CD-NP for the treatment ...
... (Nasdaq: WCRX ) announced today that its ... Drug Application for WC 3016, a low-dose oral contraceptive, ... Warner Chilcott , Warner Chilcott is a ... healthcare and dermatology segments of the U.S. pharmaceuticals market. ...
... Companies Will Offer a Personal Health Record ... Keep ,First Puppy, Healthy and Kissably Sweet ... MMR Information Systems, Inc. (OTC Bulletin ... subsidiary, MyMedicalRecords, Inc. (collectively, "MMR") provides consumer-controlled ...
Cached Biology Technology:Nile Therapeutics Provides Update on Phase II CD-NP Clinical Trial for Acute Heart Failure 2Warner Chilcott Announces NDA Submission for Low Dose Oral Contraceptive 2Warner Chilcott Announces NDA Submission for Low Dose Oral Contraceptive 3MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 2MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 3MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 4
... used to quantitate double-stranded DNA (dsDNA) in solution, ... With this kit, DNA is stained with Hoechst ... VersaFluor or other fluorometer. The kit quantitates dsDNA ... to 5 micrograms per ml and contains Hoechst ...
... stimulating factors for assays of mouse hematopoietic ... fetal liver. Suitable for the growth ... when added to methylcellulose at a final ... Will also support growth of mouse ...
ImmunoPure Plus Immobilized Protein G, , , , Support: Cross-linked 6%, beaded agarose , Capacity: > 20 mg human IgG/ml of gel ...
...
Biology Products: