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Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

homa or other non–AIDS-defining cancers," the authors write. "Focusing on ways to encourage persons infected with HIV to quit smoking would be effective in reducing lung cancer in these persons."

In an editorial, Eric A. Engels, M.D., and James J. Goedert, M.D., of the National Cancer Institute, revisit the history of the AIDS epidemic and how the knowledge of cancer and immune diseases has grown since it began. They note that questions remain about the types and severity of cancers that will appear in coming years among patients on HAART, who have less severe but prolonged immunosuppression. "Controlling the epidemic and ameliorating the suffering of persons living with HIV/AIDS are more urgent than ever," they write. "Continued study of cancer in people with HIV/AIDS will redound to give us clues about cancer etiology to the benefit of all."

Citations:
# Article: Clifford GM, Polesel J, Rickenbach M on behalf of the Swiss HIV Cohort Study, Dal Maso L, Keiser O, Kofler A, et al. Cancer Risk in the Swiss HIV Cohort Study: Associations With Immunodeficiency, Smoking, and Highly Active Antiretroviral Therapy. J Natl Cancer Inst 2005;97:425?2.

# Editorial: Engels EA, Goedert JJ. Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome and Cancer: Past, Present, and Future. J Natl Cancer Inst 2005;97:407?.


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Source:Journal of the National Cancer Institute


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