Navigation Links
Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

colleagues hypothesized that the presence of antiretroviral drugs in breast milk may reduce mother-to-child transmission through either direct inhibition of HIV replication in the breast milk, or by preventing infection from taking hold in the infant.

The high drug concentrations raised the possibility of some risks, as well as benefits, however. Such levels may be high enough to cause adverse effects associated with the drugs, such as rash, neutropenia, and anemia, and to lead to the emergence of drug-resistant virus.

For the second study, the researchers examined the ability of combination antiretroviral therapy to reduce HIV-1 RNA and DNA levels in breast milk. They measured these levels in two groups: 26 women who received nevirapine, lamivudine, and zidovudine beginning during pregnancy or postpartum, and 25 women from an earlier time period with comparable HIV disease, who did not receive antiretroviral therapy because it was unavailable to them at the time they were breastfeeding.

The results indicated that antiretroviral therapy suppresses HIV RNA in breast milk and may therefore reduce mother-to-child transmission of HIV during breastfeeding. Eighty-eight percent of the women receiving antiretroviral therapy had fewer than 50 copies/ml of HIV-1 RNA in their breast milk, compared with 36 percent of the women not taking therapy. This represents a statistically significant difference.

However, there was no such difference for HIV-1 DNA, which some studies suggest also contributes to mother-to-child transmission. One possible explanation for this lack of association between antiretroviral therapy and HIV DNA levels, the investigators hypothesized, may be the short duration of treatment in the study (a median of 98 days). Combination antiretroviral therapy may reduce HIV DNA in breast milk more slowly than HIV RNA, thus raising the risk that, when treatment duration is short, HIV DNA-associated transmission may occur despite the
'"/>

Source:Infectious Diseases Society of America


Page: 1 2 3

Related biology news :

1. Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
2. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
3. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
4. Gene Therapy For Parkinsons Disease Moves Forward In Animals
5. Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments
6. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
7. Discovery Promises Simpler Therapy for Sickle Cell Disease
8. Gene Therapy Cures Inherited Liver Disease In Rats
9. HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find
10. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
11. Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
Post Your Comments:
(Date:12/10/2014)... 2014 Research and Markets ( ... "Biometrics Market in Japan 2014-2018" report ... http://photos.prnewswire.com/prnh/20130307/600769 The integration of biometrics ... banking and upgradation of the driver,s license is ... market. Besides the aforementioned projects, biometrics is being ...
(Date:12/3/2014)...   Marvin Test Solutions , a trusted ... military, aerospace, and manufacturing organizations, today announced the ... TS-900 PXI semiconductor test platform . The TS-960 ... to customers at a fraction of the footprint ... "Our semiconductor customers asked for ...
(Date:11/21/2014)... 2014 C-Labs LLC, a leading provider of ... (IoT), today announced the appointment of John Traynor ... a strategic advisor to the firm, Mr. Traynor will ... is based out of the C-Labs office in ... Chris Muench , Chief Executive Officer. Photo ...
Breaking Biology News(10 mins):Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... the park can dramatically change natural ecosystems, according to ... of California, Berkeley. These findings could have important implications ... in the San Francisco Bay Area that allow only ... nearby nature reserves that allow no public access. Evidence ...
... cancer centers have confirmed that an analysis involving a panel ... patients will have the worst survival. The finding could one ... needs more aggressive treatment. The study, the largest of ... The researchers looked at 442 lung cancer tissue samples ...
... almost as soon as it,s begun promises to reduce the ... Chemistry & Industry (C&I) magazine. Drilling ... of people off visiting their dentist every year. ... in five years from now, is based on Raman spectroscopy ...
Cached Biology News:Outdoor enthusiasts scaring off native carnivores in parks 2Outdoor enthusiasts scaring off native carnivores in parks 3Outdoor enthusiasts scaring off native carnivores in parks 4Gene panel predicts lung cancer survival, study finds 2End in sight for the dreaded dentist drill 2
(Date:12/24/2014)... 23, 2014 Pipette.com announces their ... followers can submit their #HolidayInTheLab pictures for a chance ... mates. , For those struggling to think of a ... Holiday in the Lab Contest provides the ideal holiday ... to send pictures of their chemistree, holiday sweaters, ...
(Date:12/24/2014)... , Dec. 23, 2014  Rock Creek Pharmaceuticals, ... it has filed a Clinical Trial Application (CTA) with ... products Regulatory Agency (MHRA) seeking regulatory approval to initiate ... molecule, Anatabine Citrate. Contingent on the Company ... a Phase I trial to assess the safety, tolerability ...
(Date:12/22/2014)... HILL, N.C. , Dec. 22, 2014 /PRNewswire/ ... today announced that it has signed a letter ... company that has developed and patented a nanotechnology-based ... medical diagnostics products that enable rapid on-site collection ... alcohol use/abuse and health issues in an immediate, ...
(Date:12/22/2014)... Fertility Associates of Memphis has announced a ... a network of more than 20 contributing fertility ... fast access to a national pool of frozen ... Associates of Memphis is the only fertility clinic in ... Dr. William Kutteh , director of Fertility Associates ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3ALNE Announces Intention To Acquire BioTechPharma 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
... good one: pulling the states world-class health care technology ... well into the future. , ,The 20th Annual ... and Wednesday at Madisons Monona Terrace Convention Center, will ... the states burgeoning life sciences industry. The Wisconsin Technology ...
... biotech industry, a well educated work force and citizens who ... billion budget deficit and a per capita income almost $1000 ... average in citizens with a 4-year degree, which means we ... state of our economy presents a complex problem that cannot ...
... WI - A Wisconsin heath information technology software ... software is expanding its solutions to include a ... records with data from other hospital computer systems. ... a Hartford, Wisconsin developer of systems that allows ...
Cached Biology Technology:Conference Zeroes in on Homegrown Innovation - 20th Life Science & Venture Conference Full of High-Tech Insights 2WARF Collaboration a Win-Win for Wisconsin 2WARF Collaboration a Win-Win for Wisconsin 3API Improves Hospital Efficiency 2
Rabbit polyclonal antibody to Glutathione-S-Transferase (GST)...
... GCMS-QP2010s Gas Chromatograph/Mass Spectrometer, utilizing many ... GCMS-QP2010 Plus, offers high throughput and ... excellent performance-to-cost ratio. Like the GCMS-QP2010 ... linear velocity for optimum separation, 20 ...
Chicken polyclonal antibody to Glutathione-S-Transfrease (GST)...
... a single-channel sample processing head, an 8-channel ... dispenser all in one compact, affordable product. ... tips, the Precision XS autoclavable and organic ... for transferring larger volumes. Intuitive Precision Power ...
Biology Products: