Navigation Links
Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world.

Researchers in the first study found mothers pass antiretroviral medications on to their breastfeeding infants in concentrations high enough to prevent infection. The second study showed levels of HIV RNA in breast milk are lower in mothers taking antiretroviral therapy than those who are not. Both studies appear in the September 1 issue of The Journal of Infectious Diseases, now available online.

Without antiretroviral therapy for an HIV-infected mother or her baby, transmission of HIV-1 through breast milk occurs in approximately 9 to 16 percent of breastfed infants. In the developing world, many HIV-infected mothers breastfeed rather than use formula due to the high cost of formula, lack of a safe water supply, and cultural norms.

Roger L. Shapiro, MD, MPH, of the Harvard School of Public Health, led the research in Botswana. In the first study, the researchers measured the concentrations of three antiretroviral drugs, nevirapine, lamivudine, and zidovudine, in the blood and breast milk of 20 HIV-infected women, and in the blood of their uninfected breastfeeding infants. All of the mothers had been receiving this combination of antiretroviral therapy continuously for at least six weeks prior to the start of the study, and all of the infants received a single dose of nevirapine and continuous zidovudine therapy after birth.

At either two or five months after delivery, all three drugs taken by the mothers were found in breast milk in concentrations similar to or higher than those found in the mothers' blood. In samples of the infants' blood, the investigators observed high, inhibitory concentrations of nevirapine that were above those thought necessary to protect against HIV infection. Dr. Shapiro and
'"/>

Source:Infectious Diseases Society of America


Page: 1 2 3

Related biology news :

1. Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
2. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
3. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
4. Gene Therapy For Parkinsons Disease Moves Forward In Animals
5. Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments
6. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
7. Discovery Promises Simpler Therapy for Sickle Cell Disease
8. Gene Therapy Cures Inherited Liver Disease In Rats
9. HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find
10. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
11. Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
Post Your Comments:
(Date:5/21/2013)... in the body, stem cells in the blood ... into mature immune cells that can fight off ... these cell populations, potentially leading to the development ... a team of researchers led by biologists at ... that, in mouse models, the molecule microRNA-146a (miR-146a) ...
(Date:5/21/2013)... most deadly when they metastasize and spread tumors throughout ... becomes very difficult for doctors to locate and treat ... the University of Missouri have found a way to ... they may be in the body. Michael Lewis, an ... Veterinary Medicine, says being able to target secondary tumors ...
(Date:5/21/2013)... at Chicago College of Medicine will study gender differences in ... energy source -- and how changes in fat metabolism play ... 4-year grant from the National Heart, Lung and Blood Institute. ... for energy. These changes may play a major role in ... and women, says E. Douglas Lewandowski, director of the UIC ...
Breaking Biology News(10 mins):Keeping stem cells strong 2MU researchers develop radioactive nanoparticles that target cancer cells 2Do men's and women's hearts burn fuel differently? 2
... and A*STAR,s Experimental Therapeutics Centre (ETC) today announced ... ETC,s new Singapore Screening Centre. This partnership will ... to biomedical researchers, enabling highly efficient drug screening ... conducts high-throughput screening to identify potential drug candidates ...
... This release is available in German . , ... membrane for the absorption of viruses like hepatitis C, herpes, ... germs. However, certain viruses, such as the human immunodeficiency virus ... membrane. Just how this infiltration occurs on a molecular level ...
... A "four-eyed" fish that sees simultaneously above and below ... how gene expression allows organisms to adapt to their environment. ... student, found a sharp divide between the upper and lower ... 12-inch fish closely related to guppies. The findings were published ...
Cached Biology News:Agilent Technologies and A*STAR launch all-in-one drug screening platform 2Scavenger cells accomplices to viruses 2UBC graduate student discovers key to 'bifocals' in mangrove fish species 2
(Date:5/21/2013)... study led by George Washington University Professor Tianshu ... ice in small droplets is strongly size-dependent, an ... nanoscale. The formation of ice at the nanoscale ... answer also has important implications for climate research ... ice from supercooled water is generally initiated by ...
(Date:5/21/2013)... , May 21, 2013 The ... and Transplant Association) is the biggest congress in ... therapy. Nearly 10,000 participants are in Istanbul ... latest research findings. New pioneering studies have been presented: ... FERRIC PYROPHOSPHATE (SFP) ADMINISTERED VIA HEMODIALYSATE REDUCES ESA USE" ...
(Date:5/21/2013)... Raleigh, NC (PRWEB) May 21, 2013 ... and financial services company for clinical trials, announced ... Aggregate Spend Solutions, LLC. Clinverse’s ClinPay® FLS ... automated investigator payment process. SpendMD ™, ... only complete solution for tracking and reporting transfer ...
(Date:5/21/2013)... According to a new market ... "Biochip Products and Services Market (Microarrays, Reagents, Drug Discovery, ... Share, Growth, Trends and Forecast, 2012 - 2018," the market was valued ... to grow at a CAGR of 10.1% from 2012 ... 4.7 billion in 2018. Browse the full ...
Breaking Biology Technology:Study led by GW professor provides better understanding of water's freezing behavior at nanoscale 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 3Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 2The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 4The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 5
... and CEO of Epic Systems , made a rare ... Promega BTC Center. The audience heard the CEO's perspective on ... company. , ,For over twenty years, Judy Faulkner had never ... participate on outside company boards or committees. The crowd was ...
... security conference and stayed at a hotel, which promoted wireless ... had implemented it so only those on the first floor ... purchase wireless Internet service when Im at seminars because I ... office. Out of curiosity, on my second night at the ...
... that it is producing the Wisconsin Intellectual Capital in ... from 8:30 a.m. to 3:45 p.m. at the Country ... medical device and technology cluster is a key element ... of Commerce (Commerce) Secretary Cory L. Nettles. This presentation ...
Cached Biology Technology:Epic's Founder Judy Faulkner Speaks on Culture, Business Beliefs, and Recruiting: WTN Exclusive Coverage 2Epic's Founder Judy Faulkner Speaks on Culture, Business Beliefs, and Recruiting: WTN Exclusive Coverage 3Wireless Are you at Risk and Liable? 2Wireless Are you at Risk and Liable? 3Wireless Are you at Risk and Liable? 4Medical Technologies and Devices Symposium 2
Human GATA-2 Affinity Purified Polyclonal Ab...
...
... priced, full ring small animal imaging PET ... microPET R4 low retail price, it outperfoms ... count rate performance, energy resolution, timing resolution, ... small animal PET (Positron Emission Tomography) imaging ...
... versatile liquid handling platforms and flexible robotic ... of life science applications.The Freedom EVO platform ... 100, 150 and 200 cm), giving all ... will advance with their application needs. ...
Biology Products: