Navigation Links
Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world.

Researchers in the first study found mothers pass antiretroviral medications on to their breastfeeding infants in concentrations high enough to prevent infection. The second study showed levels of HIV RNA in breast milk are lower in mothers taking antiretroviral therapy than those who are not. Both studies appear in the September 1 issue of The Journal of Infectious Diseases, now available online.

Without antiretroviral therapy for an HIV-infected mother or her baby, transmission of HIV-1 through breast milk occurs in approximately 9 to 16 percent of breastfed infants. In the developing world, many HIV-infected mothers breastfeed rather than use formula due to the high cost of formula, lack of a safe water supply, and cultural norms.

Roger L. Shapiro, MD, MPH, of the Harvard School of Public Health, led the research in Botswana. In the first study, the researchers measured the concentrations of three antiretroviral drugs, nevirapine, lamivudine, and zidovudine, in the blood and breast milk of 20 HIV-infected women, and in the blood of their uninfected breastfeeding infants. All of the mothers had been receiving this combination of antiretroviral therapy continuously for at least six weeks prior to the start of the study, and all of the infants received a single dose of nevirapine and continuous zidovudine therapy after birth.

At either two or five months after delivery, all three drugs taken by the mothers were found in breast milk in concentrations similar to or higher than those found in the mothers' blood. In samples of the infants' blood, the investigators observed high, inhibitory concentrations of nevirapine that were above those thought necessary to protect against HIV infection. Dr. Shapiro and
'"/>

Source:Infectious Diseases Society of America


Page: 1 2 3

Related biology news :

1. Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
2. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
3. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
4. Gene Therapy For Parkinsons Disease Moves Forward In Animals
5. Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments
6. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
7. Discovery Promises Simpler Therapy for Sickle Cell Disease
8. Gene Therapy Cures Inherited Liver Disease In Rats
9. HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find
10. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
11. Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
Post Your Comments:
(Date:9/22/2014)... (Sept. 22, 2014) As genetic sequencing technologies continue ... is a critical need to establish appropriate policies and ... experts have said. A special policy issue of the ... online today and edited by experts with the Center ... of Medicine gives policy makers the tools to jumpstart ...
(Date:9/22/2014)... fishes that manufacture their own "antifreeze" proteins to ... an unfortunate side effect, researchers report: The protein-bound ... melting even when temperatures warm. , The ... the National Academy of Sciences . , "We ... of the evolution of antifreeze proteins in Antarctic ...
(Date:9/22/2014)... of the fires captured in this image burn in Khabarovsk ... Okhotsk. Dozens of red hotspots, accompanied by plumes of smoke ... grey, blows to the east towards the Sea of Okhotsk. ... of this area, swampy forest inhabit the central depression, and ... While large wildfires are common in Russia in the summer, ...
Breaking Biology News(10 mins):Experts provide much-needed policy analysis for clinical integration of next generation sequencing 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 3Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 3
... Bread wheat ( Triticum aestivum ) is one of ... the calories consumed by people. Fully 35% of the world,s ... Now an international team of scientists, including a group from ... analysis of its full genome. The study reveals ...
... pro-iBiosphere aims to prepare (= pro), through ... (= sphere) for intelligent (= i) management of biodiversity ... Open Biodiversity Knowledge Management System will play a major ... It will create an authoritative framework including discovery of ...
... published by the U.S. Department of Agriculture,s (USDA) Economic ... the journal Science examine the relationship between ... and their importance in agricultural input industries. The ... study that provides new details on the rapid growth ...
Cached Biology News:Bread wheat's large and complex genome is revealed 2Bread wheat's large and complex genome is revealed 3Toward an European open biodiversity knowledge management system 2USDA study shows trends in public and private agricultural R&D 2
(Date:9/22/2014)... create a highly sensitive chemical sensor based on the ... electronic properties that the researchers were able to exploit ... times. , The study is available online in advance ... Salehi- Khojin, asst professor of mechanical and industrial engineering ... Bijandra Kumar, post doc where they are doing research ...
(Date:9/22/2014)... , Sept. 22, 2014 US demand ... demand for specialty biocides is forecast to rise 3.9 ... volume terms, demand is projected to increase 1.3 percent ... period. A strong rebound in construction expenditures will support ... and coatings markets, while growth in consumer spending and ...
(Date:9/22/2014)... 2014 Follow us on ... young has groomed and nurtured anti-aging products and ... emphasis on appearance maintenance is benefitting the market ... protein obtained from the bacterium, Clostridium Botulinum, which ... relaxation. With cosmetic indications for botulinum toxin ranging ...
(Date:9/22/2014)... TORONTO , Sept. 22, 2014 ... announced that it has entered into a collaboration ... UHN,s Centre for Molecular Design and Preformulations (CMDP) ... The goal of the project is to increase ... proprietary buccal insulin spray product, thereby reducing the ...
Breaking Biology Technology:Graphene imperfections key to creating hypersensitive 'electronic nose' 2US Biocides Market 2US Biocides Market 3Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 2Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 3Generex Collaborates with University Health Network for Buccal Insulin Project 2Generex Collaborates with University Health Network for Buccal Insulin Project 3Generex Collaborates with University Health Network for Buccal Insulin Project 4
... Massachusetts and LAUSANNE, Switzerland, August 6 /PRNewswire/,-- Curis, ... development company focused on,developing proprietary targeted medicines for ... companies with a focus on the development of,prescription ... that they,have entered into a worldwide, exclusive license ...
... China, Aug. 6 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical,Inc. ... CSKI ), a leading,fully integrated pharmaceutical company producing ... announced the appointment of Mr.,William Wei Lee as an ... effective August 4, 2009. Mr. Jiang Qi-Feng resigned from ...
... 6 Interleukin Genetics, Inc. (NYSE Amex: ... conference call and webcast on Thursday, August 13, 2009, at 4:30 ... financial results. , , To access the live ... replay access of the teleconference will be available on the Investors ...
Cached Biology Technology:Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 2Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 3Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 4Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 5Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 6China Sky One Medical, Inc. Appoints New Independent Director 2China Sky One Medical, Inc. Appoints New Independent Director 3
... is an integrated digital microscope and camera ... equipment setup, optical adjustment or software installation. ... technology, COOLSCOPE combines simplicity and advanced technology ... offers simultaneous viewing of a macro image ...
... DASGIP Overhead Drive for individual and parallel ... flexible agitation of DASGIP vessels, featuring range ... ,Up to 16 overhead drives can ... Cultivation Systems fedbatch-pro® and cellferm-pro® for microbiology ...
This kit is designed to select cells labeled with biotinylated antibodies. Kit includes reagents for labeling 3 x 10 9 cells and EasySep magnet....
Designed for use with the Agencourt CleanSEQ and Agencourt AMPure 384-well SPRI reagent kits. For use with 384-well thermal cycling plates....
Biology Products: