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Antioxidant selenium offers no heart-disease protection

alth habits, education and body mass index also was collected.

Participants provided blood samples at their respective clinics twice a year and reported any new illnesses or medications. Individuals were followed for an average of 7.6 years.

Results showed no association between selenium supplementation on any of the endpoints studied: coronary heart disease, stroke or deaths from cardiovascular disease, Stranges said. There also was no difference in the endpoints based on the level of selenium at baseline. In addition, the lack of significant association with CVD endpoints was confirmed even in the 246 participants who had CVD at baseline. (This data does not appear in the published manuscript.)

"These results must be interpreted cautiously," said Stranges, "because they result from exploratory analyses, although from the largest randomized clinical trial available that has selenium only as the intervention. However, this report adds important information to our knowledge on the role of selenium in cardiovascular-disease prevention, indicating no overall benefit of supplementation by selenium alone in prevention of cardiovascular disease."


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Source:University at Buffalo


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